Purine nucleotides
Selleck Chemical LLC Adenosine S1647-1g
Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a -N9-glycosidic bond
Medchemexpress LLC Adenosine 5'-triphosphate(ATP)-d4 ammonium salt | 2483831-82-7 | C10H24D4N9O13P3 | 1.16 MG
Adenosine 5'-triphosphate(ATP)-d4 (ammonium salt) is the deuterium labeled Adenosine 5'-triphosphate(ATP) ammonium salt. It is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC ATP-Red 1 (solution) | 1847485-97-5 | 561.48 | 56.14 UG
ATP-Red 1 is a multisite-binding switchable fluorescent probe designed for the selective and rapid detection of intracellular ATP concentrations in living cells. It features excitation at 510 nm and emission at 590 nm, making it suitable for various cell-staining applications.
- Selectively responds to intracellular ATP
- Rapid detection in living cells
- Excitation at 510 nm
- Emission at 590 nm
- Suitable for fluorescence microscopy or flow cytometry
Medchemexpress LLC Sonidegib diphosphate | 1218778-77-8 | 99.9% | 681.49 | 50 MG
Sonidegib diphosphate is a potent and selective Smoothened (Smo) antagonist that reduces the expression of downstream Hedgehog (Hh) signaling targets. It demonstrates dose-related antitumor activity in various preclinical models and is currently undergoing clinical trials for conditions such as Basal Cell Carcinoma and Hepatocellular Carcinoma.
- Potent and selective Smoothened (Smo) antagonist
- Reduces expression of downstream Hedgehog (Hh) signaling targets
- Inhibits Hh pathway in CD34+ chronic phase (CP)-chronic myeloid leukaemia (CML) cells
- Demonstrates dose-related antitumor activity in medulloblastoma models
- Undergoing clinical trials for various conditions
Medchemexpress LLC Adenosine, 1-oxide | 146-92-9 | MFCD00037993 | 99.5% | 283.24 g/mol | C10H13N5O5 | 25 MG
Adenosine N1-oxide is a nucleoside derivative used in research as an orally active anti-inflammatory agent. It has been reported to promote osteogenic and adipocyte differentiation and is supplied as a purified research-grade solid with supporting documentation (COA, SDS).
- CAS 146-92-9
- Molecular formula C10H13N5O5
- Molecular weight 283.24 g/mol
- Purity 99.50%
- Available in small vial sizes for research use (e.g., 1-25 mg)
- Documentation: certificate of analysis and safety data sheet available
Medchemexpress LLC Adenosine 5'-O-(2-thiodiphosphate) trilithium salt | 73536-95-5 | MFCD00077314 | 94.9% | C10H12Li3N5O9P2S | 10MG
ADP-β-S trilithium is the trilithium salt of adenosine 5'-β-thiodiphosphate, used in research as a P2Y12 receptor activator. It is supplied as a white to off-white solid (CAS 73536-95-5) with listed purity ~94.9% and molecular formula C10H12Li3N5O9P2S. Store sealed and away from moisture; in solution store at -80°C for long-term stability.
- Activator of P2Y12 receptor in cellular assays.
- Upregulates IL-1β and IL-6 production in microglial models.
- Promotes NF-κB phosphorylation and nuclear translocation.
- Enhances NLRP3 inflammasome activation in relevant studies.
- Provided as a solid suitable for preparation of assay solutions.
- Stable under recommended sealed, low-temperature storage conditions.
Sigma Aldrich Fine Chemicals Biosciences Adenosine-13C1015N5 5-mono1MG
REAGENT Adenosine-13C1015N5 5-mono1MG
Medchemexpress LLC Tenofovir diphosphate disodium | 2738719-07-6 | 99.4% | C9H14N5Na2O10P3 | 10MG
Tenofovir diphosphate disodium is the disodium salt of the active intracellular metabolite of tenofovir. It functions as an antiretroviral nucleotide analog and inhibitor of HIV-1 reverse transcriptase, and is provided for in vitro research into viral replication and polymerase activity. The compound is supplied as a solid for laboratory use.
- High purity (99.4%).
- Disodium salt form improves aqueous compatibility.
- Inhibits HIV-1 reverse transcriptase for biochemical assays.
- Available in small research pack sizes for laboratory experiments.
- Solid, white to off-white appearance for easy handling.
- Intended for research use only, not for human consumption.
Teknova 100mM ATP, pH 7.5. 100mL, Sterile (Dry Ice Intl Required) 10 pack.
100mM ATP, pH 7.5. 100mL, Sterile (Dry Ice Intl Required) 10 pack.
Medchemexpress LLC 6-O-methyl guanosine | 7803-88-5 | MFCD01723912 | 99.7% | 297.27 g·mol⁻1 | C11H15N5O5 | 5 MG
6-O-methyl guanosine is a modified nucleoside for biochemical research, reported to inhibit colony-forming ability in certain xeroderma pigmentosum cell lines. It is supplied as a solid reagent intended for in vitro studies and analytical applications.
- High purity (99.7%) suitable for analytical and biological experiments.
- Molecular weight 297.27 g·mol⁻1; formula C11H15N5O5.
- Soluble in DMSO (130 mg/mL); sparingly soluble in water (2 mg/mL); ultrasonic or warming recommended to aid dissolution.
- Stable as a powder at -20°C for extended storage.
- Available in small research quantities (for example, 5 mg) for laboratory use.