Glycosyl compounds
Medchemexpress LLC Sapintoxin D | 80998-07-8 | 99.9% | 539.62 g/mol | C30H37NO8 | 5 MG
Sapintoxin D is a fluorescent phorbol ester used as a calcium-dependent activator of protein kinase C (PKC) for biochemical and cell-based research. It enables study of PKC activation, membrane translocation, and downstream phosphorylation events in signaling pathways, and is provided as a high-purity research reagent.
- Fluorescent phorbol ester useful for visualization in assays
- Calcium-dependent activation of protein kinase C
- High purity suitable for research applications
- Molecular formula C30H37NO8 and molecular weight 539.62 g/mol
- Available in small milligram quantities for assay flexibility
- Applicable to biochemical and cell-based PKC signaling studies
Medchemexpress LLC Ophiopogonin D | 945619-74-9 | 855.02 | 10 MM * 1 ML
Ophiopogonin D is a naturally occurring C29 steroidal glycoside isolated from *Ophiopogon japonicus*. It acts as a CYP2J3 inducer and shows protective effects against inflammatory, metabolic, and cardiovascular diseases.
- Inhibits Ang II induced NF-κB nuclear translocation.
- Increases expression of CYP2J2/EETs and PPARα in HUVECs.
- Inhibits osteoclastic differentiation in RAW264.7 cells.
- Protects against H2O2-induced endothelial injury as an antioxidant.
- Blocks ERK signaling cascades.
- Alleviates high-fat diet-induced metabolic syndrome.
Cambridge Isotope Laboratories Glycan-FX1 (galactose-13C6 99%) 500 pmol
Glycan-FX1 (galactose-13C6 99%) 500 pmol
Medchemexpress LLC Fulvestrant 3-β-D-Glucuronide | 261506-27-8 | 94.79% | 782.89 | 1 MG
Fulvestrant 3-β-D-Glucuronide is a metabolite derived from Fulvestrant, a pure anti-estrogenic steroid. It is characterized as a glucuronide and sulfate conjugate. This compound is primarily intended for breast cancer research.
- Derived from an anti-estrogenic steroid.
- Exists as glucuronide and sulfate conjugates.
- Applicable in breast cancer research.
- Solid appearance, white to off-white in color.
- High purity of 94.79%.
Medchemexpress LLC TNF-alpha/TNFSF2 Mo 100ug
Recombinant mouse TNF-alpha (amino acids D89-L235; 147 aa) supplied as a 100 μg lyophilized powder for research use. The protein is produced in E. coli, provided at >95% purity, and characterized for bioactivity in cytotoxicity assays; recommended storage and reconstitution guidance is included with the product.
- Recombinant mouse TNF-alpha fragment (147 amino acids D89-L235).
- Produced in E. coli expression system.
- Supplied as a lyophilized powder for stability.
- Purity greater than 95% by reducing SDS-PAGE.
- Predicted molecular mass approximately 16.4 kDa.
- Bioactive in L-929 cytotoxicity assay; ED50 1.616 pg/mL.
- Store at -20°C; aliquot to avoid repeated freeze-thaw.
Cambridge Isotope Laboratories NAT (N-nitrosoanatabine) (13C6 99%) 100 ug/mL in acetonitrile 1 2 mL
NAT (N-nitrosoanatabine) (13C6 99%) 100 ug/mL in acetonitrile 1 2 mL
Cambridge Isotope Laboratories 2 mM Sucrose 0 5 mM DSS 2 mM NaN3 in 90% H2O/10% D2O H2O D2O v/v 1 5mm tube
2 mM Sucrose 0 5 mM DSS 2 mM NaN3 in 90% H2O/10% D2O H2O D2O v/v 1 5mm tube
Medchemexpress LLC D-(+)-Trehalose dihydrate | 6138-23-4 | 378.33 | 50 MG
D-(+)-Trehalose dihydrate is an analytical standard primarily used in research and analytical applications. Derived from Saccharomyces cerevisiae, it serves as a reference standard for qualitative, quantitative, and methodological research experiments, including techniques like HPLC, GC, and MS. This compound also finds use as a food ingredient and pharmaceutical excipient.
- For research and analytical applications.
- Functions as an analytical standard.
- Can be used as a food ingredient and pharmaceutical excipient.
- Suitable for HPLC, GC, and MS research.
Medchemexpress LLC D-64131 | 74588-78-6 | C16H13NO2 | 1 ML
D-64131 is an orally active tubulin inhibitor that demonstrates antimitotic activity by binding to β-tubulin, destabilizing microtubules, and arresting mitotic cells in the M-phase. This compound effectively inhibits the proliferation of tumor cells from various organs and tissues, making it a subject of cancer research.
- Orally active compound
- Inhibits tubulin polymerization
- Exhibits antimitotic effects
- Shows antiproliferative activity against tumor cells
- Effective against multidrug-resistant tumor cell lines
Cambridge Isotope Laboratories Glycan-F40 (galactose-13C6 99%) 500 pmol
Glycan-F40 (galactose-13C6 99%) 500 pmol
Cambridge Isotope Laboratories PAH Two Component Mixture (D 98%) 2000 ug/mL in 80% isooctane/20% toluene 1 2 mL
PAH Two Component Mixture (D 98%) 2000 ug/mL in 80% isooctane/20% toluene 1 2 mL
Medchemexpress LLC 2-(5-Phenyl-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)-N-(5-phenylpyridin-2-yl)acetamide | 2074607-48-8 | 99.8% | 432.48 g·mol⁻1 | C26H20N6O | 25 MG
A potent small-molecule Porcn inhibitor for research use that blocks Wnt protein secretion and downstream signaling. It exhibits an EC50 of 80 pM in L-Wnt-STF cells and suppresses phosphorylation of Dvl2/3 and LRP6 in cell-based assays. Supplied as a high-purity solid or as a 10 mM solution in DMSO for experimental convenience.
- Potent Porcn inhibition with an EC50 of 80 pM in L-Wnt-STF cells.
- Blocks secretion of Wnt proteins and downstream signaling pathways.
- Suppresses phosphorylation of Dvl2/3 and LRP6 in cell-based assays.
- High purity (≈99.8%) suitable for biochemical and cellular studies.
- Available as solid quantities (including 25 mg) and as a 10 mM solution in DMSO.
- Recommended storage: solid at 4°C; in solvent at -80°C for long-term stability.
Medchemexpress LLC D-α-Hydroxyglutaric acid | 13095-47-1 | 98.0% | 148.11 | 1 ML
D-α-Hydroxyglutaric acid is the primary metabolite that accumulates in the neurometabolic disorder D-2-hydroxyglutaric aciduria. It acts as a weak competitive antagonist of α-ketoglutarate (α-KG), inhibiting multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. This compound increases reactive oxygen species (ROS) production, binds to and inhibits ATP synthase, and suppresses mTOR signaling. It also accumulates in human cancers with neomorphic mutations in IDH1 and IDH2 genes.
- Weak competitive antagonist of α-ketoglutarate (α-KG).
- Inhibits multiple α-KG-dependent dioxygenases.
- Increases reactive oxygen species (ROS) production.
- Binds to and inhibits ATP synthase.
- Suppresses mTOR signaling.
- Accumulates in human cancers with IDH1 and IDH2 gene mutations.
AdipoGen MEGA-8 ultrapure
Chemical. CAS 85316-98-9. Formula C15H31NO6. MW 321.4. Non-ionic water-soluble detergent with nondenaturing properties. Transparent in the UV region. Relatively high critical micelle concentration CMC value 79mM/l. Ideal for studying the conformation and function of proteins, keeping the secondary and tertiary structure intact, therefore suited for solubilizing membrane proteins without altering biological activity. Efficiently separates hydrophilic proteins from membrane spanning, hydrophobic proteins. Ideal for use as membrane protein solubilizer.
Sigma Aldrich Fine Chemicals Biosciences D-(+)-Cellobiose suitable for microbiology, >=99.0% | 528-50-7 | MFCD00136034 | 50G
D-(+)-Cellobiose suitable for microbiology, >=99.0% | Purity: >=99.0% (HPLC); >=99.0% | Mol Wt: 342.3 | 528-50-7 | MFCD00136034 | 50G