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  5. Tocris Bioscience™ ZK 200775

Tocris Bioscience™ ZK 200775
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Catalog No. 234510
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Competitive non-NMDA iGluR antagonist

Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo.

Chemical Identifiers

CAS 161605-73-8
Molecular Formula C14H15F3N3O6P

Specifications

Quantity 10 mg
Formula Weight 409.25
Purity >99%
Molecular Weight (g/mol) 409.258
Chemical Name or Material ZK 200775

Safety and Handling

Recommended Storage Desiccate at +4°C
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