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Filtered Search Results

Sigma Organic Chemistry Methyl heptadecanoate | 25G | 1731-92-6 | MFCD00009001
CAS #: 1731-92-6
MDL #: MFCD00009001
Purity: >95 %
UNSPSC Code: 12352100
Molecular Weight: 284.48

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Sigma Organic Chemistry Methyl hexanoate | 100ML | 106-70-7 | MFCD00009510
CAS #: 106-70-7
MDL #: MFCD00009510
Purity: >99 %
UNSPSC Code: 12352100
Molecular Weight: 130.18

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Sigma Organic Chemistry Methyl octanoate | 25G | 111-11-5 | MFCD00009551
CAS #: 111-11-5
MDL #: MFCD00009551
Purity: >99 %
UNSPSC Code: 12352100
Molecular Weight: 158.24

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Sigma Organic Chemistry Methyl butyrate | 500ML | 623-42-7 | MFCD00009391
CAS #: 623-42-7
MDL #: MFCD00009391
Purity: >99 %
UNSPSC Code: 12352100
Molecular Weight: 102.13

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Apexbio Technology LLC (±)-Octanoylcarnitine chloride 14919-35-8 100mg
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( )-Octanoylcarnitine chloride is an acyl derivative structurally related to acetylcarnitine chloride it functions as an intermediate in fatty acid metabolism by facilitating fatty acid transport across mitochondrial membranes for subsequent -oxidation and ATP synthesis Experimental evidence indicates that ( )-octanoylcarnitine modulates mitochondrial utilization of certain branched-chain 2-oxo acids influencing their oxidation rates in isolated mitochondria Additionally researchers employ ( )-octanoylcarnitine combined with malate to investigate mitochondrial respiratory activity examining oxidative phosphorylation dynamics in response to metabolic modulators such as ADP and creatine particularly in isolated cardiac muscle tissues

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Apexbio Technology LLC Solifenacin succinate 242478-38-2 10mM (in 1mL DMSO)
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Solifenacin succinate (CAS 242478-38-2) is a selective muscarinic M3 receptor antagonist derived from tetrahydroisoquinoline and quinuclidine It primarily exerts its effect by competitively blocking acetylcholine binding at M3 receptors thereby attenuating muscarinic-mediated intracellular calcium mobilization In receptor binding assays solifenacin displays highest affinity for human M3 receptors (Ki 12 nM) It also selectively inhibits carbachol-induced contractions in isolated rat bladder tissues Consequently solifenacin succinate is frequently employed in biomedical research focused on lower urinary tract physiology and disorders associated with bladder hyperactivity

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Apexbio Technology LLC Estradiol valerate 979-32-8 10mM (in 1mL DMSO)
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Estradiol valerate is a synthetic estrogen ester and agonist of estrogen receptors (ERs) As a prodrug following administration it undergoes enzymatic hydrolysis to release active estradiol thereby activating estrogen receptor-mediated signaling pathways Estradiol interactions with ER and ER receptors lead to modulation of gene transcription related to cellular growth differentiation reproductive function and endocrine regulation In biomedical research Estradiol valerate frequently serves as a representative estrogenic agent to study ER-mediated biological mechanisms hormone-dependent cellular responses and experimental hormone deficiency models such as menopausal or ovarian dysfunction contexts Common research applications include investigating cellular responses to estrogen stimulation examining reproductive biology mechanisms and evaluating therapeutic strategies targeting hormone receptors

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Apexbio Technology LLC Monomethyl auristatin E 474645-27-7 10mM (in 1mL DMSO)
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Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents

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Apexbio Technology LLC Monomethyl auristatin E 474645-27-7 1mg
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Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents

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Sigma Organic Chemistry Ethyl 7-bromoheptanoate | 5ml | 29823-18-5 | MFCD00037103
Ethyl 7-bromoheptanoate , 5ml
About this item:
CAS #: 29823-18-5
MDL #: MFCD00037103
Purity: ≥97
Molecular Weight: 237.13
UNSPSC Code: 12352100

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Sigma Organic Chemistry Fmoc N-hydroxysuccinimide ester | 25G | 82911-69-1 | MFCD00010733 | >=98.0% (HPLC)
Fmoc N-hydroxysuccinimide ester | 25G | 82911-69-1 | MFCD00010733 | >=98.0% (HPLC)

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Sigma Organic Chemistry (S)-alpha-Amino-gamma-butyrolactone hydrochloride | 1G | 104162 | MFCD00058172 | 0.97
(S)-alpha-Amino-gamma-butyrolactone hydrochloride | 1G | 104162 | MFCD00058172 | 0.97

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Sigma Aldrich Fine Chemicals Biosciences Methyl caprate United States Pharmacopeia (USP) Reference Standard | 110-42-9 | MFCD00009580 | 3X100MG
Methyl caprate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 186.29 | 110-42-9 | MFCD00009580 | 3X100MG

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Sigma Aldrich Fine Chemicals Biosciences Methyl 10-undecenoate 96% | 111-81-9 | MFCD00016689 | 25ML
Methyl 10-undecenoate 96% | Purity: 96% | Mol Wt: 198.3 | 111-81-9 | MFCD00016689 | 25ML

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Sigma Aldrich Fine Chemicals Biosciences Methyl linolenate >=99% (GC) | 301-00-8 | MFCD00135851 | 1G
Methyl linolenate >=99% (GC) | Purity: >=99% (GC) | Mol Wt: 292.46 | 301-00-8 | MFCD00135851 | 1G

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