Antineoplastic bifunctional, DNA alkylating agent that causes DNA damage by cross-linking DNA and proteins. Causes double-base lesions mainly at 5’-GA-3’ and, to a lesser extent, at 5’-GG-3’ sequences. Forms an intrastrand cross-link at the 5’-GA-3’ sequence, in addition to monoalkylation. Selectively induces normal human fibroblast senescence through Erk and p38 pathways. Alternative name: 1,4-Butanediol dimethanesulfonate. Purity: ≥98% (Assay). Solubility: Soluble in acetone, 100% ethanol or DMSO; insoluble in water. Long Term Storage: -20°C.