WSB1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-7357	Proteintech Group Inc 116661AP150UL	150 μL

Description

WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.

Specifications

• Antigen: WSB1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q9Y6I7
• Gene ID (Entrez): 26118
• Immunogen: WSB1 Fusion Protein Ag2211
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: WSB1

• Concentration: 0.37 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: SWIP1, WSB 1, WSB1
• Gene Symbols: WSB1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody