Sphingolipids
Cayman Chemical C20 Ceramide d18 1 20 0
A natural 20:0 ceramide that is abundant in the brain; synthesized de novo by ceramide synthases 1 and 2
Cayman Chemical C20 Ceramide d18 1 20 0
A natural 20:0 ceramide that is abundant in the brain; synthesized de novo by ceramide synthases 1 and 2
Medchemexpress LLC Ceramide 3B | 178436-06-1 | 99.6% | 581.95 | 100 MG
Ceramide 3B is a ceramide 3 lipid class characterized by its aggregation behavior. It possesses various physiological functions, including acting as a penetration enhancer and an auxiliary emulsifier, contributing significantly to barrier function stability.
- Has aggregation behavior
- Can serve as a penetration enhancer
- Can serve as an auxiliary emulsifier
- Plays an important role in barrier function stability
Cayman Chemical C8 CeramIde-1-phosphated181mg
C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C8 ceramide-1-phosphate are essentially the opposite of C8 ceramide; it induces DNA synthesis and cell division. The effects of C8 ceramide-1-phosphate can be attenuated by simultaneous treatment with C2 or C8 ceramide.{5183}
Cayman Chemical C16 Ceramide d18 1 16 0
A sphingolipid; levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis; accumulates in the lungs of patients with cystic fibrosis compared with the lungs of patients with pulmonary hypertension; plasma levels are increased in patients with acute coronary syndrome, and an increased plasma ratio of C16 to C24:0 ceramide is associated with major adverse cardiac events; levels are increased in tumor tissue from patients with breast cancer and is associated with metastatic cancer
Medchemexpress LLC Sphingomyelin phosphodiesterase, Streptomyces sp. | 9031-54-3 | 10 U
Sphingomyelin phosphodiesterase, from Streptomyces sp., is a hydrolase involved in the sphingomyelin metabolism process. It catalyzes the conversion of sphingomyelin to phosphocholine and ceramide. This enzyme also plays a significant role in cellular differentiation, various immune and inflammatory responses, and intracellular cholesterol trafficking and metabolism.
- Hydrolase involved in sphingomyelin metabolism
- Catalyzes conversion of sphingomyelin to phosphocholine and ceramide
- Plays a significant role in cellular differentiation
- Important in various immune and inflammatory responses
- Involved in intracellular cholesterol trafficking and metabolism
- Intended for research use only
Apexbio Technology LLC Lyso-Tracker Red(Synonyms: LysoTracker Red DND-99, LysoTracker Red, LysoTracker Red fluorescent probe), 50ul, CAS: 231946-72-8.
Lyso-Tracker Red (CAS 231946-72-8) is a weakly basic fluorescent dye designed for labeling lysosomes in live cells. This cell-permeable molecule selectively accumulates within acidic lysosomal compartments due to protonation and subsequent entrapment in their low-pH environment. Unlike conventional lysosomal dyes such as neutral red and acridine orange, Lyso-Tracker Red displays superior organelle specificity, requiring nanomolar concentrations to clearly visualize lysosomes. Supplied as a 1 mM stock solution in DMSO, this probe is utilized for live-cell imaging studies investigating lysosomal function and trafficking pathways.
Apexbio Technology LLC Ceramide(Synonyms: N-Acylsphingosine, Ceramides, Acylsphingosine, sphingosine N-acyl derivative, N-Acyl-D-sphingosine), 5mg, CAS: 3102-57-6.
Ceramide (CAS 3102-57-6) is a bioactive lipid molecule known to modulate diverse cellular processes including proliferation and differentiation It exerts its effects primarily by activating several serine/threonine protein phosphatases notably protein phosphatase-1 (PP1) protein phosphatase-2A (PP2A) and ceramide-activated protein phosphatase (CAPP) in vitro Due to its regulatory role in fundamental signaling pathways ceramide serves as a valuable research tool in investigations addressing cell cycle progression apoptosis and cellular homeostasis
Cayman Chemical W-azIdo-C6 CeramIde 10mg
A clickable form of C6 ceramide; active against N. meningitidis and N. gonorrhoeae (MIC = 2 UG/ml for both); has been used to conjugate alkynylated fluorescent probes to liposomes containing ω-azido-C6 ceramide via a click reaction
Sigma Aldrich Fine Chemicals Biosciences Sphingomyelin chicken500MG
Sphingomyelin (SM) is a principal sphingolipid in mammalian cell membranes. Its biological functions have been studied.
Sigma Aldrich Fine Chemicals Biosciences Ceramide phosphorylethanol5MG
Ceramide phosphorylethanolamine is a phosphosphingolipid. It maintains the structural framework of the plasma membrane aids in the formation and functioning of plasma membrane lipid rafts cell signaling and transduction events. Ceramide phosphorylethanolamine modulates various cellular processes like growth differentiation apoptosis and angiogenesis.
Cayman Chemical C16 Sphingomyelin d18 1 16 0
A naturally occurring sphingolipid; levels are elevated in the prefrontal cortex and cerebellum in a rat model of STZ-induced diabetes, as well as in the liver in mouse models of Niemann-Pick type C1 disease; plasma are decreased in patients with prostate cancer; has been used in model membranes with POPC and cholesterol in the study of lipid raft dynamics and membrane organization