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Adenosine 5-triphosphate (ATP CAS 34369-07-8) also known as ATP disodium salt hydrate is a nucleotide central to cellular energy transfer It functions as the primary intracellular energy carrier undergoing hydrolysis to release energy required for numerous biochemical processes including muscle contraction signal transduction and biosynthetic reactions ATP also serves as a substrate for kinases in phosphorylation events and plays a regulatory role in purinergic signaling pathways In biomedical research ATP is widely used to study cellular metabolism enzyme activities and receptor-mediated responses
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Uridine diphosphate glucuronic acid is a nucleotide sugar that functions as the glucuronic acid donor in glucuronidation and polysaccharide biosynthesis. Supplied as a research-grade biochemical with documented purity and analytical documentation, it is used in enzymology, metabolic assays, and in vitro glycosylation studies.
Purity 98.0%.
Molecular weight 580.29 g·mol⁻¹; formula C15H22N2O18P2.
Used as a substrate or cofactor in glucuronyltransferase and enzymatic assays.
Suitable for in vitro metabolism and glycosylation studies.
Available in small research pack sizes including 25 mg.
Supplied with a certificate of analysis and safety data sheet.
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ADP-β-S trilithium is the trilithium salt of adenosine 5'-β-thiodiphosphate, used in research as a P2Y12 receptor activator. It is supplied as a white to off-white solid (CAS 73536-95-5) with listed purity ~94.9% and molecular formula C10H12Li3N5O9P2S. Store sealed and away from moisture; in solution store at -80°C for long-term stability.
Activator of P2Y12 receptor in cellular assays.
Upregulates IL-1β and IL-6 production in microglial models.
Promotes NF-κB phosphorylation and nuclear translocation.
Enhances NLRP3 inflammasome activation in relevant studies.
Provided as a solid suitable for preparation of assay solutions.
Stable under recommended sealed, low-temperature storage conditions.
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Adenosine antagonist-1 is a research-grade small molecule that acts as a selective adenosine A3 receptor (A3R) antagonist with reported anti-inflammatory activity. It is provided in solid and solution formats with analytical characterization suitable for in vitro pharmacology and receptor signaling studies.
Adenosine A3 receptor (A3R) antagonist.
Demonstrated anti-inflammatory activity.
High purity suitable for research applications (99.79%).
Molecular formula C18H13N7S and molecular weight 359.41 g/mol.
Available as solid and DMSO solution formats for flexible dosing.
Supplied for research use only; not for human use.
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LDE225 Diphosphate (CAS 1218778-77-8) is a highly potent and selective antagonist of the Smoothened (Smo) receptor a seven-transmembrane protein involved in the Hedgehog (Hh) signaling pathway LDE225 inhibits Smo with IC50 values of 1 3 nM for murine and 2 5 nM for human Smo resulting in suppression of Hh signaling This pathway is implicated in cellular differentiation proliferation and oncogenesis In vitro LDE225 selectively binds Smo inhibiting Hh-dependent tumor cell growth In vivo it demonstrates dose-dependent antitumor efficacy in medulloblastoma xenograft mouse models LDE225 continues to be explored as a research tool and therapeutic candidate in Hh pathway-driven malignancies
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