Sugar acids and derivatives
Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | 99.99% | 338.31 | 25 MG
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU exhibits pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3). The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. This compound can be utilized as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
- Fluorescent substrate for α-glucosidase.
- Releases fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage.
- 4-MU has pH-dependent fluorescence excitation activity.
- Can be used as a biomarker for Fabry and Pompe diseases.
- Quantifies α-glucosidase activity in infant blood spot samples.
Medchemexpress LLC IFN-beta Rhesus Mac 100ug
IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway IFN-beta Protein regulates mitochondrial fission through STAT5 PGAM5 and Drp1 to rescue neurodegeneration IFN-beta Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein expressed by HEK293 with C-mFc labeled tag
Medchemexpress LLC 4-Methylumbelliferyl 10mM | 440.61 g/mol | C28H40O4 | 10MM 1ML
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases 4-Methylumbelliferyl oleate is cleaved by lipases liberating 4-Methylumbelliferyl (Ex/Em 320/450 nm)[1][2]
Medchemexpress LLC Rehmannioside D | 81720-08-3 | 686.61 | 25 MG
Rehmannioside D is a carotenoid glycoside found in root extracts of Rehmannia glutinosa. This compound exhibits antioxidant activities and can be studied in research as a supplement for pharmaceutical products.
- High purity (99.89%).
- Solid form, white to off-white in color.
- Soluble at 100 mg/mL in H2O (requires ultrasonic).
- Classified as a terpenoid and iridoid.
- Derived from the Rehmannia glutinosa plant.
- For research use only.
Medchemexpress LLC PI4KIIIbeta-IN-10 | 1881233-39-1 | 9290DU | 99.8% | 475.58 | 10 MG
PI4KIIIbeta-IN-10 is a potent and selective inhibitor of PI4KIIIβ, demonstrating an IC50 of 3.6 nM. This compound exhibits minimal off-target inhibition of related lipid kinases, showing weak inhibition of PI3KC2γ, PI3Kα, and PI4KIIIα, and less than 20% inhibition for PI4K2α, PI4K2β, and PI3Kβ at concentrations up to 20 μM. It is designed for research use only, providing a valuable tool for scientific investigations.
- Potent PI4KIIIβ inhibitor with high selectivity
- Minimal off-target activity against related lipid kinases
- Available in various quantities and formulations
- Suitable for research applications
Apexbio Technology LLC CiMigenol 3-β-D-xylopyranoside 27994-11-2 10mg
CiMigenol 3-beta-D-xylopyranoside is a triterpenoid saponin glycoside featuring a xylose sugar moiety at the 3-beta position of the CiMigenol aglycone It is investigated for its potential to modulate anti-inflammatory antioxidant and cytotoxic mechanisms thereby regulating cellular pathways involved in proliferation apoptosis and inflammatory signaling Current research explores the biological activities of CiMigenol 3-beta-D-xylopyranoside however specific experimental models mechanisms of action numerical activity metrics and direct molecular targets are not explicitly reported Based on these pharmacological properties CiMigenol 3-beta-D-xylopyranoside holds research potential in studies focused on inflammation oxidative stress and cell viability
Medchemexpress LLC MSX-122 | 897657-95-3 | 98.2% | 292.34 | 25 MG
MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ~10 nM.
- Anti-inflammatory activity.
- Anti-metastatic activity.
- Orally active.
- Potently blocks invasion of MDA-MB-231 cells in vitro.
- Blocks inflammation induced by carrageenan and lung fibrosis induced by bleomycin in mice.
- Blocks metastasis in an experimental animal model of breast cancer metastasis.
- Significantly decreases the numbers of hepatic micrometastases in vivo.