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  5. Tocris Bioscience™ VU 0360172 hydrochloride

Tocris Bioscience™ VU 0360172 hydrochloride
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Catalog No. 432310
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Positive allosteric modulator of mGlu5 receptors

Positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM). Selective for mGlu5; displays no significant activity at mGlu1, mGlu2 or mGlu4 receptors. Exhibits antipsychotic-like activity in a rodent model. Also reduces spontaneous spike and wave discharges without affecting motor behaviour in a rat model of absence epilepsy.

Chemical Identifiers

CAS 1309976-62-2
Molecular Formula C18H16ClFN2O

Specifications

Quantity 10 mg
Formula Weight 330.78
Purity >98%
Molecular Weight (g/mol) 330.787
Chemical Name or Material VU 0360172 hydrochloride

Safety and Handling

Recommended Storage Store at +4°C
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