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  8. Y-27632 dihydrochloride, Tocris Bioscience™ 

Y-27632 dihydrochloride, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
1mg
10mg
50mg
This item is not returnable. View return policy
129830-38-2
C14H23Cl2N3O
320.258
IDDDVXIUIXWAGJ-DDSAHXNVSA-N
y-27632 dihydrochloride,y 27632 dihydrochloride,unii-q9828ii7f3,1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexanecarboxamide dihydrochloride,1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride,y 27632 hydrochloride,4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride,1r,4r-4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride,r-+-trans-4-1-aminoethyl-n-4-pyridyl cyclohexanecarboxamide dihydrochloride
9901617
4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
This item is not returnable. View return policy
129830-38-2
C14H23Cl2N3O
320.258
IDDDVXIUIXWAGJ-DDSAHXNVSA-N
y-27632 dihydrochloride,y 27632 dihydrochloride,unii-q9828ii7f3,1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexanecarboxamide dihydrochloride,1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride,y 27632 hydrochloride,4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride,1r,4r-4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride,r-+-trans-4-1-aminoethyl-n-4-pyridyl cyclohexanecarboxamide dihydrochloride
9901617
4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

Description

Selective p160ROCK inhibitor

Selective p160 ROCK inhibitor (Ki values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, PKA and MLCK respectively). Also inhibits PRK2 (IC50 = 600 nM). Smooth muscle relaxant and orally active in vivo. Increases survival rate of human embryonic stem (hES) cells and iPSC-BMECs undergoing cryopreservation. Also optimizes naïve human pluripotent stem cell growth and viability following naïve cell derivation from primed ESCs and iPSCs using naïve human stem cell medium (NHSM).

Y-27632 synthesized to cGMP guidelines also available.

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Quantity 1mg
Formula Weight 320.26
Percent Purity >98%
Chemical Name or Material Y-27632 dihydrochloride

Safety and Handling

Recommended Storage : Desiccate at Room Temperature