Pyridine nucleotides
Medchemexpress LLC Nicotinamide N-Methy 50ug | 50ug
The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator affecting adipose tissue energy expenditure gluconeogenesis and cholesterol biosynthesis Nicotinamide N-Methyltransferase/NNMT Protein Human (His) is the recombinant human-derived Nicotinamide N-Methyltransferase/NNMT protein expressed by E coli with C-His labeled tag
Medchemexpress LLC Nicotinamide N-Methy 100ug | 100ug
The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator affecting adipose tissue energy expenditure gluconeogenesis and cholesterol biosynthesis Nicotinamide N-Methyltransferase/NNMT Protein Human (His) is the recombinant human-derived Nicotinamide N-Methyltransferase/NNMT protein expressed by E coli with C-His labeled tag
Medchemexpress LLC Aica-riboside, 5'-phosphate | 3031-94-5 | MFCD00057264 | 100.0% | C9H15N4O8P | 10MG
AICA-riboside, 5′-phosphate is the 5′-phosphorylated form of AICA-riboside that functions as an AMP mimetic and activator of AMP-activated protein kinase (AMPK). It is provided as a high-purity solid for biochemical and cellular research into metabolic and neurological pathways.
- Acts as an AMP mimetic and activates AMP-activated protein kinase.
- Provided as a high-purity solid suitable for biochemical studies.
- Molecular formula C9H15N4O8P and molecular weight 338.21 g·mol⁻¹.
- Available in small quantities for experimental use.
- Commonly used in metabolic disease and neuroprotection research.
Medchemexpress LLC AICA-riboside, 5′-phosphate | 3031-94-5 | 100.0% | 338.21 g·mol⁻¹ | C9H15N4O8P | 5 MG
AICA-riboside, 5′-phosphate is the 5′-phosphorylated form of AICA-riboside that acts as an AMP mimetic and modulates adenosine uptake. It is used as a research reagent to activate AMP-activated protein kinase (AMPK) and to investigate cellular energy metabolism, metabolic disease models, and neuroprotective mechanisms.
- Activates AMP-activated protein kinase via AMP mimetic activity.
- Modulates adenosine uptake and extracellular adenosine concentration.
- Used in studies of metabolic and neurological disorders.
- Provided as a solid with manufacturer-stated high purity.
- Available in small pack sizes suitable for laboratory research.
Medchemexpress LLC Nicotinamide 1,N6-ethenoadenine dinucleotide | 38806-38-1 | ≥99.0% | 687.45 | 1 MG
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) is a fluorescent analog of NAD. This compound is known for its ability to be cleaved by phosphodiesterase I and to bind to bovine liver glutamate dehydrogenase. It functions as a substrate for G-ADP ribosylation of G proteins, a reaction facilitated by bacterial toxins, and is widely used as a fluorescent substrate for the study of ADP ribosylation reactions.
- Fluorescent analog of NAD
- Cleaved by phosphodiesterase I (from C. adamanteus venom)
- Binds to bovine liver glutamate dehydrogenase
- Serves as a substrate for G-ADP ribosylation of G proteins
- Used as a fluorescent substrate for studying ADP ribosylation reactions
Medchemexpress LLC Oxidized low density lipoprotein (mouse) | ≥98% | 1 MG
Oxidized low density lipoprotein (mouse) (Mouse ox-LDL) is an oxidized low density lipoprotein (LDL). It induces atherosclerosis (AS) by facilitating endothelial dysfunction and accelerating the VSMCs growth and migration, making it suitable for constructing an in vitro model of AS.
- Induces atherosclerosis (AS)
- Facilitates endothelial dysfunction
- Accelerates VSMCs growth and migration
- Can be used to construct an in vitro model of AS
- Upregulates mRNA and protein expressions of long noncoding RNA TUG1 and receptor tyrosine kinase-like orphan receptor 2 (ROR2)
- Promotes the proliferation of HA-VSMCs
- Enhances migration and invasion abilities
- Increases the expressions of metastasis-related proteins β-catenin and Vimentin in human aortic vascular smooth muscle cells
Medchemexpress LLC Pyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, chloride (1:1) | 23111-00-4 | MFCD27952781 | 99.6% | 290.70 g/mol | C11H15ClN2O5 | 100G
Nicotinamide riboside chloride is the chloride salt of nicotinamide riboside, a vitamin B3-derived NAD+ precursor provided as a research-grade white to off-white powder for biochemical and metabolic studies. It is used to elevate cellular NAD+ levels and to investigate sirtuin activation, energy metabolism, and aging-related pathways.
- Increases cellular NAD+ levels.
- Activates sirtuin proteins SIRT1 and SIRT3.
- Chloride salt form with good aqueous solubility.
- Suitable for in vitro and in vivo metabolic research.
- High-purity, batch-verified material for reproducible results.