Organometallic Compounds
Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 50 MG
N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Azide-PEG5-Boc | 1415800-41-7 | C17H33N3O7 | 100 MG
Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Compatible with molecules containing Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Compatible with molecules containing DBCO or BCN groups
Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 250 MG
BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands
- One ligand for E3 ubiquitin ligase
- Other ligand for target protein
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules ChemScene Amino-PEG3-C2-Azido 100mg 844794569 CS-0040368 0 000 134179-38-7 MFCD00269874 218 257 C8H18N4O3
ChemScene Amino-PEG3-C2-Azido 100mg 844794569 CS-0040368 0 000 134179-38-7 MFCD00269874 218 257 C8H18N4O3
Medchemexpress LLC 2-(2-(2-Bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | 291.16 | 25 MG
Br-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Protacs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase.
- The other ligand is for the target protein.
- Protacs exploit the intracellular ubiquitin-proteasome system.
- Selectively degrade target proteins.
Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 250 MG
N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Enables targeted protein degradation via the ubiquitin-proteasome system
- Facilitates connection between an E3 ubiquitin ligase ligand and a target protein ligand
Medchemexpress LLC DNP-PEG3-azide | 951671-87-7 | 99.2% | C14H20N6O7 | 500 MG
DNP-PEG3-azide is a PEG-based PROTAC linker that functions as a click chemistry reagent due to its Azide group. It is utilized in the synthesis of PROTACs, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Reacts with alkyne-containing molecules
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Reacts with molecules possessing DBCO or BCN groups
Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | 644.63 g/mol | C28H36N8O10 | 10 MG
Folate-PEG3-C2-acid is the acid fragment of a folate-PEG3-based NHS ester and serves as a PEG-type PROTAC linker building block used in the synthesis of PROTAC molecules and folate-conjugated ligands for receptor-targeting studies.
- Purity: 97.6%.
- Molecular weight: 644.63 g/mol.
- Solubility: soluble in DMSO at 33.33 mg/mL (51.70 mM); ultrasonication and heating may aid dissolution.
- Storage: store at 4°C protected from light; in solvent keep at -80°C (6 months) or -20°C (1 month), protected from light.
- Physical state: light yellow to yellow solid.
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 1 G
Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Can be used in the synthesis of PROTACs
- Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 50 G
Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
Medchemexpress LLC M-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 10 G
m-PEG5-Br is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting the protein of interest. These compounds function by exploiting the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
Medchemexpress LLC N-(Azido-PEG3)-N-Boc-PEG4-Boc | 2112731-94-7 | C28H54N4O11 | 100 MG
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker. It is a click chemistry reagent that contains an Azide group.
- Can be used in the synthesis of PROTACs.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 5 G
Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports. PROTACs consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, and they exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- PROTACs degrade target proteins using the ubiquitin-proteasome system.
Medchemexpress LLC Nh-bis(peg3-boc) | 1814901-03-5 | 98.0% | C26H51NO10 | 100 MG
This compound serves as a PEG-based linker for assembling Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed with two distinct ligands connected by such a linker: one targets an E3 ubiquitin ligase, and the other binds to a specific target protein. This design enables PROTACs to leverage the cell's ubiquitin-proteasome system for the targeted degradation of proteins.
- Functions as a linker for PROTACs.
- Utilizes the ubiquitin-proteasome system.
- Enables targeted protein degradation.
Medchemexpress LLC NH-bis(PEG3-Boc) | 1814901-03-5 | 98.0% | C26H51NO10 | 50 MG
NH-bis(PEG3-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules connect two different ligands: one for an E3 ubiquitin ligase and another for a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- PEG-based linker
- Essential for PROTAC synthesis
- Enables targeted protein degradation