Carbohydrates
Medchemexpress LLC Fulvestrant 3-β-D-Glucuronide | 261506-27-8 | 94.79% | 782.89 | 1 MG
Fulvestrant 3-β-D-Glucuronide is a metabolite derived from Fulvestrant, a pure anti-estrogenic steroid. It is characterized as a glucuronide and sulfate conjugate. This compound is primarily intended for breast cancer research.
- Derived from an anti-estrogenic steroid.
- Exists as glucuronide and sulfate conjugates.
- Applicable in breast cancer research.
- Solid appearance, white to off-white in color.
- High purity of 94.79%.
Medchemexpress LLC (S)-Ibuprofen acyl-β-D-glucuronide | 98649-76-4 | 98.5% | 382.40 | 1 MG
(S)-Ibuprofen acyl-β-D-glucuronide is a compound used to study the metabolism and pharmacokinetics of S-ibuprofen, which is a non-steroidal anti-inflammatory drug. It is an acylglucuronic acid metabolite produced from S-ibuprofen in the liver. This product is intended for research use only.
- Used for studying metabolism.
- Used for pharmacokinetic research.
- Derived from a common anti-inflammatory drug.
- Metabolite produced in the liver.
Apexbio Technology LLC HyperTrap Heparin HP Column(Synonyms: Heparin Affinity Column, Heparin HP Column, HyperTrap Heparin Affinity Chromatography Column), 5x1ml.
HyperTrap Heparin HP Column features the HyperChrom Heparin HP Agarose affinity chromatography resin which consists of heparin covalently immobilized on an agarose matrix Heparin is a naturally occurring glycosaminoglycan known for specific affinity interactions with various biomolecules including coagulation factors growth factors interferons lipoprotein lipase nucleic acid-binding proteins steroid receptors and antithrombin III This column enables efficient separation and purification of these proteins making it suitable for biochemical research proteomics analyses and protein characterization studies
Apexbio Technology LLC HyperTrap Heparin HP Column(Synonyms: Heparin Affinity Column, Heparin HP Column, HyperTrap Heparin Affinity Chromatography Column), 5ml.
HyperTrap Heparin HP Column features the HyperChrom Heparin HP Agarose affinity chromatography resin which consists of heparin covalently immobilized on an agarose matrix Heparin is a naturally occurring glycosaminoglycan known for specific affinity interactions with various biomolecules including coagulation factors growth factors interferons lipoprotein lipase nucleic acid-binding proteins steroid receptors and antithrombin III This column enables efficient separation and purification of these proteins making it suitable for biochemical research proteomics analyses and protein characterization studies
Apexbio Technology LLC HyperTrap Heparin HP Column(Synonyms: Heparin Affinity Column, Heparin HP Column, HyperTrap Heparin Affinity Chromatography Column), 1ml.
HyperTrap Heparin HP Column features the HyperChrom Heparin HP Agarose affinity chromatography resin which consists of heparin covalently immobilized on an agarose matrix Heparin is a naturally occurring glycosaminoglycan known for specific affinity interactions with various biomolecules including coagulation factors growth factors interferons lipoprotein lipase nucleic acid-binding proteins steroid receptors and antithrombin III This column enables efficient separation and purification of these proteins making it suitable for biochemical research proteomics analyses and protein characterization studies
Apexbio Technology LLC Polyphyllin D(Synonyms: Paris saponin VII, Polyphyllin VI, Diosgenyl alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside), 20mg, CAS: 55916-51-3.
Polyphyllin D (CAS 55916-51-3) is a bioactive steroidal saponin isolated from the plant Paris yunnanensis Franch It exhibits significant anticancer activity primarily through induction of apoptosis cell-cycle arrest and inhibition of cell migration and invasion Studies suggest Polyphyllin D mediates its effects via modulation of signaling pathways including PI3K/Akt NF- B and MAPK cascades Due to these mechanistic insights Polyphyllin D serves as a valuable research tool for investigating molecular pathways associated with tumorigenesis and metastatic progression
Apexbio Technology LLC Carbenoxolone disodium 7421-40-1 10mM (in 1mL DMSO)
Carbenoxolone disodium (CAS 7421-40-1) is a small-molecule inhibitor targeting 11 -hydroxysteroid dehydrogenase (11 -HSD) It is designed to modulate glucocorticoid metabolism by suppressing the interconversion of corticosteroid hormones thereby regulating glucocorticoid access to steroid receptors Carbenoxolone disodium exerts its biological activity through inhibition of 11 -HSD enzymatic function In vitro studies demonstrate inhibitory activity with reported IC50 values ranging from 10 30 M depending on experimental conditions and target tissue Based on these pharmacological properties Carbenoxolone disodium holds research potential in neuroendocrine and cardiovascular studies exploring glucocorticoid-mediated signaling pathways
Apexbio Technology LLC Carbenoxolone disodium 7421-40-1 50mg
Carbenoxolone disodium (CAS 7421-40-1) is a small-molecule inhibitor targeting 11 -hydroxysteroid dehydrogenase (11 -HSD) It is designed to modulate glucocorticoid metabolism by suppressing the interconversion of corticosteroid hormones thereby regulating glucocorticoid access to steroid receptors Carbenoxolone disodium exerts its biological activity through inhibition of 11 -HSD enzymatic function In vitro studies demonstrate inhibitory activity with reported IC50 values ranging from 10 30 M depending on experimental conditions and target tissue Based on these pharmacological properties Carbenoxolone disodium holds research potential in neuroendocrine and cardiovascular studies exploring glucocorticoid-mediated signaling pathways
Medchemexpress LLC Ophiopogonin D | 945619-74-9 | 855.02 | 10 MM * 1 ML
Ophiopogonin D is a naturally occurring C29 steroidal glycoside isolated from *Ophiopogon japonicus*. It acts as a CYP2J3 inducer and shows protective effects against inflammatory, metabolic, and cardiovascular diseases.
- Inhibits Ang II induced NF-κB nuclear translocation.
- Increases expression of CYP2J2/EETs and PPARα in HUVECs.
- Inhibits osteoclastic differentiation in RAW264.7 cells.
- Protects against H2O2-induced endothelial injury as an antioxidant.
- Blocks ERK signaling cascades.
- Alleviates high-fat diet-induced metabolic syndrome.
Medchemexpress LLC Pregnanediol 3-glucuronide | 1852-49-9 | 98.0% | 496.63 g·mol⁻¹ | C27H44O8 | 5 MG
Pregnanediol 3-glucuronide is the primary urinary metabolite of the steroid hormone progesterone, formed by hepatic hydroxylation and glucuronidation. It is highly hydrophilic and readily excreted in urine, and is used in research and clinical assays as a biochemical marker to monitor ovulation, evaluate luteal function, and study reproductive endocrinology.
- Primary urinary metabolite of progesterone.
- Highly hydrophilic and readily excreted in urine.
- Serves as a biochemical marker to monitor ovulation and luteal function.
- Suitable for use in analytical and clinical assays.
- Available in small, research-grade quantities for reference standards.
Medchemexpress LLC Ophiopogonin D' | 65604-80-0 | 1 MG
Ophiopogonin D' is a steroidal saponin and a SIRT1 activator. It regulates the activities of transporters OATP1B1 and OATP1B3 and exhibits certain toxicity to tumor cells, making it suitable for tumor research.
- SIRT1 activator
- Regulates OATP1B1 and OATP1B3 transporter activities
- Exhibits toxicity to tumor cells
- Suitable for tumor research
- Has IC50 values of 3.09 μM for MG-63 cells and 3.63 μM for SNU387 cells
- Promotes uptake of Rosuvastatin and Atorvastatin in OATP1B1-HEK293T cells
- Increases Rosuvastatin uptake and reduces Telmisartan uptake in OATP1B3-HEK293T cells
Medchemexpress LLC Cholesterol β-D-glucoside | 7073-61-2 | MFCD00056433 | 99.4% | C33H56O6 | 10MG
Cholesterol β-D-glucoside is a steroid glycoside used as a research reagent to activate heat shock transcription factor 1 (HSF1) and induce HSP70 expression in fibroblast cells. It is provided as a high-purity solid for cell biology and biochemical studies of heat-shock response pathways.
- Activates heat shock transcription factor 1 (HSF1) and induces HSP70.
- High purity (~99.4%) for reliable experimental results.
- Molecular formula C33H56O6; molecular weight 548.79.
- Solid, white to off-white appearance suitable for powder storage.
- Stable when stored at -20°C as powder (3 years) and in solvent at -80°C (6 months).
- Certificate of analysis and safety data sheet are available.
Sigma Aldrich Fine Chemicals Biosciences HiTrapR Heparin High Perfo
HiTrap(R) Heparin HP columns are prepacked with Heparin Sepharose(R) High Performance for high-reSOLUTIONon purification of proteins with affnity for heparin such as DNA-binding proteins coagulation factors lipoproteins and protein synthesis factors.Immobilized heparin has two main modes of interaction with proteins. It can operate as an affinity ligand with affinity for a wide range of biomolecules including coagulation factors and other plasma proteins lipoproteins protein synthesis factors enzymes that act on nucleic acids and steroid receptors. Heparin also functions as a high capacity cation exchanger due to its anionic sulfate groups. Gradient elution with salt is most commonly used in both cases.Heparin is coupled to the Sepharose(R) High Performance base matrix via the N-hydroxysuccinamide coupling method to give high capacity performance and low leakage levels.
Sigma Aldrich Fine Chemicals Biosciences Heparin SepharoseR 6 Fast
Heparin Sepharose(R) 6 Fast Flow is a well established BioProcess affinity medium designed for capture or intermediate purification steps. This medium is extensively used for industrial purification of several marketed plasma proteins.Heparin Sepharose(R) 6 Fast Flow is a member of the Cytiva range of affinity chromatography media for capture and intermediate purification.Heparin Sepharose(R) 6 Fast Flow is composed of cross-linked 6% agarose beads modified sodium heparin. Immobilization is performed using chemically stable and oriented coupling giving high binding capacity. The chemical stability of the media is solely dictated by the heparin ligand.This medium allows for fast and reliable separations of biomolecules with an affinity for heparin including antithrombin III coagulation factors and other plasma proteins. Additional applications include DNA binding proteins lipoproteins protein synthesis factors enzymes that act on nucleic acids and steroid receptors.Heparin Sepharo