Carbohydrates
Medchemexpress LLC Disodium 5'-inosinate | 4691-65-0 | 99.7% | 1 ML
Disodium 5'-inosinate is a nucleotide-based umami agent that binds to umami receptors and stimulates taste nerves, allowing the brain to perceive umami. It can also produce a transient behavioral excitement in mice.
- Binds to umami receptors and stimulates taste nerves.
- Produces transient behavioral excitement in mice.
- Effective in stimulating oral responses in rat solitary-tract nucleus neurons, involved in encoding umami taste.
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC Lecithins, egg | 93685-90-6 | 25 MG
Lecithins, egg are pharmaceutical excipients, also known as pharmaceutical auxiliaries. These are chemical substances, other than active pharmaceutical ingredients, used in the pharmaceutical process. They are generally inactive ingredients in pharmaceutical preparations, improving stability, solubility, and processability. Additionally, they can influence the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
- Purity: 99.0%
- Appearance: Oil
- Color: Light yellow to brown
- Solubility: Soluble in ethanol (≥ 100 mg/mL)
Sigma Aldrich Fine Chemicals Biosciences Sorbitol European Pharmacopoeia (EP) Reference Standard | 50-70-4 | MFCD00004708 |
Sorbitol European Pharmacopoeia (EP) Reference Standard | Mol Wt: 182.17 | 50-70-4 | MFCD00004708 |
Apexbio Technology LLC Cytochalasin D 22144-77-0 1mg
Cytochalasin D is a selective inhibitor of actin polymerization with a reported IC50 value of approximately 25 nM It exerts its biological effect by disrupting the formation and stability of actin filaments thereby influencing cellular processes dependent on cytoskeletal organization Through this mechanistic action Cytochalasin D induces cell cycle arrest at the G1-S transition via activation of p53-related signaling pathways In neuronal studies treatment with Cytochalasin D interferes with filopodial and lamellipodial dynamics by limiting protrusion elongation Additionally in vitro investigations demonstrated its utility in the study of virus-host interactions where blockade of actin polymerization inhibits pathogen entry and replication making Cytochalasin D a relevant reagent in cellular biology and virology research
Sigma Aldrich Fine Chemicals Biosciences Sorbitol | 50-70-4 | MFCD00004708 | 125 mg
Sorbitol | Mol Wt: 182.17 | 50-70-4 | MFCD00004708 | 125 mg
Medchemexpress LLC D-Thyroxine | 51-49-0 | 98.0% | C15H11I4NO4 | 25 MG
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. It can inhibit goiter, promote metamorphosis of tadpoles, and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia. This product is intended for research applications only.
- Orally active thyroid hormone
- Inhibits the secretion of TSH
- Can inhibit goiter
- Promotes metamorphosis of tadpoles
- Influences cholesterol metabolism
- Used for the study of hypercholesterolemia
Medchemexpress LLC D-Glucose | 50-99-7 | MFCD00063684 | 98.0% | 1 G
D-Glucose is the naturally occurring form of glucose and the most abundant monosaccharide. It is a critical component of general metabolism and serving as a significant signaling molecule related to cellular metabolic status and biotic or abiotic stress response. This biologically active stereoisomer of glucose serves as the primary energy source for living organisms.
- Most abundant monosaccharide
- Critical component of general metabolism
- Signaling molecule in cellular metabolic status and stress response
- Primary energy source for living organisms
- Used as a standard for total sugar estimation
- Utilized in preparing liquid media for culturing yeast cells
- Therapeutically used in fluid and nutrient replacement
Medchemexpress LLC HA/hemagglutinin protein, H16N3 | >95.0% | 50 UG
Recombinant hemagglutinin (HA) protein from Influenza A H16N3 (accession AAV91217), expressed in Sf9 insect cells with a C-terminal His tag. Supplied as a 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4; molecular weight ≈58.6 kDa and endotoxin <1 EU/μg. Intended for antibody generation, ELISA, and structural or functional studies. Store at -80 °C; shipped on dry ice.
- Recombinant hemagglutinin from Influenza A H16N3.
- Expressed in Sf9 insect cells to support proper folding.
- C-terminal His tag to facilitate purification and detection.
- Supplied as a 0.22 μm filtered formulation for stability.
- Formulation: 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4.
- Endotoxin level below 1 EU per microgram.
- Suitable for immunization, ELISA, and biophysical characterization.
Medchemexpress LLC K-Ras ligand-Linker Conjugate 6 formate | 98.9% | 25 MG
K-Ras ligand-Linker Conjugate 6 formate is a chemical compound with the molecular formula C43H62N8O9 and a molecular weight of 835.00. This compound is provided in an off-white to light yellow solid form and is suitable for various laboratory applications requiring high purity chemical reagents.
- High purity of 98.93% verified by HPLC
- Appears as an off-white to light yellow solid
- Store at -20°C in sealed conditions, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month in sealed conditions
- Analytical data (1H NMR spectrum, MS) are consistent with its structure
Medchemexpress LLC Methyl α-D-galactopyranoside | 3396-99-4 | 99.6% | 194.18 | C7H14O6 | 10 G
Methyl α-D-galactopyranoside is a methyl glycoside of D-galactose used as a biochemical reagent in glycobiology research and assays. It is typically supplied as a solid suitable for laboratory use.
- Purity 99.58%.
- Molecular weight 194.18 g/mol.
- Chemical formula C7H14O6.
- CAS number 3396-99-4.
- Solid appearance, suitable for biochemical assays and glycobiology applications.
Apexbio Technology LLC 5-Azacytidine 320-67-2 10mM (in 1mL DMSO)
5-Azacytidine is a cytidine analog compound that functions as an inhibitor of DNA methyltransferase (DNMT) Its mechanism involves incorporation into cellular DNA/RNA followed by covalent binding to DNMT through the formation of a bond between the C6 position of 5-Azacytidine and the thiol group of cysteine residues in DNMT enzymes leading to reduced DNMT activity and subsequent DNA demethylation In cellular studies involving multiple myeloma (MM) 5-Azacytidine exhibits cytotoxicity against MM-derived cell lines (MM 1S MM 1R RPMI-8266 RPMI-LR5 RPMI-Dox40) with reported IC50 values of approximately 1 5 mol/L 0 7 mol/L 1 1 mol/L 2 5 mol/L and 3 2 mol/L respectively as well as patient-derived MM cells (IC50 1 5 mol/L) This compound is widely used in cancer research to investigate epigenetic regulation mechanisms and DNA methylation pathways
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Medchemexpress LLC Beta-D-Glucopyranosyl nitromethane | 81846-60-8 | 99.94% | C7H13NO7 | 50 MG
Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane, utilized as a salt of a strongly basic anion exchanger in the OH cycle. This product is designed exclusively for research purposes.
- Functions as a salt of a strongly basic anion exchanger.
- Intended for research use only.