Invitrogen™ ZNF366 Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5110893	Invitrogen™ PA5110893	100 μL

Description

Immunogen sequence: DLAVKKTPSF PHCLQPVASR GKAPQRHPFP EALRGPFSQF RYEPPPGDLD GFPGVFEGAG SRKRKSMPTK MPYNH.

Zinc finger protein 366 (ZNF366), also known as Zinc finger estrogen receptor binding domain-containing protein 1, is a gene located on chromosome 5q31.2 that encodes a transcription factor characterized by zinc finger domains. These domains are crucial for DNA binding, allowing ZNF366 to regulate gene expression by interacting with specific DNA sequences. ZNF366 is involved in modulating the activity of various signaling pathways, including those related to hormone receptors, such as the estrogen receptor, impacting cellular processes like development, differentiation, and proliferation. The protein's specific functional roles are still under investigation, but it is thought to contribute to transcriptional regulation and chromatin remodeling. Altered expression or mutations of ZNF366 have been associated with certain cancers, particularly breast cancer, where its regulatory functions may influence tumorigenesis. Research on ZNF366 continues to explore its potential role in disease mechanisms and therapeutic strategies, particularly in oncology and endocrine-related disorders.

Specifications

• Antigen: ZNF366
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: Znf366
• Gene Alias: DCSCRIPT; DC-SCRIPT; Dendritic cell-specific transcript protein; Zinc finger protein 366; ZNF366
• Gene Symbols: Znf366
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography

• Concentration: 0.05 mg/mL
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N895
• Gene ID (Entrez): 167465
• Immunogen: Recombinant Protein corresonding to Human ZNF366. Recombinant protein control fragment (Product #RP-93623).
• Product Type: Antibody