Sugar acids and derivatives
BIOHIPPO T-bet-TAG-BSD LV
T-bet-TAG-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Medchemexpress LLC Integrin alpha V beta 8 protein, mouse | ≥95.0% | 20UG
Integrin alpha V beta 8 protein (mouse) is a recombinant heterodimer expressed in HEK293 cells with a C-terminal His tag, intended for research use in studies of integrin signaling, ligand binding, and cell adhesion. The product is supplied as a purified protein in defined sizes and is characterized by a reported purity and molecular weight range suitable for biochemical and cell-based assays.
- Recombinant mouse integrin heterodimer suitable for functional assays.
- Produced in HEK293 expression system to preserve mammalian modifications.
- His tag facilitates purification and detection in biochemical workflows.
- High purity supports reliable assay results (≥95.0%).
- Supplied in defined sizes for flexible experimental needs.
- Molecular weight consistent with alpha and beta subunits (80-140 kDa).
Medchemexpress LLC Integrin alpha L beta 2 protein, mouse (HEK293, His) | 95.0% | 50UG
Integrin alpha L beta 2 protein (mouse) is a recombinant heterodimeric extracellular domain co-expressed in HEK293 cells and purified with a C-terminal His tag. The preparation is supplied as a purified protein for use in biochemical and cell-based assays requiring the integrin extracellular domain, including receptor-binding and cell-adhesion studies. Molecular weights correspond to αL (160-180 kDa) and β2 (90-105 kDa); purity is typically ≥95%.
- Recombinant heterodimeric integrin representing alpha L and beta 2 subunits.
- Mouse origin, HEK293 expression for mammalian-like post-translational modifications.
- C-terminal His tag for detection and purification.
- Molecular weight: αL 160-180 kDa, β2 90-105 kDa.
- High purity, typically ≥95%.
- Suitable for receptor-binding, cell-adhesion, and signaling assays.
- Provided in a small-scale purified format for research use.
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC N-Glycolylneuraminic acid | 1113-83-3 | 99.8% | 10 MG
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule, synthesized in pigs but not in humans. It functions as a decoy receptor for N-Glycolylneuraminic acid-binding influenza A viruses (IAVs), making it suitable for research applications.
- Nonhuman sialic acid molecule
- Functions as a decoy receptor for influenza A viruses
- Prevents influenza virus entry into A549 cells in vitro studies
- Available as a white to off-white solid
- For research use only
Medchemexpress LLC Integrin alpha 8 bet 10ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Sigma Aldrich Fine Chemicals Biosciences Acetobromo alpha D glucose100G
Acetobromo alpha D glucose100G
Medchemexpress LLC BET bromodomain inhibitor | 1505453-59-7 | MFCD28144506 | 99.5% | 445.90 | C24H20ClN5O2 | 1 ML
BET bromodomain inhibitor is an orally active, selective BET-family bromodomain inhibitor used in cancer research to inhibit tumor cell proliferation, induce cell cycle arrest, and promote apoptosis. It is supplied as a solid and as a 10 mM solution in DMSO (1 mL). The compound has a molecular formula of C24H20ClN5O2 and a molecular weight of 445.90.
- Orally active, selective BET bromodomain inhibitor
- Available as a solid or 10 mM solution in DMSO (1 mL)
- Used in cell-based assays to study proliferation, cell cycle, and apoptosis
- High chemical purity suitable for research applications
- Store powder and solutions as recommended to preserve stability
Medchemexpress LLC Beta-casein phosphopeptide | 183582-09-4 | 99.19% | 2061.96 | 10 MG
beta-Casein phosphopeptide is a biologically active peptide derived from bovine beta-Casein. This monophosphopeptide (phospho-Serine) is primarily used for the characterization of affinity-purified phosphorylated peptides in liquid chromatography and for the analysis or detection of phosphorylated peptides in mass spectrometry. This product is for research use only.
- Biologically active peptide
- Used for characterization of phosphorylated peptides
- Suitable for liquid chromatography and mass spectrometry applications
- For research use only
Medchemexpress LLC Complement factor D-IN-1 | 1386455-76-0 | 98.9% | 483.32 g/mol | C21H19BrN6O3 | 25 MG
Complement factor D-IN-1 is a potent and selective reversible small-molecule inhibitor of complement factor D used in research to probe the alternative complement pathway. It exhibits low-nanomolar activity in biochemical assays and is supplied with high reported purity as a solid or as a DMSO solution.
- Potent and selective reversible inhibitor of complement factor D.
- Demonstrated low-nanomolar IC50s in FD thioesterolytic and MAC deposition assays.
- High reported purity (≈98.8%).
- Available as dry powder or as a ready-to-use DMSO solution.
- Stable when stored under recommended conditions for long-term use.
- Suitable for biochemical and cellular complement pathway studies.
Medchemexpress LLC IL-1RA/IL-1F3 Porci 5ug | 5ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free