Monosaccharides
Medchemexpress LLC Sitagliptin (phosphate) | 654671-78-0 | 99.6% | 505.31 | 1 ML
Sitagliptin (MK-0431) phosphate is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. It blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition mechanism (Kᵢ = 1 nM), thereby increasing the level of active incretin. Sitagliptin phosphate can also directly stimulate the secretion of GLP-1 by intestinal L cells by activating the cAMP/PKA and ERK1/2 pathways, independent of DPP-4. It shows protective effects on pancreatic islet grafts in type 1 diabetes models and can be used for the study of type 1 and type 2 diabetes.
- Orally active and highly selective DPP4 inhibitor
- Blocks degradation of GLP-1 and GIP
- Increases active incretin levels
- Directly stimulates GLP-1 secretion
- Protective effects on pancreatic islet grafts
- Useful for type 1 and type 2 diabetes research
Medchemexpress LLC Alpha-D-glucose hydrate | 14431-43-7 | 98% | 1 ML
alpha-D-glucose hydrate is a monosaccharide, the most common form of glucose, and cannot be broken down into simpler sugars. It plays a vital role in energy metabolism as a primary energy source for many cells and is a building block for larger carbohydrates like starch and glycogen. The α prefix indicates the orientation of the hydroxyl group on the first carbon atom, and it exists in solution as a hydrate.
- Most common form of glucose
- Plays a vital role in energy metabolism
- Primary energy source for many cells
- Building block of larger carbohydrates
- Exists in solution as a hydrate
- Biochemical reagent for life science related research
- High purity of 98%
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC Penta-O-acetyl-β-D-glucopyranose | 604-69-3 | 98.0% | 390.34 | 100 G
β-D-Glucose pentaacetate is a glucose derivative primarily utilized for investigating the mechanism of insulin secretion. It acts as an insulinotropic agent and is slightly less potent than α-D-Glucose Pentaacetate in stimulating insulin secretion.
- A glucose derivative.
- Primarily used to explore insulin secretion mechanisms.
- Acts as an insulinotropic agent.
- Shows cytotoxicity against various human cell lines at high concentrations (> 200 μM).
Medchemexpress LLC HA/Hemagglutinin H1 10ug
Hemagglutinin protein (HA) is a class I viral fusion protein that binds to sialic acid-containing receptors and initiates viral attachment to cells This binding promotes internalization of virions through various endocytic pathways HA/Hemagglutinin Protein H1N1 (P03452 sf9 His) is the recombinant Virus-derived HA/Hemagglutinin protein expressed by Sf9 insect cells with C-His labeled tag
Medchemexpress LLC Alpha-D-glucose (standard) | 492-62-6 | 99.9% | 25 MG
Alpha-D-glucose (Standard) is the analytical standard for alpha-D-glucose, intended for research and analytical applications. This monosaccharide has a more significant insulin stimulating effect than beta-D-glucose.
- It is an analytical standard.
- It is a reference standard supplied assay.
- It is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- It is classified as a saccharide and a monosaccharide.
- Its initial source is microorganisms.
- It is an endogenous metabolite.
- It has a purity of 99.94%.
Apexbio Technology LLC Dextrose (D-glucose) 50-99-7 10mM (in 1mL DMSO)
Dextrose (D-glucose) (CAS 50-99-7) is a monosaccharide serving as an endogenous ligand for glucose transporters (GLUTs) It facilitates cellular glucose uptake and ATP generation by acting as a primary metabolic substrate Dextrose exerts its biological activity chiefly through glycolytic metabolism supporting cell growth proliferation and survival In cell-based studies it is widely applied as a metabolic substrate in cell culture media and as glucose supplementation during cell viability assays metabolic assessments and as a reference agent in glucose uptake and insulin sensitivity investigations Dextrose itself generally lacks a defined IC50 value due to its role as a natural substrate Based on these pharmacological properties Dextrose is utilized in research on cellular metabolism viability and insulin responsiveness
Boston Bioproducts Inc 40 pct. Glucose 250ml
Glucose (40%) - 250ml (For Research Use and Further Manufacturing Only)
Medchemexpress LLC Biotin-D-Glucose | ≥90.0% | 5 MG
Biotin-D-Glucose is a biotin-conjugated glucose derivative with a molecular formula of C16H26N2O8S and a molecular weight of 406.45. It appears as a white to off-white solid and has a purity of ≥90.0%. It is intended for research use only.
- Biotin-conjugated glucose derivative
- Molecular formula: C16H26N2O8S
- Molecular weight: 406.45
- Appearance: White to off-white solid
- Purity: ≥90.0%
- Storage: -20°C, protect from light
- In solvent storage: -80°C for 6 months; -20°C for 1 month (protect from light)
- Solubility: 100 mg/mL in DMSO (requires ultrasonic)
- For research use only
Medchemexpress LLC D-Glucose 6-phosphate sodium | 54010-71-8 | 98.0% | 282.12 | 500 MG
D-Glucose 6-phosphate sodium is an endogenous metabolite. It is for research use only and serves as a human endogenous metabolite.
- Solid appearance.
- White to off-white color.
- Shipping at room temperature in continental US; may vary elsewhere.
- Storage at 4°C, stored under nitrogen.
- In solvent: -80°C for 6 months; -20°C for 1 month (stored under nitrogen).
- Soluble in H2O: 50 mg/mL (177.23 mM; requires ultrasonic).
Medchemexpress LLC D-Glucose-d7 | 66034-51-3 | 99.4% | 25 MG
D-Glucose-d7 is the deuterium-labeled form of D-Glucose, a naturally occurring monosaccharide. It serves as a critical component of general metabolism and acts as a signaling molecule related to cellular metabolic status and stress response. It is a white to off-white solid with a molecular formula of C6H5D7O6 and a molecular weight of 187.20. Storage conditions for powder are -20°C for 3 years and 4°C for 2 years, while in solvent it can be stored at -80°C for 6 months and -20°C for 1 month.
- Isotope-labeled compound for metabolic studies
- Critical component in general metabolism
- Signaling molecule for cellular metabolic status and stress response
- High isotopic enrichment of 98.2%
- Available as a white to off-white solid
Alkali Scientific Potato Dextrose Agar, 5 Kg
Potato Dextrose Agar (PDA), 5kg, is a highly effective medium for growing a wide variety of fungi, including yeasts and molds. It is particularly useful in environmental monitoring, food testing, and clinical diagnostics, where fungal isolation is needed. This medium contains dextrose as the primary carbon source and potato infusion for added nutrients, making it ideal for cultivating fungi from diverse samples. The 5kg bulk size is perfect for high-throughput laboratories or those involved in large-scale testing, offering a cost-effective solution for routine fungal cultivation, research, and microbiological analysis.
Medchemexpress LLC HA/Hemagglutinin H1 50ug
The hemagglutinin (HA) protein attaches viral particles to host cells by binding to sialic acid-containing receptors and induces viral particle internalization through clathrin-dependent endocytosis HA also promotes an alternative clathrin- and caveolin-independent pathway for some virions HA/Hemagglutinin Protein H1N1 (QEM24663 sf9 His) is the recombinant Virus-derived HA/Hemagglutinin protein expressed by Sf9 insect cells with C-His labeled tag
Medchemexpress LLC D-glucose-18O | 3343-70-2 | 99.9% | 182.16 g/mol | C6H12O6 (contains one 18O) | 10 MG
D-Glucose-18O is an oxygen-18-labeled form of D-glucose used as a stable isotope tracer in metabolic and biochemical research. It facilitates tracking of oxygen incorporation and exchange in enzymatic and metabolic pathways, and is supplied as a small, high-purity solid suitable for analytical applications.
- Stable isotope-labeled glucose for tracer studies.
- High isotopic and chemical purity for accurate mass spectrometry.
- Suitable for metabolic flux analysis and enzymology experiments.
- Convenient small-format solid for analytical preparation and standards.
- CAS number 3343-70-2; molecular weight ~182.16 g/mol.