Nucleosides and Analogues
Apexbio Technology LLC Adenosine 5-triphosphate 34369-07-8 100mg
Adenosine 5-triphosphate (ATP CAS 34369-07-8) also known as ATP disodium salt hydrate is a nucleotide central to cellular energy transfer It functions as the primary intracellular energy carrier undergoing hydrolysis to release energy required for numerous biochemical processes including muscle contraction signal transduction and biosynthetic reactions ATP also serves as a substrate for kinases in phosphorylation events and plays a regulatory role in purinergic signaling pathways In biomedical research ATP is widely used to study cellular metabolism enzyme activities and receptor-mediated responses
Apexbio Technology LLC 2'-Deoxyguanosine 961-07-9 5g
2 -Deoxyguanosine (CAS 961-07-9) is a purine deoxyribonucleoside comprising guanine coupled to a deoxyribose moiety As an essential constituent of DNA it serves as a substrate in multiple nucleotide metabolism pathways Its interconversion with 2 -deoxyguanosine 5 -monophosphate is mediated by purine 5 -nucleotidase and deoxyguanosine kinase reflecting its role in nucleic acid turnover In biomedical research 2 -deoxyguanosine is utilized to study DNA synthesis repair mechanisms and enzymatic processes involving nucleoside metabolism Altered deoxyguanosine homeostasis has been implicated in purine nucleoside phosphorylase deficiency underscoring its significance in inherited metabolic disorders
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 10mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Apexbio Technology LLC Adenosine Kinase Inhibitor (hydrate) 1mg
Adenosine Kinase Inhibitor (hydrate) is a small-molecule inhibitor targeting adenosine kinase It is designed to inhibit adenosine kinase thereby regulating intracellular adenosine metabolism Adenosine Kinase Inhibitor (hydrate) exerts its biological activity primarily through selective enzyme inhibition In cell-free conditions Adenosine Kinase Inhibitor (hydrate) demonstrates potent inhibitory activity with an IC50 value of approximately 1 7 nM Based on these pharmacological properties Adenosine Kinase Inhibitor (hydrate) holds research potential in investigating pain perception mechanisms and inflammation modulation through adenosine signaling pathways
![eMolecules 951-78-0 | 2'-Deoxyuridine | ChemScene | MFCD00006527 | 228.204 | C9H12N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 572244290](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502484797.JPG-250.jpg)
eMolecules 951-78-0 | 2'-Deoxyuridine | ChemScene | MFCD00006527 | 228.204 | C9H12N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 572244290
2'-Deoxyuridine | ChemScene | 951-78-0 | MFCD00006527 | 228.204 | C9H12N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 572244290
Cayman Chemical Adenosine 5'-diphosphate (potassium salt hydrate), Purity: ≥95%, 10 g
An adenine nucleotide containing two phosphate groups
Selleck Chemical LLC 5-Methyl-2 -deoxycytidine
5-Methyl-2 -deoxycytidine (5-Me-dC 5-Methyldeoxycytidine 5MedCyd) is a minor component found in most eukaryotic DNA
Cayman Chemical 5-Formyl-2'-deoxyuridine, Purity: ≥95%, CAS: 4494-26-2, 50 mg
A nucleoside derivative; inhibits the proliferation of BHK-21 cells and Ehrlich ascites tumor cells (IC50s = 4 and 6 µM, respectively); reduces virus yield in psuedorabies-infected BHK-21 cells at 1 mM; a product of oxidative DNA damage in vitro
Cayman Chemical N6-benzoyl-2'-Deoxyadenosine, Purity: ≥95%, CAS: 4546-72-9, 25 g
A nucleoside building block; has been used in the synthesis of various oligonucleotides
TARGETMOL CHEMICALS INC ADENOSINE DIALDEHYDE ADO 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Adenosine Dialdehyde (Periodate-oxidized adenosine) is a purine nucleoside analogue. Adenosine Dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo. purity: 95%
Apexbio Technology LLC NAD+ 53-84-9 10mM (in 1mL H2O)
Nicotinamide adenine dinucleotide (NAD CAS number 53-84-9) is a coenzyme involved in oxidation-reduction reactions accepting electrons to form NADH Additionally NAD functions as a substrate in enzymatic processes mediated by poly(ADP-ribose) polymerases sirtuins and cyclic ADP-ribose synthases NAD analogs demonstrate inhibitory activity against CD38-associated NAD glycohydrolase (NADase) with reported IC50 values ranging from 2 mM to 10 mM In biomedical research NAD supplementation is investigated for addressing fatigue and fatigue-associated disorders
Apexbio Technology LLC UDP disodium salt(Synonyms: Uridine 5'-diphosphate disodium salt, Uridine diphosphate disodium salt, UDP-Na2), 50mg, CAS: 27821-45-0.
UDP disodium salt (CAS 27821-45-0) is a selective agonist targeting the P2Y6 receptor exhibiting potent stimulatory activity with an EC50 value of approximately 300 nM and a reported pEC50 of 6 52 for the human P2Y6 receptor Endogenously UDP serves as a metabolite involved in catalyzing glucuronidation reactions facilitating the conjugation of glucuronic acid to diverse substrates Due to these biological properties UDP disodium salt finds utility in researching disease-related mechanisms and RNA biosynthesis pathways
Apexbio Technology LLC Lamivudine 134678-17-4 50mg
Lamivudine is a nucleoside analog that acts primarily as a reverse transcriptase inhibitor disrupting viral replication by interfering with RNA-dependent DNA polymerase activity It inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with an IC50 value of approximately 0 316 M Lamivudine also suppresses replication of simian retrovirus (SRV-1 and SRV-2) while exhibiting negligible activity on foamy viruses and amphotropic murine leukemia virus (MLV-A) Due to its antiviral mechanism and dual inhibitory effect against both HIV-1 and hepatitis B virus (HBV) lamivudine is frequently utilized in research involving retroviral infection models particularly HIV-1 and HBV coinfection studies to evaluate viral dynamics antiviral efficacy and biochemical responses
Apexbio Technology LLC UDP disodium salt(Synonyms: Uridine 5'-diphosphate disodium salt, Uridine diphosphate disodium salt, UDP-Na2), 10mM (in 1mL H2O), CAS: 27821-45-0.
UDP disodium salt (CAS 27821-45-0) is a selective agonist targeting the P2Y6 receptor exhibiting potent stimulatory activity with an EC50 value of approximately 300 nM and a reported pEC50 of 6 52 for the human P2Y6 receptor Endogenously UDP serves as a metabolite involved in catalyzing glucuronidation reactions facilitating the conjugation of glucuronic acid to diverse substrates Due to these biological properties UDP disodium salt finds utility in researching disease-related mechanisms and RNA biosynthesis pathways
Advanced Chemblocks Inc PSI6206; 5G; 98%
Chemical Name: PSI6206 CAS: 863329-66-2 #N/A MDL Number: MFCD19982668 Category: Reference Compound Synonym: PSI6206
