Invitrogen™ ZNF366 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110893

Catalog No. PIPA5110893

Description

Immunogen sequence: DLAVKKTPSF PHCLQPVASR GKAPQRHPFP EALRGPFSQF RYEPPPGDLD GFPGVFEGAG SRKRKSMPTK MPYNH.

Zinc finger protein 366 (ZNF366), also known as Zinc finger estrogen receptor binding domain-containing protein 1, is a gene located on chromosome 5q31.2 that encodes a transcription factor characterized by zinc finger domains. These domains are crucial for DNA binding, allowing ZNF366 to regulate gene expression by interacting with specific DNA sequences. ZNF366 is involved in modulating the activity of various signaling pathways, including those related to hormone receptors, such as the estrogen receptor, impacting cellular processes like development, differentiation, and proliferation. The protein's specific functional roles are still under investigation, but it is thought to contribute to transcriptional regulation and chromatin remodeling. Altered expression or mutations of ZNF366 have been associated with certain cancers, particularly breast cancer, where its regulatory functions may influence tumorigenesis. Research on ZNF366 continues to explore its potential role in disease mechanisms and therapeutic strategies, particularly in oncology and endocrine-related disorders.

Specifications

• Antigen: ZNF366
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Znf366
• Gene Alias: DCSCRIPT; DC-SCRIPT; Dendritic cell-specific transcript protein; Zinc finger protein 366; ZNF366
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 167465
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N895
• Gene Symbols: Znf366
• Immunogen: Recombinant Protein corresonding to Human ZNF366. Recombinant protein control fragment (Product #RP-93623).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov