Chromatography Standards
Enzo Life Sciences Clozapine, (50mg), CAS Number: 5786-21-0
Dopamine receptor and serotonin receptor antagonist. Dopamine D4 and D2 receptor antagonist. High affinity for the cloned rat dopamine D4 receptor (Ki2A, 5HT2C, 5HT3, 5HT6 and 5HT7 receptors. Alternative Name: 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e]-[1,4]diazepine. Formula: C18H19ClN4. MW: 326.8. CAS Number: 5786-21-0. MI: 14: 2423. Purity: ≥99% (HPLC). Appearance: Yellow crystalline powder. Solubility: Soluble in DMSO (30mg/ml) or dilute aqueous acid. Long Term Storage: +4°C
TARGETMOL CHEMICALS INC Taprenepag 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM). Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. Purity 99.32%
Medchemexpress LLC N-ethoxycarbonyl dabigatran ethyl ester | 1416446-40-6 | 10mg
Dabigatran impurity 80 is an impurity of Dabigatran (HY-10163)
Selleck Chemical LLC Docetaxel 10mM/1mL 114977-28-5 RP56976, NSC 628503
Docetaxel (RP56976, NSC 628503), an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Sumatriptan succinate | 103628-48-4 | 99.9% | 1 ML
Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist that can be used for migraine headache research. It acts on 5-HT1D, 5-HT1B, and 5-HT1F receptors with IC50 values of 7.3 nM, 9.3 nM, and 17.8 nM respectively.
- Orally active 5-HT1 receptor agonist
- Targeting 5-HT1D, 5-HT1B, and 5-HT1F receptors
- Suitable for migraine headache research
Medchemexpress LLC N-(3-chloro-2-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine | 1454307-45-9 | 50mg
Dacomitinib impurity 14 is an impurity of Dacomitinib (HY-13272)
Sigma Aldrich Fine Chemicals Biosciences Ropivacaine Related Compound B United States Pharmacopeia (USP) Reference Standard | 112773-90-7 (anhydrous) | 50MG
Ropivacaine Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 331.02 | 112773-90-7 (anhydrous) | 50MG
Medchemexpress LLC Pantoprazole | 102625-70-7 | 99.95% | 383.37 | 1 ML
Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI). It is a substituted benzimidazole and a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and possesses anti-secretory and anti-ulcer activities. It also significantly increased tumor growth delay when combined with Doxorubicin.
- Orally active and potent proton pump inhibitor (PPI)
- Substituted benzimidazole
- Potent H+/K+-ATPase inhibitor with an an IC50 of 6.8 μM
- Improves pH stability
- Anti-secretory and anti-ulcer activities
- Increased tumor growth delay in combination with Doxorubicin
Medchemexpress LLC Naloxone | 465-65-6 | 99.7% | 327.37 | 200 MG
Naloxone is an opioid receptor antagonist that alleviates opioid-overdose-induced respiratory depression. It may cause pulmonary edema and cardiac arrhythmias and is intended for research use only, not for sale to patients.
- Antagonist of opioid receptors
- Alleviates respiratory depression
- Soluble in DMSO (100 mg/mL)
- Stable at 4°C, protected from light, under nitrogen
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Suitable for in vitro and in vivo research applications
- Demonstrates activity in CHO and HEK293 cells
- Effective in animal models, including rats and cats
Sigma Aldrich Fine Chemicals Biosciences Entecavir monohydrate United States Pharmacopeia (USP) Reference Standard | 209216-23-9 | 200MG
Entecavir monohydrate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 295.29 | 209216-23-9 | 200MG
Apexbio Technology LLC Cabozantinib malate (XL184) 1140909-48-3 100mg
Cabozantinib malate (XL184 CAS 1140909-48-3) is a small-molecule inhibitor targeting multiple receptor tyrosine kinases notably MET and VEGFR2 with reported IC50 values of 1 3 nM and 0 035 nM respectively It also inhibits additional kinases including RET FLT3 KIT AXL and TEK In cellular assays Cabozantinib shows inhibition of phosphorylation in kinases MET VEGFR2 KIT FLT3 and AXL Moreover Cabozantinib suppresses HMVEC cell-tube formation (IC50 6 7 nM) and attenuates hepatocyte growth factor-induced tumor cell invasion and migration This compound has demonstrated antiproliferative activity in several cancer cell lines supporting its application in oncology research environments
Apexbio Technology LLC Esomeprazole Magnesium 161973-10-0 10mM (in 1mL DMSO)
Esomeprazole Magnesium is a small-molecule inhibitor targeting the H /K -ATPase enzyme on gastric parietal cells It is designed to inhibit this proton pump thereby reducing gastric acid secretion Esomeprazole Magnesium exerts its biological activity primarily through selective and irreversible binding to H /K -ATPase inhibiting the final step in gastric acid secretion Based on these pharmacological properties Esomeprazole Magnesium holds research potential in studies of gastric acidity regulation gastroesophageal reflux disease (GERD) inflammation-related mucosal damage and investigations of pharmacokinetics and pharmacodynamics of proton pump inhibitors
Medchemexpress LLC Gefitinib impurity 2 | 246512-44-7 | MFCD26395622 | 99.6% | 309.37 g/mol | C15H23N3O4 | 10 MG
Gefitinib impurity 2 is a characterized reference impurity of the EGFR inhibitor gefitinib intended for research and analytical use. It is supplied as a solid and as DMSO solutions, and is provided with measured purity and recommended storage conditions to support stability during handling and analysis.
- High purity: 99.56%.
- Molecular formula: C15H23N3O4.
- Molecular weight: 309.37 g/mol.
- Appearance: off-white to pink solid.
- Available formats: 10 mg solid, 5 mg solid, 10 mM 1 mL DMSO solution.
- Storage recommendations: powder at -20 °C for long term; in solvent at -80 °C for extended stability.