Nucleosides and Analogues
Medchemexpress LLC 3'-Deoxycytidine | 7057-33-2 | 98.0% | 227.22 | 50 MG
4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (3'-Deoxycytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
- Functions as a purine nucleoside analogue.
- Demonstrates broad antitumor activity.
- Targets indolent lymphoid malignancies.
- Inhibits DNA synthesis.
- Induces apoptosis.
Medchemexpress LLC ATP Citrate Lyase Antibody (YA596) | 121 kDa | 50 UL
This ATP Citrate Lyase Antibody (YA596) is a rabbit-derived, non-conjugated antibody, reactive with human and mouse samples. Supplied as a liquid at 1 mg/mL concentration, it exhibits an observed molecular weight of 121 kDa and is formulated for stability. It is suitable for various immunological applications including WB, ICC/IF, IHC-P, IP, and FC.
- Host species: Rabbit
- Reactivity: Human, mouse
- Clonality: YA596 (monoclonal)
- Concentration: 1 mg/mL
- Molecular weight: 121 kDa (predicted and observed)
- Formulation: Liquid in 1*TBS (pH7.4) with 0.05% BSA, 40% glycerol, and 0.05% sodium azide
- Storage conditions: Stable for 1 year at -20°C; avoid freeze/thaw cycles
- Applications: WB, ICC/IF, IHC-P, IP, FC
eMolecules 39925-19-4 | Medchem Express | Ribavirin carboxylic acid | 5mg | 713704925 | HY-145991 | 245.191 | C8H11N3O6
Medchem Express | TRPC6-IN-1 | 5mg | 536983777 | HY-101547 | 901715-05-7 | 398.438 | C21H23FN4O3
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![Alkali Scientific NAD [β NAD] [β Nicotinamide Adenine Dinucleotide, Oxidized free acid hydrate], 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661414.jpg-250.jpg)
Alkali Scientific NAD [β NAD] [β Nicotinamide Adenine Dinucleotide, Oxidized free acid hydrate], 25 G
NAD (β Nicotinamide Adenine Dinucleotide, Oxidized form) is a vital coenzyme used in a wide range of biochemical research applications. This product is available in its oxidized free acid form, with a concentration of 25g. NAD is essential in redox reactions, where it acts as an electron carrier during cellular processes such as glycolysis and oxidative phosphorylation. It also plays a key role in DNA repair, gene expression regulation, and cell metabolism. NAD is used in laboratory experiments studying cellular respiration, aging, and diseases associated with mitochondrial dysfunction. Its diverse applications make it a fundamental tool for researchers studying metabolic pathways and cellular energy regulation.
Selleck Chemical LLC Nicotinamide S1899-10mM/1mL
Nicotinamide a water-soluble vitamin is an active component of coenzymes NAD and NADP and also act as an inhibitor of sirtuins
![Alkali Scientific AMP [Adenosine 5 Monophosphate, Free Acid], 10 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660619.jpg-250.jpg)
Alkali Scientific AMP [Adenosine 5 Monophosphate, Free Acid], 10 Grams
Adenosine 5' Monophosphate (AMP), Free Acid, is a biochemical reagent used in various laboratory applications. This 10 g package is suitable for small-scale experiments, offering a high-quality, pure form of AMP that is essential for biochemical assays and nucleic acid research. AMP plays a crucial role in cellular metabolism and is widely used in ATP production studies, enzyme kinetics, and RNA synthesis. This reagent is particularly useful in molecular biology, pharmacology, and biochemistry, where AMP is involved in various signaling pathways and enzymatic reactions. The product is ideal for researchers looking for consistency and reliability in their experimental setups.
Cambridge Isotope Laboratories 8-Hydroxy-2-deoxyguanosine (15N5 98%) 25 ug/mL in water 1 2 mL
8-Hydroxy-2-deoxyguanosine (15N5 98%) 25 ug/mL in water 1 2 mL
Medchemexpress LLC Uridine 5'-monophosphate disodium salt | 3387-36-8 | 99.9% | 368.14 | 1 ML
Uridine 5'-monophosphate disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator. It has a protective effect on the heart, promotes the synthesis of CDP-choline, and induces apoptosis in intestinal epithelial cells, benefiting gut development and reducing diarrhea.
- Promotes late apoptosis in intestinal epithelial cells.
- Beneficial for gut development and reduces diarrhea.
- Enhances synthesis of CDP-choline in the brain.
- Offers cardioprotective properties, preventing ischemic injury and arrhythmias.
Selleck Chemical LLC Nicotinamide Riboside Chloride S2935-1g
Nicotinamide Riboside Chloride is the chloride salt form of nicotinamide riboside(NR) NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride Nicotinamide riboside chloride increases NAD[ ] levels and activates SIRT1 and SIRT3 culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities Nicotinamide riboside chloride is used in dietary supplements
Medchemexpress LLC 3′-Deoxyuridine | 7057-27-4 | 98.0% | 228.20 | 25 MG
3′-Deoxyuridine is a potential anticancer and antiviral agent that inhibits bovine diarrhoea virus (BVDV) production. It is for research use only and appears as a white to light yellow solid.
- Potential anticancer agent
- Potential antiviral agent
- Inhibits bovine diarrhoea virus (BVDV) production
- For research use only
- Appearance: Solid
- Color: White to light yellow
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
- Increases telomere dysfunction in tumor cells in vivo
- Appearance: Solid
- Color: White to yellow
Selleck Chemical LLC Lamivudine S1706-1g
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor used for treatment of chronic HBV and HIV/AIDS It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase
Cambridge Isotope Laboratories 2-Deoxycytidine (15N3 96-98%) 5 mg
2-Deoxycytidine (15N3 96-98%) 5 mg