Monosaccharides
Medchemexpress LLC L-(+)-arabinose | 5328-37-0 | MFCD00135866 | 100.0% | 150.13 g/mol | C5H10O5 | 25 MG
L-(+)-Arabinose is an analytical reference standard of the naturally occurring pentose sugar L-arabinose, intended for research and analytical use including assay calibration, method development, and chromatographic reference. It is supplied as a white to off-white crystalline powder with high chemical purity suitable for laboratory applications.
- Purity 99.95%.
- Molecular weight 150.13 g/mol.
- Chemical formula C5H10O5.
- Supplied as a white to off-white crystalline powder.
- Pack sizes: 25 mg, 50 mg, 100 mg, 250 mg.
- Intended for analytical reference, assay calibration, and method validation.
- Certificate of analysis available for individual batches.
Medchemexpress LLC Baricitinib phosphate | 1187595-84-1 | MFCD25976707 | 100.0% | 469.41 g/mol | C16H20N7O6PS | 10 MG
Baricitinib phosphate is the phosphate salt form of baricitinib, a selective, orally bioavailable inhibitor of JAK1 and JAK2 with low-nanomolar potency. It is supplied as a solid research reagent intended for in vitro and in vivo studies probing JAK-mediated signaling.
- Selective inhibitor of JAK1 and JAK2 (IC50: JAK1 5.9 nM; JAK2 5.7 nM; TYK2 53 nM; JAK3 560 nM).
- Molecular formula C16H20N7O6PS and molecular weight 469.41 g/mol.
- CAS number 1187595-84-1.
- Purity 99.97% as listed by manufacturer.
- High solubility in DMSO (250 mg/mL; 532.58 mM); in vivo formulations show solubility ≥2.08 mg/mL (4.43 mM).
- Appearance white to yellow solid suitable for research use.
- Store sealed at 4°C; in solvent store at -80°C (1 year) or -20°C (6 months).
Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 50 MG
K-Ras ligand-Linker Conjugate 4 integrates a ligand for K-Ras recruiting moiety and a PROTAC linker, which recruits E3 ligases (VHL, CRBN, MDM2, IAP). It is used in the synthesis of a potent PROTAC K-Ras degrader that demonstrates ≥70% degradation efficacy in SW1573 cells. PROTACs utilize the intracellular ubiquitin-proteasome system for selective degradation of target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- Incorporates a ligand for K-Ras recruiting moiety.
- Features a PROTAC linker to recruit E3 ligases.
- Used in the synthesis of potent protein degraders.
- Facilitates selective degradation of target proteins.
- Leverages the ubiquitin-proteasome system.
Medchemexpress LLC NSC-87877 (disodium) | 56932-43-5 | 503.42 | 25 MG
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1). This compound also inhibits dual-specificity phosphatase 26 (DUSP26).
- Potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases
- Exhibits IC50 values of 0.318 μM for Shp2
- Exhibits IC50 values of 0.355 μM for Shp1
- Inhibits dual-specificity phosphatase 26 (DUSP26)
Medchemexpress LLC Baricitinib phosphate | 1187595-84-1 | C16H20N7O6PS | 500 MG
Baricitinib phosphate is a selective, orally bioavailable inhibitor targeting JAK1 and JAK2 pathways. It demonstrates potent inhibition of JAK signaling and function in various cellular assays, making it suitable for research applications.
- Selective JAK1/JAK2 inhibitor with high potency
- Inhibits IL-6-stimulated STAT3 phosphorylation and MCP-1 production in PBMCs
- Inhibits pSTAT3 stimulated by IL-23 in isolated naive T-cells
- Prevents IL-17 and IL-22 production by Th17 cells
- Demonstrates anti-inflammatory effects in vivo, reducing hind paw swelling and immune cell infiltration
Medchemexpress LLC Glucose-6-phosphate dehydrogenase | 9001-40-5 | 108.6 kDa | 5KU
Glucose-6-phosphate dehydrogenase (G6PD) from a microorganism is the rate-limiting enzyme of the pentose phosphate pathway. Supplied as an enzymatic preparation (5 KU), it generates NADPH for biochemical and enzymatic assays and is intended for research applications including metabolic studies, antioxidant pathway analysis, and disease models such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy. Refer to the product data sheet and certificate of analysis for purity, storage, and handling instructions.
- Rate-limiting enzyme of the pentose phosphate pathway.
- Provides NADPH for antioxidant and metabolic assays.
- Enzyme activity ≥150 U/mg (solid).
- Specific activity ≥500 U/mg (protein).
- Unit definition: 1 μmol D-glucose 6-phosphate oxidized per min at pH 7.8, 37°C.
- Pack size: 5 KU.
- Source organism: microorganism.
- Purity and storage details available in data sheet and certificate of analysis.
Medchemexpress LLC EDTA disodium manga 1kg
Disodium manganese EDTA is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Pemetrexed disodium hemipenta hydrate | 357166-30-4 | 99.78% | 516.41 | 100 MG
Pemetrexed disodium hemipenta hydrate is a CNS-penetrant antifolate. Its pentaglutamate form inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). This product is intended for research use only.
- CNS-penetrant antifolate
- Inhibits thymidylate synthase (TS)
- Inhibits dihydrofolate reductase (DHFR)
- Inhibits glycinamide ribonucleotide formyltransferase (GARFT)
- Antitumor activity through inhibition of multiple key folate-requiring enzymes
- Substrate for the enzyme FPGS
- Soluble in water
Medchemexpress LLC cGAMP disodium | 2407516-83-8 | 98.5% | 718.37 | 25 MG
cGAMP disodium | 2407516-83-8 | 98.5% | 718.37 | 25 MG
TARGETMOL CHEMICALS INC Pemetrexed disodium 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has been associated with moderate rates of serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury. Purity 99.92%
![Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 2.5 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661061.jpg-250.jpg)
Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 2.5 Kg
EDTA Disodium Salt (2.5 kg) is a high-concentration chelating agent used for laboratory experiments that require the removal or sequestration of metal ions. This 2.5 kg package is ideal for large-scale applications in biochemistry, molecular biology, and other scientific fields where metal ion control is essential. EDTA works by binding to metal ions such as calcium, magnesium, and iron, preventing them from catalyzing unwanted chemical reactions or interfering with enzymatic activity. It is widely used in DNA and RNA extraction, enzyme assays, and metal ion quantification. Laboratories that conduct frequent experiments requiring consistent metal ion control benefit from this bulk packaging.
Gold Biotechnology Inc EDTA Disodium dihydrate 500 g
EDTA (Ethylenediaminetetraacetic acid) is a chelating agent a general chemical and a sequestrant In molecular biology applications it is used to minimize metal ion contamination and prevent enzymatic activity
Medchemexpress LLC Glucose 6-phosphate dehydrogenase (yeast, recombinant) | 9001-40-5 | 500 U
Glucose 6-phosphate dehydrogenase (yeast, recombinant) is the rate-limiting enzyme of the pentose phosphate pathway and a major source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems. It helps cells resist oxidative stress and regulates metabolic rates, holding potential for research in fields such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy.
- Rate-limiting enzyme of the pentose phosphate pathway
- Major source of NADPH in antioxidant pathways
- Involved in nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems
- Helps cells resist oxidative stress
- Regulates metabolic rates
- Potential for research in diabetes, endothelial dysfunction, cancer, and cardiomyopathy
- Classified as an enzyme and recombinant biochemical
- Considered an endogenous metabolite
Medchemexpress LLC FAK ligand-Linker Conjugate 1 | 2307461-45-4 | 98.9% | 583.58 | 1 ML
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). It can be extensively used for PROTAC-mediated protein degradation.
- Incorporates a ligand for FAK.
- Includes a PROTAC linker.
- Recruits E3 ligases (VHL, CRBN, MDM2, IAP).
- Used for PROTAC-mediated protein degradation.
- For research use only.