Lipids and Lipid Derivatives
Medchemexpress LLC Tributyrin (glyceryl tributyrate) | 60-01-5 | 98.9% | 302.36 | 1 ML
Tributyrin (Glyceryl tributyrate) is a neutral short-chain fatty acid triglyceride that acts as a stable and rapidly absorbed proagent of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. It has potent antiproliferative, proapoptotic, and differentiation-inducing effects.
- Induces significant growth inhibition in PC-3 cells
- Causes G1 cell cycle arrest in LNCaP cells
- Induces higher apoptosis rates in PC-3 and TSU-PR1 cells
- Induces prostate-specific antigen expression in LNCaP cells
- Directly inhibits the production of TNF-α and IL-1β in RAW 264.7 cells under LPS stimulation
- Improves metabolic and inflammatory states in high-fat diet-induced obese mice
- Significantly improves gut microbiota dysbiosis and intestinal injury in a gut dysfunction mouse model
Medchemexpress LLC Glyceryl 1-monooctanoate | 502-54-5 | 99.0% | 218.29 | 5 MG
Glyceryl 1-monooctanoate is a glycerol monolaurate derivative and a broad-spectrum antimicrobial. It suppresses the growth of pathogenic yeast and both Gram-positive and Gram-negative bacteria. This makes it suitable for various laboratory applications.
- Broad-spectrum antimicrobial activity.
- Suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis).
- Suppresses the growth of Gram-positive bacteria (Staphylococcus aureus).
- Suppresses the growth of Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae).
- Antifungal activity against saprophytic fungi (Aspergillus niger, Penicillium roqueforti, Penicillium jensenii, Alternaria sp., Phoma sp.).
- Antifungal activity against pathogenic fungi (Trichophyton mentagrophytes and Trichophyton rubrum).
Medchemexpress LLC Triacetin | 102-76-1 | 99.6% | 1 ML
Triacetin (Glyceryl triacetate) is a synthetic, orally active compound that increases acetate bioavailability in glioma cells. It induces glioma cell growth arrest and apoptosis, freely crossing the blood brain barrier/plasma membrane. This compound also increases histone acetylation and enhances the chemotherapeutic efficacy of Temozolomide. It is intended for research use only.
- Induces growth arrest in various glioma cells
- Inhibits U87MG cell viability
- Induces apoptosis in GBM cancer cells
- Decreases class I and II HDAC mRNA expression
- Inhibits HDAC-8 activity
- Activates mTOR complexes downstream genes
- Increases tumor suppressor miRs
- Enhances chemotherapeutic efficacy with Temozolomide
- Increases survival in animal models with GBM-derived GSCs
Medchemexpress LLC 1,3-glyceryl dilinoleate | 15818-46-9 | MFCD00056310 | ≥95.0% | 616.95 g/mol | C39H68O5 | 100 MG
1,3-Glyceryl dilinoleate is an unsaturated diacylglycerol used as a laboratory research reagent for studies of lipids, lipid signaling, and metabolism. It is an oil composed of glycerol esterified with two linoleic acid chains and is supplied with analytical-grade purity.
- Contains two linoleic acid (18:2) chains esterified to glycerol.
- Suitable for lipid metabolism and signaling studies.
- Provided as a neat oil for analytical and biochemical applications.
- Typical purity ≥95.0%.
- Molecular weight 616.95 g/mol; formula C39H68O5.
Medchemexpress LLC Trilaurin | 538-24-9 | 99.8% | 1 G
Trilaurin is an anticancer agent capable of inhibiting neoplasms initiated by dimethylbenzanthracene (DMBA) and promoted by croton oil. It functions as an endogenous metabolite.
- Inhibits neoplasm formation
- Functions as an endogenous metabolite
- Molecular weight: 639.00
- Chemical formula: C39H74O6
- Appears as a solid
- Color: White to off-white
- Purity: 99.78%
- Soluble in DMSO and DMF
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Tributyrin (glyceryl tributyrate) | 60-01-5 | 98.91% | 302.36 | 5 ML
Tributyrin (Glyceryl tributyrate) is a neutral short-chain fatty acid triglyceride that serves as a stable and rapidly absorbed proagent of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, which releases effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic, and differentiation-inducing effects.
- Enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells.
- Induces differentiation, growth arrest, and apoptosis in androgen-sensitive and androgen-resistant human prostate cancer cell lines.
- Attenuates metabolic and inflammatory changes associated with obesity through a GPR109A-dependent mechanism.
- Alleviates gut microbiota dysbiosis to repair intestinal damage in antibiotic-treated mice.
Electron Microscopy Sciences Triacetin Reagent 0.5 OZ
For your convenience Triacetin Reagent is avaialbe for use with the our Acetone Vaporizer Kit.
Sigma Aldrich Fine Chemicals Biosciences Escin | Purity: 98% | Mol Wt: 1131.19 | CAS No: 6805-41-0 | MDL No: MFCD00130460 | 500mg
Escin | Purity: 98% | Mol Wt: 1131.19 | CAS No: 6805-41-0 | MDL No: MFCD00130460 | 500mg
Medchemexpress LLC HY-135297 100mg Medchemexpress, Mono-and diglycerides CAS: Purity:>98%
Medchemexpress, HY-135297 100mg Mono-and diglycerides CAS: Mono-and diglycerides is formed by triglycerides being broken down by pancreatic lipase in the gastrointestinal lumen. Mono-and diglycerides is a food additive used as a nonionic emulsifier and mainly present in food fats. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Aobchem 1-(Allyloxy)-2-bromo-4-chlorobenzene | ≥95% | CAS 68223-98-3 | C9H8BrClO | 250mg
1-(Allyloxy)-2-bromo-4-chlorobenzene | ≥95% | CAS 68223-98-3 | C9H8BrClO | 250mg
Aobchem 1-(Allyloxy)-2-bromo-4-chlorobenzene | ≥95% | CAS 68223-98-3 | C9H8BrClO | 10g
1-(Allyloxy)-2-bromo-4-chlorobenzene | ≥95% | CAS 68223-98-3 | C9H8BrClO | 10g
Medchemexpress LLC 1 2-Distearoyl-sn-gl 100mg | 108321-18-2 | 100 MG
1,2-Distearoyl-sn-glycero-3-phosphate sodium is a phospholipid (sodium salt) used in research for liposome formulation and drug delivery studies. It acts as a stabilizer and emulsifier to aid in drug encapsulation and improve solubility and bioavailability. Store sealed and protected from moisture for best stability.
- phospholipid useful for liposome formulations
- functions as a stabilizer and emulsifier
- solid, white to off-white appearance
- available in small laboratory pack sizes for research use
- recommended sealed storage to minimize moisture exposure