Steroids and derivatives
Apexbio Technology LLC Estradiol 50-28-2 10mM (in 1mL DMSO)
Estradiol is an endogenous steroid hormone involved in the regulation of reproductive biology and cellular physiology through interaction with estrogen receptor (ER) subtypes and Estradiol binding to ER initiates genomic and non-genomic signaling pathways influencing transcription of diverse target genes related to proliferation differentiation and metabolism Estradiol-mediated ER signaling modulates cellular processes including epithelial-mesenchymal transition endothelial function oxidative stress responses and gene expression profiles in various cell lines such as HEK293 and U2OS Additionally estradiol treatment regulates cardiovascular function by inducing mitochondrial superoxide dismutase (SOD2) implicating protective effects in vascular conditions Estradiol exhibits ER subtype selectivity with reported ER and ER binding affinities (IC50) around 0 2-0 5 nM utilized broadly in estrogen signaling research and cardiovascular disease modelling
Sigma Aldrich Fine Chemicals Biosciences Hydrocortisone, 50-23-7, MFCD00011654, 1g
Empirical Formula (Hill Notation) C21H30O5, ≥98% (HPLC), Molecular Weight 362.46, mp 211-214 °C (lit.), Synonym: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M.
Medchemexpress LLC HY-113313 5mg Medchemexpress, Aldosterone CAS:52-39-1 Purity:>98%
Medchemexpress, HY-113313 5mg Aldosterone CAS:52-39-1 Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Br-PEG3-ethyl acetat 1g
Br-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Sigma Aldrich Fine Chemicals Biosciences Prednisone United States Pharmacopeia (USP) Reference Standard | 53-03-2 | MFCD00003608 | 250MG
Prednisone United States Pharmacopeia (USP) Reference Standard | Mol Wt: 358.43 | 53-03-2 | MFCD00003608 | 250MG
Sigma Aldrich Fine Chemicals Biosciences Reichstein's substance S >=98% | 152-58-9 | MFCD00003662 | 1G
Reichstein's substance S >=98% | Purity: >=98% | Mol Wt: 346.46 | 152-58-9 | MFCD00003662 | 1G
Sigma Aldrich Fine Chemicals Biosciences Ethisterone >=99% (HPLC) | 434-03-7 | MFCD00003656 | 25G
Ethisterone >=99% (HPLC) | Purity: >=99% (HPLC) | Mol Wt: 312.45 | 434-03-7 | MFCD00003656 | 25G
Sigma Aldrich Fine Chemicals Biosciences Cholic acid | 81-25-4 | MFCD00003672 | 60 mg
Cholic acid | Mol Wt: 408.57 | 81-25-4 | MFCD00003672 | 60 mg
Medchemexpress LLC Br-PEG3-ethyl acetat 250mg
Br-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Selleck Chemical LLC Cortisone
Cortisone is a pregnane steroid hormone and one of main substance released by the body as a reaction to stress It suppresses the immune system thus reducing inflammation and attendant pain and swelling at the site of the injury