Tocris™ WH-4-023

Potent and selective Lck and Src inhibitor; also inhibits SIK

Manufacturer: Tocris™ 5413/50

 View more versions of this product

Catalog No. 54-135-0

  Check Availability
Add to Cart

Disclaimers:

For Research Use Only


    Specifications

    Product Type WH-4-023
    Inhibitors WH-4-023
    Purity >98
    Molecular Weight 568.67
    Quantity 50mg

    Potent and selective Lck and Src inhibitor (IC50 values are 2 and 6nM respectively). Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases. Supports self-renewal of naive hESCs in combination with PD 0325901, CHIR 99021 and SB 590885.

    • Chemical Name: 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate
    • Formula: C32H36N6O4
    • CAS Number: 837422-57-8
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit