Carbohydrates
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 5 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, it modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin
- Modulates gut microbiota by increasing beneficial bacterial populations
- Suppresses harmful bacterial populations
- For research use only
- Purity of 98.0%
Medchemexpress LLC D-Arabinopyranose | 28697-53-2 | 25 MG
D-Arabinopyranose is a monosaccharide and an analytical standard intended for research and analytical applications. It has been shown to exhibit strong growth inhibition against Caenorhabditis elegans with an IC50 of 7.5 mM.
- Analytical standard for research and analytical applications
- Exhibits strong growth inhibition against Caenorhabditis elegans
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
- Reference standard supplied for assay
Medchemexpress LLC Cytochalasin D | 22144-77-0 | 25 MG
Cytochalasin D (Zygosporin A) is a potent, cell-permeable inhibitor of actin polymerization, derived from fungus. It works by binding to G-actin, thereby inhibiting the interaction between G-actin and cofilin. This action also reduces the binding of cofilin to F-actin, consequently decreasing the rate of both actin polymerization and depolymerization in living cells.
- Effectively disrupts the dynamics of actin filaments.
- Can easily enter cells to exert its effects.
- Prevents cofilin from interacting with G-actin.
- Modulates actin dynamics within cells.
- Can lower the amount of survivin in the tumor environment by reducing exosome release.
- Affects the localization and activity of the Yap protein.
Medchemexpress LLC β-D-glucopyranosiduronic acid derivative (p-nitrophenyl carbonate methyl ester) | 894095-98-8 | MFCD31715405 | 99.2% | 913.83 | C45H43N3O18 | 100 MG
β-D-glucuronide-pNP-carbonate is a cleavable antibody-drug conjugate (ADC) linker used as a building block in the synthesis of ADCs. It features a p-nitrophenyl (pNP) carbonate leaving group attached to a β-D-glucuronide moiety, enabling enzymatic or chemical cleavage to release payloads for targeted delivery. Intended for research use only.
- Cleavable glycosidase-sensitive linker for controlled payload release.
- p-Nitrophenyl carbonate activation enables facile coupling to amines.
- High purity suitable for synthetic and medicinal chemistry workflows.
- Available as a solid reagent in small research quantities for laboratory use.
Medchemexpress LLC Naproxen glucuronide 1mg
Naproxen glucuronide ((S)-Naproxen- -D-glucuronide) is a non-selective COX inhibitor Naproxen glucuronide a metabolite of naproxen is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain fever swelling and stiffness[1]
Medchemexpress LLC PROTAC BET degrader- 1mg | 3031993-61-7 | 1 MG
PROTAC BET degrader-3 is a proteolysis-targeting chimera that links a von Hippel-Lindau (VHL) ligand to a BET ligand to induce targeted proteasomal degradation of BET proteins. It is supplied as a light-yellow solid for research use.
- Induces VHL-mediated degradation of BET proteins.
- Molecular formula C53H64N12O9S; molecular weight 1045.22 g·mol⁻¹.
- Reported purity 99.11%.
- Available in small milligram quantities for screening and cell-based studies.
- Store powder at -20°C; in solution store at -80°C for long term.
Medchemexpress LLC Fenclofenac 50mg | 34645-84-6 | 297.13 | 50 MG
Fenclofenac (CAS 34645-84-6) is a nonsteroidal anti-inflammatory research compound provided as a high-purity reference standard for biochemical and pharmacological studies. It is supplied in small pack sizes and includes supporting documentation such as a certificate of analysis and a safety data sheet.
- High purity 99.09%.
- Available in small pack sizes including 50 mg.
- Molecular formula C14H10Cl2O3; molecular weight 297.13.
- Provided with datasheet, COA, and SDS for research use.
- Suitable as a reference standard for pharmacology and analytical studies.
Medchemexpress LLC PROTAC BET degrader-1 | 2093386-22-0 | 99.4% | 871.9 g/mol | C44H45N11O9 | 100 MG
PROTAC BET Degrader-1 is a proteolysis-targeting chimera (PROTAC) that links Cereblon and BET ligands to promote ubiquitin-mediated degradation of BET family proteins BRD2, BRD3, and BRD4 at low concentrations. It is supplied for research use in studies of BET protein biology and targeted protein degradation.
- Induces degradation of BRD2, BRD3, and BRD4 at low nanomolar concentrations.
- High purity (99.4%) suitable for biochemical and cell-based assays.
- Available as solid or as DMSO solution for experimental flexibility.
- High solubility in DMSO (≥ 50 mg/mL) for convenient dosing.
- Stable when stored per manufacturer recommendations for long-term experiments.
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Medchemexpress LLC Cimiracemoside D | 290821-39-5 | MFCD28411517 | 99.9% | 678.85 | C37H58O11 | 10 MG
Cimiracemoside D is a natural glycoside isolated from the plant Actaea racemosa and supplied as a high-purity research reagent. It is characterized by molecular formula C37H58O11, molecular weight 678.85, and CAS number 290821-39-5. The compound is offered as a solid and in DMSO solution formats for laboratory use.
- High purity (99.9%).
- Natural source: Actaea racemosa.
- Molecular formula C37H58O11, molecular weight 678.85.
- Available in solid form and as 10 mM DMSO solutions.
- Intended for research use only.
Medchemexpress LLC IL-18RAP Rhesus Mac 5ug | 5ug
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells
Apexbio Technology LLC HyperTrap Heparin HP Column(Synonyms: Heparin Affinity Column, Heparin HP Column, HyperTrap Heparin Affinity Chromatography Column), 5ml.
HyperTrap Heparin HP Column features the HyperChrom Heparin HP Agarose affinity chromatography resin which consists of heparin covalently immobilized on an agarose matrix Heparin is a naturally occurring glycosaminoglycan known for specific affinity interactions with various biomolecules including coagulation factors growth factors interferons lipoprotein lipase nucleic acid-binding proteins steroid receptors and antithrombin III This column enables efficient separation and purification of these proteins making it suitable for biochemical research proteomics analyses and protein characterization studies
Medchemexpress LLC 1-Propanone, 3-(2,4-dihydroxy-6-methoxyphenyl)-1-(4-hydroxyphenyl)- | 119425-91-1 | 10 MG
Loureirin D is a dihydrochalcone found in dragon's blood. This product is for research use only and has not been fully validated for medical applications.
- Dihydrochalcone found in dragon's blood
- Purity of 99.30%
- Molecular formula: C16H16O5
- Molecular weight: 288.30
- Appears as a white to pink solid
- Store at 4°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
- Soluble in DMSO (≥ 50 mg/mL)
- Structure consistent with 1H NMR and LCMS
Medchemexpress LLC D-Glucuronic acid | 6556-12-3 | 1 G
D-Glucuronic acid is a key component of anti-inflammatory proteoglycans, promoting embryonic development and inhibiting cell aggregation. When metabolized into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), contributing to pain. This acid and its derivative, glucurono-lactone, act as liver detoxifiers for human health and show anti-tumor activity.
- Key component of anti-inflammatory proteoglycans.
- Promotes embryonic development.
- Inhibits cell aggregation.
- Acts as a liver detoxifier.
- Derivatives exhibit anti-tumor activity.
- Activates Toll-like receptor 4 (TLR4) when metabolized.