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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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Uridine-5'-diphosphoglucose pyrophosphorylase is an enzyme involved in the catalysis of UDP-glucose synthesis. It can also be utilized to determine the concentration of pyrophosphate in urine.
Enzyme for UDP-glucose synthesis
Assists in pyrophosphate determination in urine
Related to glycobiology
Recombinant enzyme
Associated with metabolic disease
Metabolic enzyme/protease
Endogenous metabolite
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Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond. It is for research use only.
Nucleoside compound.
High purity: 99.97%.
Inhibits the proliferation of leukemia cell HL-60 and induces differentiation in vitro.
Alleviates CCl4-induced liver fibrosis and inhibits pro-inflammatory cytokines and NF-κB signaling pathway activation in mouse models.
Exhibits anti-ischemic, antioxidant, and anti-arrhythmic effects in rat models of acute myocardial ischemia and ischemia/reperfusion injury.
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GTP-14564 is a tyrosine kinase inhibitor targeting internal tandem duplication (ITD) and FLT3, which inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Targets internal tandem duplication (ITD) and FLT3.
Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Used in cancer targeted therapy.
Functions as an inhibitor of Fms-like tyrosine kinase 3 (FLT3).
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Uridine 5'-monophosphate-d11 dilithium is a deuterium-labeled nucleotide provided as the dilithium salt for use as an internal standard or tracer in analytical and metabolic studies. It is intended for precise mass-spectrometry quantification and research applications; store frozen for stability.
Deuterium-labeled analogue for mass spectrometry tracing.
Dilithium salt form for improved handling and solubility.
High chemical purity (99.9%).
Supplied as a research-grade micro quantity (1 mg).
Stable when stored at -20°C for up to 2 years.
Suitable as an internal standard in LC-MS/MS workflows.
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3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound demonstrates moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
Derivative of guanosine.
Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
Useful for studying guanosine receptor mechanisms.
Useful for studying purine metabolism.
Displaces 50 nM [3H]-guanosine binding to rat brain membranes.
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Uridine triphosphate trisodium dihydrate is the trisodium salt dihydrate form of UTP used as a nucleotide triphosphate donor in biochemical and molecular biology applications. It is supplied as a white to off-white solid and is commonly used in enzymatic assays, RNA synthesis, and other nucleotide-dependent reactions.
High purity (97.0%).
Chemical formula C9H16N2Na3O17P3; molecular weight 586.12 g/mol.
White to off-white solid, convenient for weighing and dissolution.
Suitable as a nucleotide triphosphate donor in enzymatic assays and RNA synthesis.
Store sealed at -20°C and protect from moisture.
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Uridine triphosphate-d13 (UTP-d13 dilithium Uridine 5 -triphosphate-d13) dilithium is deuterium labeled Uridine triphosphate (HY-107372) Uridine triphosphate (UTP Uridine 5 -triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion proliferation channels transporters and intracellular signaling under normal and disease states
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