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Von Willebrand Factor Antibody (VWF/1767), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP24497A30 Shop All R&D Systems Products
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NP24497A30 0.1 mL
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Catalog No. NP24497A30 Supplier Novus Biologicals Supplier No. NBP254497AF350
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Description

Mouse Monoclonal Antibody

Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Von Willebrand Factor
Applications Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone VWF/1767
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Gene Symbols VWF
Host Species Mouse
Immunogen Recombinant fragment (around aa1815-1939) of human Von Willebrand Factor protein (exact sequence is proprietary) (Uniprot: P04275)
Purification Method Protein A or G purified
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 7450.0
Test Specificity von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ
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