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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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Synthetic nucleoside analogue structurally related to guanine. Inhibits the replication of a wide range of DNA and RNA viruses.
WARNING! This product can expose you to Ribavirin, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
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2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis.
Used as an analytical standard.
Supports DNA biosynthesis.
Suitable for qualitative research experiments.
Suitable for quantitative research experiments.
Suitable for methodological research experiments in HPLC, GC, and MS.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It can serve as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
Endogenous metabolite
Deoxynucleotide building block of DNA
Substrate for UMP/CMP kinase
Supports DNA biosynthesis
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Deoxycytidine triphosphate-d14 dilithium is a deuterium-labeled nucleoside triphosphate provided as the dilithium salt for use as an isotopic standard or tracer in DNA synthesis workflows, including PCR, sequencing, and analytical method development.
Deuterium-labeled for isotopic tracing and mass-shift detection.
Dilithium salt form, compatible with aqueous buffers.
High purity (~95.7%) suitable for analytical and molecular biology use.
Supplied in a 10 mg vial for small-scale experiments.
Useful as a stable labeled standard for qPCR, sequencing, and method validation.
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2'-Deoxyuridine is a brain-penetrant pyrimidine nucleotide associated with nervous system diseases. It can increase chromosome breakage and reduce thymidylate synthetase activity. This compound serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has demonstrated the ability to lessen microglial activation and enhance oxidative stress damage by modulating glycolytic metabolism in brain injury models, indicating its potential for Alzheimer's disease research.
Brain-penetrant pyrimidine nucleotide.
Associated with nervous system diseases.
Can increase chromosome breakage.
Reduces thymidylate synthetase activity.
Precursor in synthesis.
Analogue of other compounds.
Reduces microglial activation.
Improves oxidative stress damage.
Modulates glycolytic metabolism in brain injury.
Promising for Alzheimer's disease research.
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A thymidine nucleoside derivative commonly used to identify proliferating cells; intraperitoneal injection of BrdU can be used in combination with neuronal markers to detect adult neurogenesis in animal models; commonly used as a marker of proliferation of cancer cells in vitro
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4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analog supplied as a light-yellow solid and used as a research reagent in studies of DNA synthesis, nucleoside metabolism, and antitumor mechanisms. It is characterized for biochemical and cell-based experiments and provided with supporting analytical data.
High purity (99.8%) for research applications.
Sulfur-substituted nucleoside for incorporation and metabolism studies.
Stable solid form with recommended low-temperature storage.
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2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite and a deoxynucleotide building block of DNA. It acts as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
Endogenous metabolite
Deoxynucleotide building block for DNA
Substrate for UMP/CMP kinase
Supports DNA biosynthesis
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A nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry; can be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition
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2'-Deoxyuridine-1′-13C is a 13C-labeled isotopologue of 2'-deoxyuridine supplied as a research reagent and analytical standard for metabolite and isotope-labeling studies. It is provided as a powder with high chemical purity and defined storage recommendations.
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