Carbohydrates
Medchemexpress LLC 4-Methylumbelliferyl | 124223-99-0 | MFCD00270047 | 99.0% | 379.36 g/mol | C18H21NO8 | 1MG
4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is a fluorogenic glycoside substrate that liberates 4-methylumbelliferone upon enzymatic hydrolysis, enabling sensitive fluorescence-based detection of glycosidase activity in biochemical assays.
- Releases a fluorescent reporter for sensitive enzyme assays
- High purity (99.0%) for consistent assay performance
- White to off-white solid, easy to handle and dissolve
- Suitable for measuring glycosidase activity in biochemical assays
- Stable under recommended storage for long-term use
Alkali Scientific 4 Methylumbelliferyl β D cellobiopyranoside, 100 Mg
Methylumbelliferyl Cellobiopyranoside is a high-purity reagent used in biochemical analysis to assess the activity of cellulase enzymes, particularly those involved in the breakdown of cellulose and related polysaccharides. This 100mg reagent is essential for enzyme assays designed to measure the hydrolysis of cellobiose or other cellulose derivatives. It is widely utilized in studies of plant biomass degradation, biofuel production, and the enzymatic processing of agricultural and industrial waste. The high purity of this reagent ensures consistent and reliable results in laboratory experiments focusing on cellulase activity and cellulolytic enzymes.
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC SN-38 glucuronide | 121080-63-5 | 99.5% | 568.53 | 1 MG
SN-38 glucuronide, also known as SN-38G, is an inactive metabolite of the anticancer molecule Irinotecan. It has known toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor used in research for colon and rectal cancer. SN-38 glucuronide can be reactivated by gut microbial β-glucuronidase enzymes, which remove the glucuronic acid moiety, thus increasing its toxic effects on the intestine.
- Inactive metabolite of Irinotecan.
- Has toxic effects on the gastrointestinal tract.
- Can be reactivated by gut microbial β-glucuronidase enzymes.
- Relevant in the study of colon and rectal cancer.
- Cells metabolizing SN38 to SN38-G show increased resistance to extracellular SN38.
AdipoGen 3OH-C10-L-HSL
Chemical. CAS 192883-12-8. Formula C14H25NO4. MW 271.35. Synthetic. N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.