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  5. Tocris Bioscience™ WZB 117

Tocris Bioscience™ WZB 117
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Catalog No. 614325
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

GLUT inhibitor

WZB 117 is a GLUT inhibitor (Ki(app) values are 0.2, 10 and 10 μM for GLUT4, GLUT1 and GLUT3, respectively). Competitive inhibitor of net glucose uptake but a noncompetitive inhibitor of sugar efflux from cells. Inhibits passive sugar transport in human erythrocytes and cancer cell lines. Attenuates erythrocyte 3-O-metylglucose (3MG) uptake in vitro (Ki = 6 μM). Suppresses tumor growth in a nude mouse model.

Specifications

Chemical Name or Material 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate)
CAS 1223397-11-2
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C20H13FO6
Formula Weight Observed MW: 368.31
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