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Tocris Bioscience™ XMD 8-92
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Quantity:
10 mg
50 mg
Description
ERK5 (BMK1) and BRD4 inhibitor (Kd values are 80 and 190 nM, respectively). Also inhibits DCAMKL2, PLK4 and TNK1 (Kd values are 190, 600 and 890 nM). Blocks growth factor-induced activation of cellular BMK1 and reduces BMK1 activity in in vitro kinase assays. Also reduces BMK1-dependent transactivating activity of MEF2C. Inhibits proliferation in a variety of cancer cell lines; blocks tumor cell proliferation and tumor-associated angiogenesis.
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Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 474.55 |
| Purity | >98% |
| Molecular Weight (g/mol) | 474.565 |
| Chemical Name or Material | XMD 8-92 |
Safety and Handling
| Recommended Storage | Store at Room Temperature |
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