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Tocris Bioscience™ ZJ 43
Glutamate carboxypeptidase II and III (NAALADase, NAAG peptidase) inhibitor
Specifications
| CAS | 723331-20-2 |
|---|---|
| Solubility | Soluble to 100mM in DMSO |
| Molecular Formula | C12H20N2O7 |
| Formula Weight | Observed MW: 304.3 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
26-751-R
|
Tocris Bioscience™
2675/1 |
1 mg | Item Discontinued This item has been discontinued by the manufacturer and is no longer available. Please reach out to your sales representative. | N/A | |||||
|
26-751-0
|
Tocris Bioscience™
2675/10 |
10 mg | Item Discontinued This item has been discontinued by the manufacturer and is no longer available. Please reach out to your sales representative. | N/A | |||||
Description
Potent inhibitor of glutamate carboxypeptidase II and III (GCP II and III/NAAG peptidase/NAALADase) (Ki values are 0.8 and 23 nM respectively) that inhibits the hydrolysis of NAAG (IC50 = 2.4 nM) . Does not directly interact with NMDA or metabotropic glutamate receptors. Reduces neuronal degeneration in a rat model of traumatic brain injury (TBI) and reduces locomotor activity in the PCP-model of schizophrenia.Specifications
| 723331-20-2 | |
| Soluble to 100mM in DMSO | |
| C12H20N2O7 | |
| Observed MW: 304.3 |
Safety and Handling
Recommended Storage : Store at -20°C
For Research Use Only
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