Pyrimidine nucleosides
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 500 MG
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has shown promise in Alzheimer's disease (AD) research by reducing microglial activation and improving oxidative stress damage through modulation of glycolytic metabolism on Aβ25-35-induced brain injury.
- Associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Precursor in the synthesis of edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
Medchemexpress LLC 2'-Deoxyuridine-1'-13C | 478510-85-9 | 5 MG
2'-Deoxyuridine-1'-13C is a carbon-13 labeled version of 2'-Deoxyuridine. This compound induces chromosome breakage, thereby reducing the synthesis activity of thymidylate. Additionally, it serves as a precursor in the synthesis of Edoxudine.
- Carbon-13 labeled version of 2'-Deoxyuridine.
- Induces chromosome breakage.
- Reduces synthesis activity of thymidylate.
- Serves as a precursor in the synthesis of Edoxudine.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 1 G
2'-Deoxyuridine is a brain-penetrant pyrimidine nucleotide associated with nervous system diseases. It can increase chromosome breakage and reduce thymidylate synthetase activity. This compound serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has demonstrated the ability to lessen microglial activation and enhance oxidative stress damage by modulating glycolytic metabolism in brain injury models, indicating its potential for Alzheimer's disease research.
- Brain-penetrant pyrimidine nucleotide.
- Associated with nervous system diseases.
- Can increase chromosome breakage.
- Reduces thymidylate synthetase activity.
- Precursor in synthesis.
- Analogue of other compounds.
- Reduces microglial activation.
- Improves oxidative stress damage.
- Modulates glycolytic metabolism in brain injury.
- Promising for Alzheimer's disease research.
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.95% | 1 ML
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of Bromodeoxyuridine (Brdu)
- Essential for nucleic acid synthesis
- Can be used for cancer research
- Intended for research use only
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
Medchemexpress LLC 2-Deoxycytidine | 951-77-9 | MFCD23103479 | 99.95% | 25 MG
2-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for the research of cancer.
- Essential for nucleic acid synthesis.
- Used in cancer research.
- Deoxyribonucleoside.
- Can inhibit biological effects of Bromodeoxyuridine (Brdu).
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 50 MG
2'-deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide
- Associated with nervous system diseases
- Increases chromosome breakage
- Decreases thymidylate synthetase activity
- Reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury
- Promising for Alzheimer's disease (AD) research
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 98.0% | 500 MG
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of bromodeoxyuridine (Brdu).
- Essential for nucleic acid synthesis.
- Used in cancer research.
- Target: endogenous metabolite.
Medchemexpress LLC 2'-Deoxyuridine-1'-13C | 478510-85-9 | 1MG
2'-Deoxyuridine-1'-13C is a stable isotope-labeled compound with the molecular formula C813CH12N2O5 and a molecular weight of 229.19. It appears as a white to off-white solid with an isotopic enrichment of 99%. This product is intended for research use only and has not been fully validated for medical applications.
- White to off-white solid appearance
- Isotopic enrichment of 99%
- Molecular formula C813CH12N2O5
- Intended for research use only
- Store powder at -20°C for up to 3 years or at 4°C for up to 2 years
- Store in solvent at -80°C for 6 months or at -20°C for 1 month
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 100.0% | 5 G
2'-Deoxycytidine, a deoxyribonucleoside, can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Deoxyribonucleoside
- Inhibits biological effects of bromodeoxyuridine (Brdu)
- Essential for the synthesis of nucleic acids
- Can be used for cancer research
- Inhibits tumor growth in mice
Medchemexpress LLC 2'-Deoxycytidine (Standard) | 951-77-9 | MFCD00006547 | 99.95% | 50 MG
2'-Deoxycytidine (Standard) is an analytical standard used as a reference for assays. It is commonly employed in various research experiments, including qualitative, quantitative, and methodological studies.
- Serves as a reference standard for assays.
- Utilized in qualitative research experiments.
- Utilized in quantitative research experiments.
- Utilized in methodological research experiments.
- Applicable in HPLC (High-Performance Liquid Chromatography).
- Applicable in GC (Gas Chromatography).
- Applicable in MS (Mass Spectrometry).
Apexbio Technology LLC 5-Ethynyl-2'-deoxyuridine (5-EdU), 1g CAS# 61135-33-9
5-Ethynyl-2'-deoxyuridine (5-EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation. 5-EdU can be used as a replacement for BrdU (5-Bromo-2'-deoxyuridine) to measure de novo DNA synthesis during the S-phase of the cell cycle through click chemistry. Click chemistry is a method of covalently coupling an azide with an alkyne. 5-EdU has an alkyne handle that can be detected using azide-containing fluorescent probes through a highly efficient click chemistry reaction. In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. 5-EdU-labelled cells may be isolated to determine the transcript of cells, from neural cancer or tissues that have undergone division in vitro and in vivo. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.95% | 1 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of Brdu.
- Essential for nucleic acid synthesis.
- Used in cancer research.
- Inhibits tumor growth in vivo.