Purine nucleotides
Medchemexpress LLC Adenosine 5'-O-(2-thiodiphosphate) trilithium salt | 73536-95-5 | MFCD00077314 | 94.9% | C10H12Li3N5O9P2S | 10MG
ADP-β-S trilithium is the trilithium salt of adenosine 5'-β-thiodiphosphate, used in research as a P2Y12 receptor activator. It is supplied as a white to off-white solid (CAS 73536-95-5) with listed purity ~94.9% and molecular formula C10H12Li3N5O9P2S. Store sealed and away from moisture; in solution store at -80°C for long-term stability.
- Activator of P2Y12 receptor in cellular assays.
- Upregulates IL-1β and IL-6 production in microglial models.
- Promotes NF-κB phosphorylation and nuclear translocation.
- Enhances NLRP3 inflammasome activation in relevant studies.
- Provided as a solid suitable for preparation of assay solutions.
- Stable under recommended sealed, low-temperature storage conditions.
Medchemexpress LLC Uridine 5'-(trihydrogen diphosphate), 4-oxime | 39023-73-9 | 98.8% | 419.18 | 10 MG
NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) in a diphosphate form. NHC is a pyrimidine ribonucleoside and acts as a potent anti-virus agent, effectively inhibiting the replication of Venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV), and hepatitis C virus (HCV).
- Active phosphorylated intracellular metabolite
- Potent anti-virus agent
- Inhibits replication of Venezuelan equine encephalitis virus (VEEV)
- Inhibits replication of Chikungunya virus (CHIKV)
- Inhibits replication of hepatitis C virus (HCV)
- For research use only
- Soluble in H2O: 160 mg/mL (needs ultrasonic)
- Store at -20°C, protect from light, stored under nitrogen
Sigma Aldrich Fine Chemicals Biosciences Chloroquine diphosphate sa250G
Chloroquine is a member of quinolone family and is a weak intercalating agent. Chloroquine is used for treating amebiasis rheumatoid arthritis discoid and systemic lupus erythematosus.
Medchemexpress LLC Uridine diphosphate glucuronic acid | 2616-64-0 | 98.0% | 580.29 g·mol⁻¹ | C15H22N2O18P2 | 25MG
Uridine diphosphate glucuronic acid is a nucleotide sugar that functions as the glucuronic acid donor in glucuronidation and polysaccharide biosynthesis. Supplied as a research-grade biochemical with documented purity and analytical documentation, it is used in enzymology, metabolic assays, and in vitro glycosylation studies.
- Purity 98.0%.
- Molecular weight 580.29 g·mol⁻¹; formula C15H22N2O18P2.
- Used as a substrate or cofactor in glucuronyltransferase and enzymatic assays.
- Suitable for in vitro metabolism and glycosylation studies.
- Available in small research pack sizes including 25 mg.
- Supplied with a certificate of analysis and safety data sheet.
Medchemexpress LLC Inosine 5′-diphosphate sodium | 81012-88-6 | 98.2% | 512.15 | 100 MG
Inosine 5′-diphosphate sodium is a purine ribonucleoside 5′-diphosphate with inosine as the nucleobase. It participates in intracellular energy metabolism and signal transduction processes.
- Purine ribonucleoside 5′-diphosphate
- Solid appearance, white to off-white in color
- Soluble in water (≥ 116.67 mg/mL)
- For research use only
Medchemexpress LLC Inosine 5'-diphosphate sodium | 81012-88-6 | 98.17% | 512.15 | 25 MG
Inosine 5′-diphosphate sodium is a purine ribonucleoside 5′-diphosphate with inosine as the nucleobase. It can participate in intracellular energy metabolism and signal transduction processes. This product is for research use only.
- Purine ribonucleoside
- Involved in intracellular energy metabolism
- Participates in signal transduction processes
- Useful for research in respiratory and metabolic diseases
- Classified as a nucleotide analog and endogenous metabolite
Medchemexpress LLC Uridine diphosphate glucuronic acid | 2616-64-0 | 98.0% | 580.29 g/mol | C15H22N2O18P2 | 10MG
Uridine diphosphate glucuronic acid (UDP-GlcA) is a sugar nucleotide cofactor used in biochemical and enzymatic research. It participates in glucuronidation and nucleotide sugar metabolism and serves as a substrate for glycosyltransferases and UDP-glucose dehydrogenase assays. The reagent is supplied for research use in biochemical assays and pathway studies.
- High purity (98.0%) for reliable assay performance.
- Molecular weight 580.29 g/mol and formula C15H22N2O18P2 for precise calculations.
- Available in small pack sizes including 10 mg for screening and method development.
- Suitable as a substrate in enzymatic and glycosylation studies.
- Provided with batch-specific COA and SDS for traceability.
Research Products International Corp Coenzyme A Trilithium Salt, 25 MG
Coenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes.
Medchemexpress LLC Sonidegib diphosphate | 1218778-77-8 | 99.9% | 681.49 | 50 MG
Sonidegib diphosphate is a potent and selective Smoothened (Smo) antagonist that reduces the expression of downstream Hedgehog (Hh) signaling targets. It demonstrates dose-related antitumor activity in various preclinical models and is currently undergoing clinical trials for conditions such as Basal Cell Carcinoma and Hepatocellular Carcinoma.
- Potent and selective Smoothened (Smo) antagonist
- Reduces expression of downstream Hedgehog (Hh) signaling targets
- Inhibits Hh pathway in CD34+ chronic phase (CP)-chronic myeloid leukaemia (CML) cells
- Demonstrates dose-related antitumor activity in medulloblastoma models
- Undergoing clinical trials for various conditions
TARGETMOL CHEMICALS INC Guanosine 5-diphosphate disodi
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. Purity 98%
Apexbio Technology LLC Primaquine Diphosphate 63-45-6 10g
Primaquine Diphosphate is an 8-aminoquinoline derivative utilized primarily as an antimalarial agent targeting the extraerythrocytic liver stage of malaria parasites While its precise IC50 values remain unspecified primaquine s biological activity involves interference with nucleic acid function subsequently disrupting protein synthesis pathways and lipid biosynthesis and inducing membrane disturbances In vitro primaquine has been applied in cell culture models to investigate antiviral effects demonstrating dose-dependent inhibition of Newcastle disease virus replication and modulation of viral RNA synthesis In vivo experiments using radiolabeled primaquine-loaded liposomes in murine models illustrate pronounced hepatic accumulation Clinically this compound is employed as prophylaxis against malaria infections (e g Plasmodium falciparum and P vivax)
Apexbio Technology LLC Primaquine Diphosphate 63-45-6 10mM (in 1mL DMSO)
Primaquine Diphosphate is an 8-aminoquinoline derivative utilized primarily as an antimalarial agent targeting the extraerythrocytic liver stage of malaria parasites While its precise IC50 values remain unspecified primaquine s biological activity involves interference with nucleic acid function subsequently disrupting protein synthesis pathways and lipid biosynthesis and inducing membrane disturbances In vitro primaquine has been applied in cell culture models to investigate antiviral effects demonstrating dose-dependent inhibition of Newcastle disease virus replication and modulation of viral RNA synthesis In vivo experiments using radiolabeled primaquine-loaded liposomes in murine models illustrate pronounced hepatic accumulation Clinically this compound is employed as prophylaxis against malaria infections (e g Plasmodium falciparum and P vivax)
Medchemexpress LLC Tenofovir diphosphate disodium | 2738719-07-6 | 99.4% | C9H14N5Na2O10P3 | 10MG
Tenofovir diphosphate disodium is the disodium salt of the active intracellular metabolite of tenofovir. It functions as an antiretroviral nucleotide analog and inhibitor of HIV-1 reverse transcriptase, and is provided for in vitro research into viral replication and polymerase activity. The compound is supplied as a solid for laboratory use.
- High purity (99.4%).
- Disodium salt form improves aqueous compatibility.
- Inhibits HIV-1 reverse transcriptase for biochemical assays.
- Available in small research pack sizes for laboratory experiments.
- Solid, white to off-white appearance for easy handling.
- Intended for research use only, not for human consumption.
Medchemexpress LLC Uridine diphosphate glucuronic acid | 2616-64-0 | 98.0% | 580.29 g/mol | C15H22N2O18P2 | 1MG
Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a nucleotide sugar cofactor used as the glucuronic acid donor in enzymatic glucuronidation and polysaccharide biosynthesis studies. Supplied as a high-purity research reagent, the product is provided in milligram pack sizes and includes supporting documentation for quality and safe handling.
- High purity (98.0%) suitable for biochemical assays.
- Provided with certificate of analysis and safety data sheet for verification.
- Available in multiple milligram pack sizes to support small-scale experiments.
- Used as a glucuronic acid donor in enzymatic and metabolic studies.
- Stable when stored and handled according to provided instructions.