Purine nucleotides
Medchemexpress LLC ATP-polyamine-biotin | 1800401-93-7 | 98.06% | 50 MG
ATP-polyamine-biotin is the first cell-permeable ATP analogue, designed to function as an efficient kinase cosubstrate. It facilitates the biotin labeling of kinase substrates directly within live cells. This innovative compound allows for in vitro biotinylation experiments where the presence of the kinase, ATP-polyamine-biotin, and substrate leads to successful labeling, which is inhibited by kinase inhibitors or cleavage of the phosphoramidate bond.
- Promotes biotin labeling of kinase substrates in live cells.
- Functions as an efficient kinase cosubstrate.
- Observes biotinylation only in the presence of kinase.
- Inhibited by kinase inhibitors like staurosporine.
- Sensitive to acid incubation due to phosphoramidate bond cleavage.
Sigma Aldrich Fine Chemicals Biosciences Adenosine Deaminase from b
Molecular weight 32.5-33 kDapI 4.85
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 10MG
Adenosine receptor antagonist 2 is a small-molecule, orally active antagonist of A2a and A2b adenosine receptors with potent activity (IC50 1 nM at A2a, 3 nM at A2b) and reported anti-tumor effects. It is intended for research use in pharmacology and target-validation studies and is accompanied by supporting analytical documentation.
- Potent A2a and A2b receptor antagonism (IC50 1 nM and 3 nM).
- Orally active in preclinical models.
- Reported anti-tumor activity in studies.
- Supplied with analytical documentation, including datasheet, COA, and SDS.
- Suitable for in vitro and in vivo pharmacology and target validation.
Apexbio Technology LLC Adenosine Kinase Inhibitor (hydrate) 5mg
Adenosine Kinase Inhibitor (hydrate) is a small-molecule inhibitor targeting adenosine kinase It is designed to inhibit adenosine kinase thereby regulating intracellular adenosine metabolism Adenosine Kinase Inhibitor (hydrate) exerts its biological activity primarily through selective enzyme inhibition In cell-free conditions Adenosine Kinase Inhibitor (hydrate) demonstrates potent inhibitory activity with an IC50 value of approximately 1 7 nM Based on these pharmacological properties Adenosine Kinase Inhibitor (hydrate) holds research potential in investigating pain perception mechanisms and inflammation modulation through adenosine signaling pathways
Medchemexpress LLC Adenosine 5'-(tetrahydrogen triphosphate), sodium salt, hydrate (1:2:3) | 51963-61-2 | 99.91% | 1 ML
Adenosine 5'-(tetrahydrogen triphosphate), sodium salt, hydrate (1:2:3) | 51963-61-2 | 99.91% | 1 ML
Cambridge Isotope Laboratories Adenosine phosphoramidite (U-15N5 98%) CP 95% 10 mg
Adenosine phosphoramidite (U-15N5 98%) CP 95% 10 mg
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 25 MG
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. It exhibits anti-tumor activity and has been shown to inhibit tumor growth in vivo.
- Orally active A2a/A2b adenosine receptor antagonist
- Potent inhibition: IC50s of 1 nM (A2a) and 3 nM (A2b)
- Exhibits anti-tumor activity
- Inhibits tumor growth in female C57BL/6 mice
- Molecular weight: 444.46
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 25mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Medchemexpress LLC NHC-triphosphate tetraammonium | 97.09% | 567.28 | 1 MG
NHC-triphosphate tetraammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) in its triphosphate form. It acts as a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.
- May directly target the viral polymerase and act as a nonobligate chain terminator
- Plays a significant role in inhibiting early negative-strand RNA synthesis
- Interferes with correct replicase complex formation through chain termination or mutagenesis
Medchemexpress LLC Kinetin triphosphate tetrasodium | 99.9% | 675.2 g/mol | C15H16N5Na4O14P3 | 5 MG
Kinetin triphosphate tetrasodium is an ATP analogue provided as the tetrasodium salt for biochemical research. It modulates kinase activity and has documented use in studies such as Parkinson's disease research. Supplied as a small, concentrated vial suitable for in vitro kinase assays and mechanistic studies.
- High purity (99.92%).
- Supplied as the tetrasodium salt, water-soluble for aqueous assays.
- Provided in small vial sizes (5 mg; 100 mM when dissolved as indicated by supplier).
- Suitable for kinase activity assays and mechanistic studies.
- Datasheet, certificate of analysis, and safety data sheet available for quality and safety information.
Medchemexpress LLC Adenosine dialdehyde | 34240-05-6 | MFCD00056960 | 99.0% | 265.23 g/mol | C10H11N5O4 | 10MM 1ML
Adenosine dialdehyde is a purine nucleoside analogue that potently inhibits S-adenosylhomocysteine hydrolase (SAHH). It is used in biochemical assays and cancer research to study methylation-dependent pathways and can be supplied as a 10 mM solution in DMSO or as solid analytical standards.
![Medchemexpress LLC 2-amino-9-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one | 26578-09-6 | MFCD00064103 | 98.0% | 283.24 | C10H13N5O5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221802.png-250.jpg)
Medchemexpress LLC 2-amino-9-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one | 26578-09-6 | MFCD00064103 | 98.0% | 283.24 | C10H13N5O5 | 5 MG
L-Guanosine is the L-enantiomer of the purine nucleoside guanosine, provided as a research-grade small molecule for biochemical and antiviral studies and for preparing supramolecular hydrogels. The material is characterized with defined physicochemical properties and recommended storage and handling conditions.
- High purity: 98.0%.
- Molecular formula: C10H13N5O5; molecular weight: 283.24.
- Soluble in DMSO: approximately 100 mg/mL; ultrasonic assistance may be required.
- Storage recommendations: store at 4°C; in solution store at -80°C for long-term or -20°C short-term.
- Common applications: antiviral research, nucleoside chemistry, and hydrogel formation studies.
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 10mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Medchemexpress LLC Guanosine-15N5 | 99.6% | 288.21 | 1 MG
Guanosine-15N5 is an isotopically labeled form of Guanosine, where 15N (nitrogen-15) replaces the natural nitrogen atoms in the molecule. Guanosine is a purine nucleoside, formed by the attachment of guanine to a ribose sugar via a β-N9-glycosidic bond. This compound is primarily intended for research purposes.
- 15N labeled compound
- Purine nucleoside
- Formed from guanine and ribose
- Possesses anti-HSV activity
- Suitable for research applications