Sugar acids and derivatives
Amsbio LLC Heparan Sulfate
Major disaccharide units: GlcA-GlcNAc and IdoA/GlcA-GlcNS (variable O-sulphation). Degree of N-sulphation 65 (N-sulphates/100 disaccharides). Ratio N-sulphation:O-sulphation = 0.73. Single band on agarose gel electrophoresis. Contains both low and high sulphated heparan sulphates.
Medchemexpress LLC Integrin alpha V bet 50ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
Medchemexpress LLC Integrin alpha 5 bet 10ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
Medchemexpress LLC Integrin alpha X bet 10ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
Medchemexpress LLC Bet bromodomain inhibitor | 1505453-59-7 | MFCD28144506 | 99.5% | 445.90 g/mol | C24H20ClN5O2 | 100 MG
BET bromodomain inhibitor is a small-molecule research compound that selectively inhibits BET family bromodomains, including BRD4, with reported biochemical potency (BRD4(1) IC50 = 14 nM). It is supplied as a solid (white to off-white) with high purity for preclinical laboratory use.
- Potent BRD4 inhibitor (IC50 = 14 nM).
- High purity (~99.5%).
- Solid, white to off-white powder.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Available in small research quantities, including 100 MG packaging.
Medchemexpress LLC 4-Methylumbelliferyl 1g
4-Methylumbelliferyl octanoate is a octoate 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase[1]
Medchemexpress LLC Integrin alpha 5 bet 100ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Avi C-His labeled tag Integrin alpha 5 beta 1 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 110-140 kDa
Medchemexpress LLC JBI-589 | 2308504-22-3 | 99.8% | 481.56 g·mol⁻¹ | C29H28FN5O | 10 MG
JBI-589 is a non-covalent, isoform-selective inhibitor of peptidylarginine deiminase 4 (PAD4) with oral bioavailability, developed for preclinical cancer and immunology research. It reduces CXCR2 expression, blocks neutrophil chemotaxis, and has shown activity in reducing primary tumor growth and metastasis in experimental studies.
- Selective PAD4 inhibition with demonstrated activity in cellular assays.
- Orally bioavailable small molecule suitable for in vivo studies.
- High chemical purity for research use.
- Soluble in DMSO at high concentrations (requires sonication).
- Stable when stored under recommended powder and solvent conditions.
Medchemexpress LLC Heparin calcium | 37270-89-6 | MFCD00131296 | ≥98.0% | 3600-5000 | Not specified (heterogeneous polysaccharide; no single chemical formula) | 25 MG
Heparin calcium (MW 3600-5000) is a low-molecular-weight heparin anticoagulant supplied for research use. It binds antithrombin III to inactivate thrombin and other activated clotting factors, preventing fibrin formation. The material is provided as a white to off-white solid with good aqueous solubility and is intended for laboratory assays involving anticoagulation or coagulation pathway studies.
- Intended for research use only.
- Anticoagulant that binds antithrombin III to inhibit coagulation.
- Molecular weight range 3600-5000.
- Supplied as a white to off-white solid.
- Soluble in water (≈200 mg/mL with ultrasonication).
- Store sealed and dry at 4 °C; in solution, store at -20 °C to -80 °C per guidelines.
- Typical purity ≥98% (batch-specific certificate of analysis available).
- Available in small laboratory package sizes (example: 25 mg).
BIOHIPPO T-bet-TAG-Puro LV
T-bet-TAG-Puro is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Apexbio Technology LLC HMP Linker 68858-21-9 100g
HMP Linker is an acid-sensitive linker used in solid-phase peptide synthesis (SPPS) It is designed to facilitate the covalent attachment of peptide carboxy-terminal residues to solid-phase resin supports and enables controlled cleavage of synthesized peptides under mildly acidic conditions thereby preserving the structural integrity of sensitive functional groups and peptide termini HMP Linker acts primarily by hydrolyzing upon acid catalysis which allows the intact release of peptides from resin supports Based on these properties HMP Linker holds research potential in peptide therapeutics synthesis and studies requiring mild peptide cleavage conditions
eMolecules 6-(Methylsulfonyl)-1h-indole-2-carboxylic acid | 383132-63-6 | MFCD02664464 | 1g
Combi-Blocks | 6-(Methylsulfonyl)-1h-indole-2-carboxylic acid | 1g | 401039913 | QA-0849 | 96.000 | 383132-63-6 | MFCD02664464 | 239.250 | C10H9NO4S
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Medchemexpress LLC D-Mannoheptulose | 3615-44-9 | MFCD00006622 | 210.18 | 10 MG
D-Mannoheptulose is a 7-carbon keto sugar found in avocado. It is a specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes. This compound can block insulin release and the utilization of carbohydrates in rats. It also exhibits various functions such as antioxidant and anticancer effects, and can act as an energy source.
- Specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes
- Can block insulin release
- Can block utilization of carbohydrates in rats
- Exhibits antioxidant effects
- Shows anticancer effects
- Acts as an energy source
- Inhibits breast cancer cell line growth (MCF-7 IC50: 263.3 μg/mL)
- No significant cytotoxic effect on normal cells (HMECs IC50: 975.1 μg/mL)
Medchemexpress LLC Perindopril acyl-β-D-glucuronide | 120398-66-5 | 544.59 | 1 MG
Perindopril acyl-β-D-glucuronide is a metabolite of Perindopril, which is an ACE inhibitor. This product is intended for research purposes only.
- For research use only.
- Not for sale to patients.