Monosaccharides
Medchemexpress LLC Adenylyl-imidodiphosphate disodium | 7414-56-4 | MFCD32646673 | 99.4% | 549.17 | C11H16N5Na2O12P3 | 10 MG
AMP-PCP disodium is a non-hydrolyzable ATP analogue (adenylyl-imidodiphosphate disodium) used to mimic ATP binding in biochemical and structural studies. It binds the N-terminal domain of Hsp90 with a reported Kd of 3.8 μM and favors formation of the active Hsp90 homodimer, making it useful for probing ATP-dependent enzyme mechanisms and protein complex assembly.
- Non-hydrolyzable ATP analogue for stabilizing ATP-bound states.
- Binds Hsp90 N-terminal domain (Kd ≈ 3.8 μM), facilitating homodimer formation.
- Provided as the disodium salt with high purity (99.4%).
- High aqueous solubility: H2O 100 mg/mL; PBS 50 mg/mL (ultrasonic recommended).
- Storage recommendations: solid -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Supplied in small research pack sizes suitable for biochemical assays.
Medchemexpress LLC Retagliptin phosphate (SP2086 phosphate) | 1256756-88-3 | 99.7% | 562.36 | 50 MG
Retagliptin phosphate (SP2086 phosphate) is a selective, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It can be used for type 2 diabetes mellitus (T2DM) research.
- Selective, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor.
- Used for type 2 diabetes mellitus (T2DM) research.
Apexbio Technology LLC EPRODISATE-DISODIUM-500MG
Eprodisate disodium (CAS No 36589-58-9) is a compound studied primarily within the field of biomedical research It originates as a synthetic molecule designed for therapeutic intervention in amyloid-related diseases Eprodisate disodium functions by inhibiting the polymerization of amyloid fibrils specifically targeting the interaction between amyloid proteins and glycosaminoglycans which are crucial pathways in disease progression Its activity is commonly observed in the nanomolar to low micromolar range indicating potent efficacy The compound is frequently utilized in cell models and animal studies for investigating amyloid inhibition and can be instrumental in drug screening processes Experimental concentrations typically depend on the specific research design Such studies aim to validate its potential as a therapeutic agent enhancing the understanding of diseases characterized by amyloid accumulation
Apexbio Technology LLC Balsalazide-disodium-diH2O
Balsalazide disodium dihydrate (CAS No 150399-21-6) is a prodrug commonly used in biomedical research focused on gastrointestinal conditions like ulcerative colitis Originating from efforts to reduce inflammation its mechanism involves releasing the active 5-aminosalicylic acid (5-ASA) in the colon which inhibits the production of inflammatory mediators such as leukotrienes and prostaglandins In vitro it shows activity in the nanomolar to low micromolar range indicating its efficacy in modulating inflammatory pathways Typical applications include studies using cell models like colon epithelial cells and animal studies aimed at understanding its therapeutic potential It is also explored in drug screening for new anti-inflammatory agents Experimental concentrations typically depend on the specific research design allowing flexibility in dosage depending on the experimental setup and objective
