Sphingolipids
Medchemexpress LLC C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) | 74713-59-0 | 98.0% | 425.69 | 1 G
C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. It exhibits anti-proliferation properties and functions as a potent chemotherapeutic agent. It stimulates dendritic cells to promote T cell responses during virus infections and induces slight activation of protein kinase (PKC) in vitro.
- Cell-permeable analog of ceramides
- Anti-proliferation and chemotherapeutic agent
- Stimulates dendritic cells for T cell responses
- Activates protein kinase C
- Reduces tumor-cell proliferation
- Induces necrosis-like cell death
- Increases ROS levels
- Triggers apoptosis and G1 arrest in NSCLC H1299 cells
- Enhances CD8+ and CD4+ T cell responses in viral infections
Medchemexpress LLC Lysophosphatidylcholine (15:0) | 108273-89-8 | MFCD00674356 | 99.6% | 481.60 | C23H48NO7P | 1 MG
15:0 Lyso PC is a lysophosphatidylcholine research reagent commonly used in lipidomics and biomarker investigations. It is formed by phospholipase A2 hydrolysis of phosphatidylcholine and is applied in studies of membrane remodeling, inflammatory signaling, and cardiovascular disease-related lipid disturbances.
- High purity: 99.6%.
- Well-defined molecular properties: C23H48NO7P, 481.60 g/mol.
- Supplied in small research pack sizes suitable for analytical work.
- Stable as powder when stored at -20°C for extended periods.
- Useful as a lipid biomarker in cardiovascular and metabolic studies.
- Compatible with lipidomics workflows and mass spectrometry analysis.
Medchemexpress LLC C16 ceramide-1-phosphate (d18:1/16:0) (ammonium) | 1246303-22-9 | 98% | C34H71N2O6P | 500 UG
C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium) is an ester product used as a laboratory chemical and for the manufacture of substances.
- Appears as a solid
- Stable under recommended storage conditions
- Store at -20°C, protect from light, and under nitrogen
- Suitable for laboratory use
Medchemexpress LLC C12-NBD Sphinganine | 474943-05-0 | 99.9% | C36H63N5O6 | 1 MG
C12-NBD Sphinganine is a fluorescent ceramidase substrate that can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources.
- Fluorescent ceramidase substrate
- Used for measuring alkaline and neutral ceramidase activity
- Molecular weight: 661.92
- Appearance: Solid
- Color: Light yellow to yellow
- Recommended storage at -20°C, sealed, away from moisture and light
- In solvent, stable for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC C26 ceramide | 121459-09-4 | 99.9% | 678.17 g/mol | C44H87NO3 | 10 MG
C26-Ceramide is a long-chain ceramide lipid (N-hexacosanoylsphingosine) composed of one saturated and one unsaturated hydrophobic tail. It is provided as a high-purity biochemical reagent for lipid research and formulation studies, including lipid nanoparticle and liposome development.
- High purity (99.89%) suitable for research applications.
- Long-chain ceramide structure with a C26 acyl chain.
- Useful for lipid nanoparticle and liposome formulation studies.
- Supplied in research-scale quantities for assay and formulation work.
- Molecular formula C44H87NO3; molecular weight 678.17 g/mol.
Medchemexpress LLC C26 ceramide | 121459-09-4 | 99.9% | 678.17 g/mol | C44H87NO3 | 5 MG
C26-Ceramide is a long-chain ceramide lipid featuring two hydrophobic tails (one saturated, one unsaturated) supplied as a solid for biochemical research and formulation work. It is commonly used in developing lipid nanoparticles and liposomes, and for other lipid-focused studies.
- High purity for experimental consistency.
- Suitable for lipid nanoparticle and liposome formulation.
- Stable in powder form when stored under recommended conditions.
- Available in small milligram pack sizes for method development.
- Physical form: white to light brown solid.
TARGETMOL CHEMICALS INC C16 CERAMIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. C16 Ceramide (Palmitoyl Ceramide) is a natural small molecule activating p53 through the direct and selective binding. purity: 99%
Medchemexpress LLC C6 Ceramide | 124753-97-5 | 99.8% | 397.63 | 25 MG
C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. It participates in the progression of multiple myeloma by suppressing the proliferation, migration, and angiogenesis of endothelial cells through targeting the Akt signal pathway. It also exhibits anti-cancer properties such as cell cycle arrest, apoptosis, inhibition of tumor growth, and enhances chemotherapy effects in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents to enhance anti-tumor effects.
- Enhances Trichostatin A (TSA)-induced cell death, apoptosis, and α-tubulin acetylation in CaOV3 and L3.6 cancer cells.
- Disrupts HDAC6/PP1/tubulin complex, leading to PP1 release and AKT dephosphorylation and inhibition.
- Increases miR29b expression and decreases Akt3, PI3K, and VEGFA expressions in HUVECs.
- Increases viable hippocampal neurons and enhances dendritic outgrowth in vitro.
Medchemexpress LLC C18:1-Ceramide | 5966-28-9 | 99.9% | C36H69NO3 | 50 MG
C18:1-Ceramide is a ceramide subspecies primarily used for research and analytical applications. It serves as an analytical standard and can be utilized in studies related to type 2 diabetes.
- Ceramide subspecies
- Intended for research and analytical applications
- Can be used in the study of type 2 diabetes
Medchemexpress LLC C26-ceramide | 121459-09-4 | MFCD18379264 | 99.9% | 678.17 g/mol | C44H87NO3 | 1 MG
C26-Ceramide is a very long-chain ceramide lipid consisting of a sphingoid base N-acylated with a C26 fatty acid. It is supplied as a high-purity biochemical reagent for lipid research and formulation work, including development of lipid nanoparticles and liposomes.
- Very long-chain ceramide with one saturated and one unsaturated hydrophobic tail.
- High purity (approximately 99.9%) suitable for analytical and formulation studies.
- Molecular weight 678.17 g/mol; chemical formula C44H87NO3.
- Supplied in small research quantities (example: 1 mg) for experimental use.
- Stable as a powder when stored at -20 °C; follow laboratory handling and storage guidelines.
Apexbio Technology LLC Lyso-Tracker Green(Synonyms: LysoTracker Green DND-26, LysoTracker Green, LysoTracker Green lysosomal probe), 50ul.
Lyso-Tracker Green is a fluorescent small-molecule probe designed specifically for labeling lysosomes in living cells. As a weakly basic fluorophore, it accumulates selectively in acidic cellular compartments, primarily lysosomes, due to protonation under low pH conditions. Unlike conventional dyes such as acridine orange or neutral red, Lyso-Tracker Green exhibits superior organellar selectivity and requires only nanomolar concentrations to produce robust fluorescent labeling. It is widely utilized in biomedical research for imaging lysosomal localization and analyzing cellular physiology in live-cell assays, but is not compatible with fixed-cell staining protocols.