Sphingolipids
Medchemexpress LLC 3,5,9-trioxa-4-phosphaheptacosan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-, inner salt, 4-oxide | 74430-89-0 | MFCD00065889 | 99.7% | C26H56NO6P | 10MG
Lyso-PAF C-18 is a research-grade chemical intermediate used in the synthesis of C18-PAF, a ligand for the platelet-activating factor receptor. It is supplied as a white to off-white solid with high reported purity and is intended for laboratory research use only.
- High purity (99.7%).
- White to off-white solid form.
- Molecular formula C26H56NO6P.
- Molecular weight 509.70 g/mol.
- Powder stable at -20°C for up to 3 years.
- In-solution storage: -80°C for 6 months, -20°C for 1 month.
- Supplied in small research sizes suitable for synthesis and analytical work.
- For research use only; not for human or clinical use.
Cayman Chemical C20 Ceramide d18 1 20 0
A natural 20:0 ceramide that is abundant in the brain; synthesized de novo by ceramide synthases 1 and 2
Abcam N-Hexadecanoyl-D-erythro-C16-sphingosine, C16:0-Sphingosine ceramide analog.
N-Hexadecanoyl-D-erythro-C16-sphingosine, C16:0-Sphingosine ceramide analog.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC C16 ceramide-1-phosphate (d18:1/16:0) ammonium | 1246303-22-9 | 98.0% | 634.91 | C34H71N2O6P | 5 MG
C16 ceramide-1-phosphate (d18:1/16:0) (ammonium) is the ammonium salt of a bioactive sphingolipid, supplied as a purified research reagent for biochemical and cell biology studies of sphingolipid signaling and metabolism. It is provided as a characterized dry material for laboratory research use only and requires protected cold storage.
- High purity (98.0%).
- Molecular weight 634.91.
- Chemical formula C34H71N2O6P.
- Available in small pack sizes such as 5 MG.
- Storage: in solvent, -80°C (6 months) or -20°C (1 month); protect from light and store under nitrogen.
- Intended for biochemical assays and cell biology research; not for human use.
TARGETMOL CHEMICALS INC C22 Ceramide d18 1 22 0 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. C22 Ceramide (d181/220) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isolated rat liver mitochondria and liposomes. Purity 97.97%
Medchemexpress LLC N-acetyl-D-erythro-sphingosine | 3102-57-6 | MFCD00153903 | 99.9% | 341.53 g·mol⁻¹ | C20H39NO3 | 100 MG
C2 ceramide (N-acetyl-D-erythro-sphingosine, CAS 3102-57-6) is a short-chain ceramide used in cellular and biochemical research. It functions as a protein phosphatase activator and modulates signaling pathways involved in differentiation, autophagy, and apoptosis. Supplied as a solid suitable for dissolution in organic solvents.
- Activates protein phosphatases involved in cell regulation.
- Modulates differentiation, autophagy, and apoptosis.
- Inhibits mitochondrial respiratory complex III in some studies.
- Acts as a skin-conditioning agent that supports epidermal barrier function.
- High purity suitable for research applications.
Cayman Chemical C16 Ceramide d18 1 16 0
A sphingolipid; levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis; accumulates in the lungs of patients with cystic fibrosis compared with the lungs of patients with pulmonary hypertension; plasma levels are increased in patients with acute coronary syndrome, and an increased plasma ratio of C16 to C24:0 ceramide is associated with major adverse cardiac events; levels are increased in tumor tissue from patients with breast cancer and is associated with metastatic cancer
Cayman Chemical C8 CeramIde-1-phosphated185mg
C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C8 ceramide-1-phosphate are essentially the opposite of C8 ceramide; it induces DNA synthesis and cell division. The effects of C8 ceramide-1-phosphate can be attenuated by simultaneous treatment with C2 or C8 ceramide.{5183}
Cayman Chemical C12 NBD Ceramide d18 1 12 0
C12 NBD ceramide (d18:1/12:0) is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity.{14063} It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases from a variety of mammalian cell lines also hydrolyze C12 NBD ceramide (d18:1/12:0). Acid ceramidase does not appear to utilize C12 NBD ceramide (d18:1/12:0) as a substrate. The possibility exists forC12 NBD ceramide (d18:1/12:0) to also be applied to the measurement of ceramide kinase and/or sphingomyelin synthase activity.
Medchemexpress LLC C2 ceramide (N-acetylsphingosine) | 3102-57-6 | MFCD07374281 | 99.9% | 341.53 g/mol | C20H39NO3 | 25 MG
C2 ceramide (N-acetylsphingosine) is a short-chain ceramide research reagent used to modulate ceramide signaling and study cellular responses. It is used in biochemical and cell biology assays to probe protein phosphatase activity, mitochondrial function, and processes such as apoptosis, autophagy, and epidermal barrier behavior.
- Activates protein phosphatases PP1 and PP2A for signaling studies.
- Induces apoptosis and autophagy in cellular models.
- Affects mitochondrial respiratory chain for metabolic research.
- High-purity solid suitable for biochemical and cell-based assays.
- Stable when stored sealed at -20°C; follow solvent storage guidelines for solutions.
- Applicable to skin barrier and epidermal function research.
Cayman Chemical C16 Ceramide d18 1 16 0
A sphingolipid; levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis; accumulates in the lungs of patients with cystic fibrosis compared with the lungs of patients with pulmonary hypertension; plasma levels are increased in patients with acute coronary syndrome, and an increased plasma ratio of C16 to C24:0 ceramide is associated with major adverse cardiac events; levels are increased in tumor tissue from patients with breast cancer and is associated with metastatic cancer
Medchemexpress LLC C26 ceramide | 121459-09-4 | 99.9% | 678.17 g/mol | C44H87NO3 | 5 MG
C26-Ceramide is a long-chain ceramide lipid featuring two hydrophobic tails (one saturated, one unsaturated) supplied as a solid for biochemical research and formulation work. It is commonly used in developing lipid nanoparticles and liposomes, and for other lipid-focused studies.
- High purity for experimental consistency.
- Suitable for lipid nanoparticle and liposome formulation.
- Stable in powder form when stored under recommended conditions.
- Available in small milligram pack sizes for method development.
- Physical form: white to light brown solid.