Steroids and derivatives
Cambridge Isotope Laboratories 11-Dehydrocorticosterone (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
11-Dehydrocorticosterone (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
Cambridge Isotope Laboratories Permethrin (cis/trans mix) (unlabeled) 100 ug/mL in nonane 1 2 mL
Permethrin (cis/trans mix) (unlabeled) 100 ug/mL in nonane 1 2 mL
Cayman Chemical GlycocholIc ACD MaxSpec Sta
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Chem-Impex International, Inc. Glycocholic acid hydrate | 475-31-0 | MFCD06408004 | 5G
Glycocholic acid hydrate, 475-31-0, MFCD06408004, 5G
![Medchemexpress LLC Glycine, N-[(3α,5β, 7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1) | 863-57-0 | 487.60 | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000416267.png-250.jpg)
Medchemexpress LLC Glycine, N-[(3α,5β, 7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1) | 863-57-0 | 487.60 | 500 MG
Glycocholic acid sodium is an orally active bile acid that exhibits anticancer activity by targeting both pump resistance-related and non-pump resistance-related pathways.
- Orally active bile acid
- Possesses anticancer activity
- Targets pump resistance-related and non-pump resistance-related pathways
Cambridge Isotope Laboratories 6-Hydroxy-2 2 4 4 5-pentaBDE (unlabeled) 50 ug/mL in nonane 1 2 mL
6-Hydroxy-2 2 4 4 5-pentaBDE (unlabeled) 50 ug/mL in nonane 1 2 mL
Medchemexpress LLC Sodium glycocholate hydrate | 338950-81-5 | 99.9% | 1 G
Sodium glycocholate hydrate is a buffer commonly used in molecular biology and biochemical research. It provides precise pH control in various experimental settings and is intended for research use only.
- Buffer commonly used in molecular biology and biochemical research
- Provides precise pH control in various experimental settings
![Medchemexpress LLC Glycine, N-[(3α,5β, 7α, 12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt | 863-57-0 | 487.60 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000414849.png-250.jpg)
Medchemexpress LLC Glycine, N-[(3α,5β, 7α, 12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt | 863-57-0 | 487.60 | 1 ML
Glycine, N-[(3α,5β, 7α, 12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt | 863-57-0 | 487.60 | 1 ML
Medchemexpress LLC Glycocholic acid | 475-31-0 | 465.62 | 25 MG
Glycocholic acid is a bile acid with demonstrated anticancer activity. It targets both pump resistance-related and non-pump resistance-related pathways. It increases the cytotoxicity of epirubicin, enhances its intracellular accumulation, and improves its absorption, intensifying epirubicin-induced apoptosis. Combining it with anticancer drugs can help control multidrug resistance by modulating P-gp and MRPs, and by regulating apoptosis-related pathways.
- Increases cytotoxicity of epirubicin
- Enhances intracellular accumulation of epirubicin
- Improves absorption of epirubicin in rat small intestine
- Intensifies epirubicin-induced apoptosis
- Reduces mRNA expression of MDR1, MRP1, and MRP2
- Downregulates MDR1 promoter region
- Suppresses Bcl-2 mRNA expression
- Induces Bax mRNA expression
- Increases Bax-to-Bcl-2 ratio and mRNA levels of p53, caspase-9, and -3
Medchemexpress LLC Glycocholic acid | 475-31-0 | 465.62 | 1 ML
Glycocholic acid is a bile acid with anticancer activity, targeting both pump resistance-related and non-pump resistance-related pathways. It increases the cytotoxicity of epirubicin and significantly increases its intracellular accumulation and absorption.
- Intensifies epirubicin-induced apoptosis.
- Reduces mRNA expression levels of human intestinal MDR1, MDR-associated protein (MRP)1, and MRP2.
- Downregulates the MDR1 promoter region.
- Suppresses the mRNA expression of Bcl-2 and induces the mRNA expression of Bax.
- Increases the Bax-to-Bcl-2 ratio and the mRNA levels of p53, caspase-9, and -3.
- Can control multidrug resistance (MDR) by modulating P-gp and MRPs, and regulating apoptosis-related pathways when combined with anticancer drugs.
Medchemexpress LLC Glycocholic acid | 475-31-0 | 465.62 | 5 G
Glycocholic acid is a bile acid with anticancer activity, targeting pump resistance-related and non-pump resistance-related pathways. It is for research use only and not sold to patients.
- Appearance: Solid
- Color: White to off-white
- Classification: Steroids
- Initial source: Endogenous metabolite, human gut microbiota metabolites
- Increases the cytotoxicity of epirubicin
- Modulates P-gp and MRPs as well as regulating apoptosis-related pathways
Cayman Chemical GlycocholIc AcId-d4 5mg
An internal standard for the quantification of glycocholic acid by GC- or LC-MS
Medchemexpress LLC Glycocholic acid | 475-31-0 | 465.62 | 10 G
Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways. It works by modulating P-gp and MRPs, and regulating apoptosis-related pathways when combined with anticancer drugs.
- Increases cytotoxicity of epirubicin
- Increases intracellular accumulation and absorption of epirubicin
- Intensifies epirubicin-induced apoptosis
- Reduces mRNA expression levels of human intestinal MDR1, MDR-associated protein (MRP)1, and MRP2
- Downregulates the MDR1 promoter region
- Suppresses mRNA expression of Bcl-2
- Induces mRNA expression of Bax
- Increases Bax-to-Bcl-2 ratio and mRNA levels of p53, caspase-9 and -3
Medchemexpress LLC Glycocholic acid-d4 | 1201918-15-1 | 469.65 | 1 MG
Glycocholic acid-d4 is the deuterium-labeled Glycocholic acid. Glycocholic acid is a bile acid that exhibits anticancer activity by targeting pump resistance-related and non-pump resistance-related pathways.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.