Purine nucleotides
Medchemexpress LLC 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl- | 26578-09-6 | 98.0% | 283.24 | 1 ML
L-Guanosine is the L-configuration of Guanosine, a purine nucleoside with anti-herpesvirus activity. It can be used to prepare supramolecular hydrogel and is intended for research use only.
- L-configuration of Guanosine
- Purine nucleoside
- Anti-herpesvirus activity
- Can be used to prepare supramolecular hydrogel
- Intended for research use only
Medchemexpress LLC 8-azidoadenosine 5'-triphosphate trisodium | 00-00-0 | 98.1% | 614.14 | C10H12N8Na3O13P3 | 5 MG
8-Azido-ATP trisodium is a photoreactive adenosine triphosphate analog supplied as the trisodium salt in solution. It is used to photo-crosslink and label ATP-binding proteins and serves as an azide-containing reagent for click chemistry and protein-nucleotide interaction studies.
- Photoreactive ATP analog for photo-crosslinking and protein identification.
- Azide functionality enables copper-catalyzed and strain-promoted click chemistry.
- Supplied as trisodium salt in a solution form suitable for direct use or dilution.
- High reported purity, supporting reproducible experimental results.
- Storage guidelines support frozen stock solutions for long-term stability.
Medchemexpress LLC ATP Citrate Lyase Antibody (YA596) | 121 kDa | 10 UL
ATP Citrate Lyase Antibody (YA596) is a rabbit host antibody reactive with human and mouse samples. It is supplied as a liquid at 1 mg/mL and is suitable for various applications including Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunoprecipitation, and Flow Cytometry.
- Rabbit host antibody
- Reacts with human and mouse samples
- Supplied as a liquid at 1 mg/mL
- Applications: Western Blot, ICC/IF, IHC-P, IP, FC
- Formulated in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol
- Contains 0.05% Sodium Azide preservative
- Stored at -20°C for 1 year
- Avoid repeated freeze / thaw cycles
Medchemexpress LLC Guanosine 5-Diphosphate 10Mmx1 | HY-113066A-10MMX1ML
Guanosine 5-Diphosphate 10Mmx1
Medchemexpress LLC Sonidegib diphosphate | 1218778-77-8 | 99.9% | 681.49 | 5 MG
Sonidegib diphosphate, also known as Erismodegib diphosphate, is a potent and selective Smoothened (Smo) antagonist. It works by directly interacting with Smo to reduce the expression of downstream Hedgehog (Hh) signaling targets. This compound has shown dose-related antitumor activity in medulloblastoma mouse models, effectively inhibiting tumor growth and causing regression at higher doses. It is for research use only.
- Potent and selective Smo antagonist
- Interacts directly with Smo to reduce expression of downstream Hh signaling targets
- Inhibits the Hh pathway in CD34+ chronic phase chronic myeloid leukemia (CML) cells
- Reduces the number and self-renewal capacity of CML leukemia stem cells (LSC)
- Demonstrates dose-related antitumor activity in medulloblastoma allograft mouse models
- Significantly inhibits tumor growth and affords regression at higher doses
Selleck Chemical LLC ATP S5260-1g
ATP (Adenosine-Triphosphate Adenosine 5 -triphosphate) is a multifunctional nucleoside triphosphate and an important endogenous signaling molecule in immunity and inflammation
Apexbio Technology LLC LDE225 Diphosphate 1218778-77-8 100mg
LDE225 Diphosphate (CAS 1218778-77-8) is a highly potent and selective antagonist of the Smoothened (Smo) receptor a seven-transmembrane protein involved in the Hedgehog (Hh) signaling pathway LDE225 inhibits Smo with IC50 values of 1 3 nM for murine and 2 5 nM for human Smo resulting in suppression of Hh signaling This pathway is implicated in cellular differentiation proliferation and oncogenesis In vitro LDE225 selectively binds Smo inhibiting Hh-dependent tumor cell growth In vivo it demonstrates dose-dependent antitumor efficacy in medulloblastoma xenograft mouse models LDE225 continues to be explored as a research tool and therapeutic candidate in Hh pathway-driven malignancies
Medchemexpress LLC Guanosine 5'-diphosphate disodium salt | 7415-69-2 | 98.2% | 487.16 | 100 MG
Guanosine 5'-diphosphate disodium salt | 7415-69-2 | 98.2% | 487.16 | 100 MG
Medchemexpress LLC L-adenosine | 3080-29-3 | MFCD01075784 | 99.8% | 267.25 g/mol | C10H13N5O4 | 1 ML
L-Adenosine is a metabolically stable enantiomeric analog used as a research probe with weak adenosine deaminase (ADA) inhibitory activity, suitable for studies of adenosine uptake and accumulation.
- 10 mM solution in DMSO, ready for use
- Pack size: 1 mL
- CAS number: 3080-29-3
- Purity: 99.82%
- Molecular weight: 267.25 g/mol
- Store stock solution at -80°C for long-term stability; protect from light
Medchemexpress LLC L-adenosine | 3080-29-3 | MFCD01075784 | 99.8% | 267.24 g/mol | C10H13N5O4 | 50 MG
L-adenosine is an enantiomeric analog of adenosine used as a research reagent and a weak adenosine deaminase (ADA) inhibitor (reported Ki = 385 μM). It is supplied as a high-purity solid for studies of adenosine uptake, accumulation, and ADA-related metabolism.
- High purity - 99.82% (reported).
- Suitable for adenosine uptake and accumulation studies.
- Weak ADA inhibitor (Ki ≈ 385 μM).
- Available as a 50 MG solid; additional pack sizes and DMSO solutions are offered.
- Molecular weight 267.24 g/mol; formula C10H13N5O4.
Medchemexpress LLC L-Adenosine | 3080-29-3 | MFCD01075784 | 99.8% | 267.25 | C10H13N5O4 | 10 MG
L-Adenosine is the L-enantiomer of adenosine, a metabolically stable nucleoside analog used as a research probe. It exhibits weak inhibitory activity against adenosine deaminase (ADA) and is used to study adenosine uptake and accumulation.
- CAS number 3080-29-3.
- Molecular formula C10H13N5O4; molecular weight 267.25.
- Purity 99.82% (typical).
- Physical form solid, white to off-white.
- Storage: 4°C, protect from light; in solvent -80°C for 6 months, -20°C for 1 month.
- Reported Ki for ADA: 385 μM.
Medchemexpress LLC L-adenosine | 3080-29-3 | MFCD01075784 | 99.8% | 267.25 g/mol | C10H13N5O4 | 5 MG
L-Adenosine is the L-enantiomer of adenosine used as a research reagent and probe. It exhibits weak adenosine deaminase (ADA) inhibitory activity and is supplied in high purity for biochemical and pharmacological studies.
- L-enantiomer of adenosine with defined stereochemistry.
- Weak adenosine deaminase (ADA) inhibitor suitable for enzyme assays.
- High reported purity (99.8%).
- Molecular formula C10H13N5O4 and molecular weight 267.25 g/mol.
- Available as solid and as pre-made 10 mM DMSO stock for convenient use.
Medchemexpress LLC ATP Citrate Lyase Antibody (YA596) | 121 kDa | 100 UL
The ATP Citrate Lyase Antibody (YA596) is a rabbit antibody designed for research use. It reacts with human and mouse samples and is supplied as a liquid at 1 mg/mL. This non-conjugated antibody is suitable for various applications including Western Blot, immunocytochemistry/immunofluorescence, immunohistochemistry-paraffin, immunoprecipitation, and flow cytometry.
- Host: Rabbit
- Reactivity: Human, mouse
- Clonality: YA596
- Concentration: 1 mg/mL
- Non-conjugated
- Applications: WB, ICC/IF, IHC-P, IP, FC
- Formulation: 1xTBS (pH 7.4), 0.05% BSA, 40% glycerol, 0.05% sodium azide
- Predicted molecular weight: 121 kDa
- Storage: -20°C for one year; avoid repeated freeze/thaw cycles
- Shipping: Blue ice
AdipoGen Guanosine 5-triphosphate Na
Chemical. CAS 36051-31-7. Formula C10H16N5O14P3 . xNa. Molecular Weight 523.18 free acid basis. Guanosine 5-triphosphate GTP trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. It also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. GTP is involved in the initiation of peptide synthesis during the binding of formylmethionyl-tRNA F-met-tRNA to the ribosome. It is also involved in polypeptide chain elongation.