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xCT Polyclonal Antibody, Rockland™
SDP

Catalog No. p-7191013
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100 μg
25 μL
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Catalog No. Quantity
50-199-2099 100 μg
50-199-2100 25 μL
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Catalog No. 50-199-2099 Supplier Rockland Immunochemicals Supplier No. 600401GU3
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Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human xCT. Blast analysis of the sequence of the immunogen shows 100% identity with human and orangutan, and 88% identity to mouse.

SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.

Specifications

Antigen xCT
Applications ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene SLC7A11
Gene Accession No. Q9UPY5
Gene Alias 9930009M05Rik; AI451155; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; CCBR1; cysteine/glutamate transporter; Cystine/glutamate transporter; Slc7a11; sodium independent anionic amino acid transport system; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; Solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; sut; xCT
Gene Symbols SLC7A11
Host Species Rabbit
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23657
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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