Epredia™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody.

Catalog Number	Mfr. No.	Form	Quantity
MS1393R1	Epredia™ MS1393R1	Ready-to-Use	1 mL

Description

X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.

Host Species: Mouse

Clone: 144

Isotype: IgG2a/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XRCC1 protein

Molecular Weight: 85kDa

Positive Control: Ls174T, or HeLa cells; normal testis

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Clone: 144
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: DNA Repair
• Immunogen: Recombinant human XRCC1 protein
• Primary or Secondary: Primary

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG2a κ