Pyrimidine nucleosides
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 100.0% | 10 MM 1 ML
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. It serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. Additionally, 2'-deoxyuridine reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Reduces microglial activation.
- Improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury.
- Promising for Alzheimer's disease (AD) research.
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.95% | 1 ML
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of Bromodeoxyuridine (Brdu)
- Essential for nucleic acid synthesis
- Can be used for cancer research
- Intended for research use only
Medchemexpress LLC 2'-Deoxycytidine (Standard) | 951-77-9 | MFCD00006547 | 99.95% | 50 MG
2'-Deoxycytidine (Standard) is an analytical standard used as a reference for assays. It is commonly employed in various research experiments, including qualitative, quantitative, and methodological studies.
- Serves as a reference standard for assays.
- Utilized in qualitative research experiments.
- Utilized in quantitative research experiments.
- Utilized in methodological research experiments.
- Applicable in HPLC (High-Performance Liquid Chromatography).
- Applicable in GC (Gas Chromatography).
- Applicable in MS (Mass Spectrometry).
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 98.0% | 500 MG
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of bromodeoxyuridine (Brdu).
- Essential for nucleic acid synthesis.
- Used in cancer research.
- Target: endogenous metabolite.
Medchemexpress LLC 2'-deoxyuridine-1′-13C | 478510-85-9 | 99.5% | 10 MG
2'-Deoxyuridine-1′-13C is a 13C-labeled isotopologue of 2'-deoxyuridine supplied as a research reagent and analytical standard for metabolite and isotope-labeling studies. It is provided as a powder with high chemical purity and defined storage recommendations.
Medchemexpress LLC Uridine, 2'-deoxy-4-thio- | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g·mol⁻¹ | C9H12N2O4S | 5 MG
4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analog supplied as a light-yellow solid and used as a research reagent in studies of DNA synthesis, nucleoside metabolism, and antitumor mechanisms. It is characterized for biochemical and cell-based experiments and provided with supporting analytical data.
- High purity (99.8%) for research applications.
- Sulfur-substituted nucleoside for incorporation and metabolism studies.
- Stable solid form with recommended low-temperature storage.
- Well-characterized molecular properties (C9H12N2O4S; 244.27 g·mol⁻¹).
- Available in small quantities suitable for laboratory-scale experiments.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 500 MG
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has shown promise in Alzheimer's disease (AD) research by reducing microglial activation and improving oxidative stress damage through modulation of glycolytic metabolism on Aβ25-35-induced brain injury.
- Associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Precursor in the synthesis of edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
Medchemexpress LLC 2'-deoxycytidine-2'-13C | >98.0% | 228.21 g/mol | C8 13CH13N3O4 | 1 MG
13C-labeled 2'-deoxycytidine supplied as a research-grade stable isotope standard for analytical and tracer studies. Supplied in a small 1 mg pack with reported high purity, it is intended for use in metabolite tracing, mass spectrometry calibration, and other analytical applications.
- Stable isotope labeled (13C) standard for analytical methods.
- Suitable for metabolite tracing and mass spectrometry quantitation.
- High reported purity (>98.0%).
- Supplied in a small research pack suitable for analytical use.
- Provided as a solid, easy to store and handle in laboratory settings.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 50 MG
2'-deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide
- Associated with nervous system diseases
- Increases chromosome breakage
- Decreases thymidylate synthetase activity
- Reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury
- Promising for Alzheimer's disease (AD) research
- Appearance: Solid
- Color: White to off-white
Apexbio Technology LLC 5-Ethynyl-2'-deoxyuridine (5-EdU), 1g CAS# 61135-33-9
5-Ethynyl-2'-deoxyuridine (5-EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation. 5-EdU can be used as a replacement for BrdU (5-Bromo-2'-deoxyuridine) to measure de novo DNA synthesis during the S-phase of the cell cycle through click chemistry. Click chemistry is a method of covalently coupling an azide with an alkyne. 5-EdU has an alkyne handle that can be detected using azide-containing fluorescent probes through a highly efficient click chemistry reaction. In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. 5-EdU-labelled cells may be isolated to determine the transcript of cells, from neural cancer or tissues that have undergone division in vitro and in vivo. Other sizes are also available. Please inqury us for quote.