Pyrimidine nucleotides
Medchemexpress LLC D-Glucosamine 6-phosphate | 3616-42-0 | MFCD00067382 | 259.15 | 25 MG
D-Glucosamine 6-phosphate is an endogenous metabolite that can be synthesized by glutamine fructose-6-phosphate amidotransferase (GFAT). It can be used for the research of diabetes mellitus.
- Endogenous metabolite
- For research use only (not for sale to patients)
Medchemexpress LLC Uridine-5'-diphosphoglucose pyrophosphorylase | 9026-22-6 | 25 U
Uridine-5'-diphosphoglucose pyrophosphorylase is involved in the catalysis of UDP-glucose synthesis and can be utilized to determine the concentration of pyrophosphate in urine.
- Involved in the catalysis of UDP-glucose synthesis.
- Can be used to determine the concentration of pyrophosphate in urine.
Medchemexpress LLC UDP-xylose (disodium) | 108320-89-4 | 580.24 | 50 MG
UDP-xylose (disodium) | 108320-89-4 | 580.24 | 50 MG
Medchemexpress LLC Uridine (β-Uridine) | 58-96-8 | 99.97% | 500 MG
Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, connected by a β-N1-glycosidic bond. It is categorized as a human endogenous metabolite. It offers various biological activities including antiproliferative, anti-fibrotic, and cardioprotective effects.
- Inhibits proliferation of leukemia cells and induces differentiation
- Alleviates CCl4-induced liver fibrosis by suppressing pro-inflammatory cytokines
- Exhibits anti-ischemic, antioxidant, and anti-arrhythmic effects in rat models
- Soluble in H2O and DMSO for in vitro applications
- Can be prepared in various in vivo dissolution protocols for diverse research needs
Medchemexpress LLC UDP-GlcNAz disodium | 1611490-64-2 | 99.7% | C17H24N6Na2O17P2 | 25 MG
UDP-GlcNAz disodium is an analogue of UDP-GlcNAc disodium. It is a click chemistry reagent, capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. It also acts as a sugar donor and a substrate for OGTase and O-GlcNAcase, valuable in protein glycosylation research.
- Analogue of UDP-GlcNAc disodium
- Functions as a click chemistry reagent
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Acts as a sugar donor
- Serves as a substrate for OGTase and O-GlcNAcase
- Can glycosylate p62
- Glycosidic bond can be cleaved by O-GlcNAcase through catalysis
- Incorporated into nuclear proteins in Jurkat cells in *in vitro* studies
Medchemexpress LLC Uridine 5'-diphosphoglucose (standard) | 133-89-1 | 99.6% | 566.30 | 10 MG
Uridine 5'-diphosphoglucose (standard) | 133-89-1 | 99.6% | 566.30 | 10 MG
Medchemexpress LLC UDP-GlcNAc disodium | 91183-98-1 | 99.9% | 651.32 | 100 MG
UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT). OGT is a nucleocytoplasmic glycosyltransferase that modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates, mainly confined within the cytosol and nucleus.
- Donor substrate of O-GlcNAc transferase (OGT).
- For research use only.
Medchemexpress LLC Uridine | 58-96-8 | 100.0% | 10 MM * 1 ML
Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, connected by a β-N1-glycosidic bond. This product is for research use only.
- Inhibits proliferation of certain leukemia cells
- Induces cell differentiation
- Alleviates liver fibrosis
- Inhibits pro-inflammatory cytokines
- Activates the NF-κB signaling pathway
- Provides anti-ischemic, antioxidant, and anti-arrhythmic effects
- Protects against acute myocardial ischemia and reperfusion injury
Medchemexpress LLC D-Glucosamine 6-phosphate (Standard) | 3616-42-0 | 259.15 | 1MG
D-Glucosamine 6-phosphate (Standard) is a laboratory chemical used in the manufacture of substances. It is stable under recommended storage conditions, which include -20°C in a sealed, dry environment, away from light and moisture. In solvent, it can be stored at -80°C for 6 months or -20°C for 1 month. Short-term shipping at room temperature (less than 2 weeks) is acceptable.
- Classified as a laboratory chemical
- Used for the manufacture of substances
- Stable under recommended storage conditions
- Long-term storage at -20°C in a sealed, dry environment, away from light and moisture
- Can be stored in solvent at -80°C for 6 months or -20°C for 1 month
- Can be shipped at room temperature for durations less than 2 weeks
Medchemexpress LLC Glucosamine (hydrochloride) | 66-84-2 | 215.63 | 1 G
Glucosamine hydrochloride is an amino sugar and a precursor in the biochemical synthesis of glycosylated proteins and lipids. It is used as a dietary supplement and is a natural constituent of glycosaminoglycans in cartilage matrix and synovial fluid. When administered exogenously, it exerts pharmacological effects on osteoarthritic cartilage and chondrocytes. This product is for research use only.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level during short-term treatment.
- Decreases phosphorylation of p70S6K and S6, translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys.
- Appearance: white to off-white solid.
- Purity: 98.0%.