Life Science Buffers

Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.

Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.

Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.

The choice of buffer for a particular biological reaction or site depends on several factors:

Temperature
Desired or target pH
Buffer toxicity (to the system)
Buffer interactions with other system components

421 – 435 of 3,051 results

421

MP Biomedicals™ SM Buffer

SM Buffer is a sterile solution.

Pricing & Availability

422

Gibco™ PBS, pH 7.4

Gibco PBS, pH 7.4, is a balanced salt solution ideal for cell culture applications. It lacks calcium, magnesium, and phenol red, preventing cell adhesion and assay interference. Trusted for quality, Gibco PBS ensures reliable results in cell washing, transport, and reagent preparation.

Pricing & Availability
Specifications

Physical Form	Liquid
pH	7.3 to 7.5
Manufacturing Quality	cGMP-compliant under the ISO 13485 standard
Chemical Name or Material	Phosphate Buffered Saline (PBS)
Recommended Storage	15°C to 30°C
Concentration	1 X
For Use With (Application)	Mammalian Cell Culture
Osmolality	280 - 315 mOsm/kg
Sterility	Sterile-filtered

423

MOPSO Sodium Salt, MP Biomedicals™

CAS: 79803-73-9 Molecular Formula: C7H14NNaO5S Molecular Weight (g/mol): 247.24 InChI Key: WSFQLUVWDKCYSW-UHFFFAOYNA-M IUPAC Name: sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate SMILES: [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O

Pricing & Availability
Specifications

CAS	79803-73-9
Molecular Weight (g/mol)	247.24
SMILES	[Na+].OC(CN1CCOCC1)CS([O-])(=O)=O
IUPAC Name	sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate
InChI Key	WSFQLUVWDKCYSW-UHFFFAOYNA-M
Molecular Formula	C7H14NNaO5S

424

Tris, Cell Culture Reagent, ≥99.95%, MP Biomedicals™

Tris, Cell Culture Reagent, ≥99.95% is a biological buffer for various applications.

Pricing & Availability

425

PIPES, Ultrapure Bioreagent, J.T. Baker™

Pricing & Availability

426

MilliporeSigma™ BIS-Tris, ULTROL™ Grade, Calbiochem™,

CAS: 6976-37-0 Molecular Formula: C8H19NO5 Molecular Weight (g/mol): 209.242 InChI Key: OWMVSZAMULFTJU-UHFFFAOYSA-N Synonym: [bis(2-Hydroxyethyl)imino]-tris(hydroxymethyl)methane PubChem CID: 81462 ChEBI: CHEBI:41250 IUPAC Name: 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol SMILES: C(CO)N(CCO)C(CO)(CO)CO

Pricing & Availability
Specifications

PubChem CID	81462
CAS	6976-37-0
Molecular Weight (g/mol)	209.242
ChEBI	CHEBI:41250
SMILES	C(CO)N(CCO)C(CO)(CO)CO
Synonym	[bis(2-Hydroxyethyl)imino]-tris(hydroxymethyl)methane
IUPAC Name	2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol
InChI Key	OWMVSZAMULFTJU-UHFFFAOYSA-N
Molecular Formula	C8H19NO5

427

MilliporeSigma™ HEPES, Free Acid, ULTROL™ Grade, Calbiochem™,

CAS: 7365-45-9 Molecular Formula: C8H18N2O4S Molecular Weight (g/mol): 238.30 MDL Number: MFCD00006158 InChI Key: JKMHFZQWWAIEOD-UHFFFAOYSA-N Synonym: N-2-Hydroxyethylpiperazine-N'-2-ethanesulfonic Acid PubChem CID: 23831 ChEBI: CHEBI:42334 IUPAC Name: 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid SMILES: OCCN1CCN(CCS(O)(=O)=O)CC1

Pricing & Availability
Specifications

PubChem CID	23831
CAS	7365-45-9
Molecular Weight (g/mol)	238.30
ChEBI	CHEBI:42334
MDL Number	MFCD00006158
SMILES	OCCN1CCN(CCS(O)(=O)=O)CC1
Synonym	N-2-Hydroxyethylpiperazine-N'-2-ethanesulfonic Acid
IUPAC Name	2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid
InChI Key	JKMHFZQWWAIEOD-UHFFFAOYSA-N
Molecular Formula	C8H18N2O4S

428

MilliporeSigma™ Bicine, ULTROL™ Grade, Calbiochem™,

CAS: 150-25-4 Molecular Formula: C6H12NNaO4 Molecular Weight (g/mol): 185.16 MDL Number: MFCD00004295 InChI Key: MFBDBXAVPLFMNJ-UHFFFAOYSA-M Synonym: N,N-bis-(2-Hydroxyethyl)glycine PubChem CID: 8761 ChEBI: CHEBI:40957 IUPAC Name: sodium 2-[bis(2-hydroxyethyl)amino]acetate SMILES: [Na+].OCCN(CCO)CC([O-])=O

Pricing & Availability
Specifications

PubChem CID	8761
CAS	150-25-4
Molecular Weight (g/mol)	185.16
ChEBI	CHEBI:40957
MDL Number	MFCD00004295
SMILES	[Na+].OCCN(CCO)CC([O-])=O
Synonym	N,N-bis-(2-Hydroxyethyl)glycine
IUPAC Name	sodium 2-[bis(2-hydroxyethyl)amino]acetate
InChI Key	MFBDBXAVPLFMNJ-UHFFFAOYSA-M
Molecular Formula	C6H12NNaO4

429

Invitrogen™ xMAP Sheath Fluid Plus

xMAP Sheath Fluid Plus is the delivery medium that carries the sample to the optics component of Luminex xMAP technology-based instruments

Pricing & Availability

430

MilliporeSigma™ MOPS, Free Acid, Molecular Biology Grade, Calbiochem™,

CAS: 1132-61-2 Molecular Formula: C7H15NO4S Molecular Weight (g/mol): 209.26 MDL Number: MFCD00006183 InChI Key: DVLFYONBTKHTER-UHFFFAOYSA-N Synonym: 3-(N-Morpholino)propanesulfonic Acid PubChem CID: 70807 ChEBI: CHEBI:44115 IUPAC Name: 4-(3-sulfonatopropyl)morpholin-4-ium SMILES: [O-]S(=O)(=O)CCC[NH+]1CCOCC1

Pricing & Availability
Specifications

PubChem CID	70807
CAS	1132-61-2
Molecular Weight (g/mol)	209.26
ChEBI	CHEBI:44115
MDL Number	MFCD00006183
SMILES	[O-]S(=O)(=O)CCC[NH+]1CCOCC1
Synonym	3-(N-Morpholino)propanesulfonic Acid
IUPAC Name	4-(3-sulfonatopropyl)morpholin-4-ium
InChI Key	DVLFYONBTKHTER-UHFFFAOYSA-N
Molecular Formula	C7H15NO4S

431

MilliporeSigma™ MES, Sodium Salt, ULTROL™ Grade, Calbiochem™,

CAS: 71119-23-8 Molecular Formula: C6H12NNaO4S Molecular Weight (g/mol): 217.215 InChI Key: IRHWMYKYLWNHTL-UHFFFAOYSA-M Synonym: 2-(N-Morpholino)ethanesulfonic Acid, Na PubChem CID: 23673676 ChEBI: CHEBI:62955 IUPAC Name: sodium;2-morpholin-4-ylethanesulfonate SMILES: C1COCCN1CCS(=O)(=O)[O-].[Na+]

Pricing & Availability
Specifications

PubChem CID	23673676
CAS	71119-23-8
Molecular Weight (g/mol)	217.215
ChEBI	CHEBI:62955
SMILES	C1COCCN1CCS(=O)(=O)[O-].[Na+]
Synonym	2-(N-Morpholino)ethanesulfonic Acid, Na
IUPAC Name	sodium;2-morpholin-4-ylethanesulfonate
InChI Key	IRHWMYKYLWNHTL-UHFFFAOYSA-M
Molecular Formula	C6H12NNaO4S

432

MilliporeSigma™ MOPS, Free Acid, ULTROL™ Grade, Calbiochem™,

Pricing & Availability
Specifications

PubChem CID	70807
CAS	1132-61-2
Molecular Weight (g/mol)	209.26
ChEBI	CHEBI:44115
MDL Number	MFCD00006183
SMILES	[O-]S(=O)(=O)CCC[NH+]1CCOCC1
Synonym	3-(N-Morpholino)propanesulfonic Acid
IUPAC Name	4-(3-sulfonatopropyl)morpholin-4-ium
InChI Key	DVLFYONBTKHTER-UHFFFAOYSA-N
Molecular Formula	C7H15NO4S

433

POPSO, 0.2M buffer soln., pH 8.0, Thermo Scientific™

CAS: 108321-07-9 Molecular Formula: C10H20N2Na2O8S2 Molecular Weight (g/mol): 406.376 MDL Number: MFCD00070005 InChI Key: XMRCLLXGMGEVHS-UHFFFAOYSA-L PubChem CID: 53393457 IUPAC Name: disodium;2-hydroxy-3-[4-(2-hydroxy-3-sulfonatopropyl)piperazin-1-yl]propane-1-sulfonate SMILES: C1CN(CCN1CC(CS(=O)(=O)[O-])O)CC(CS(=O)(=O)[O-])O.[Na+].[Na+]

Pricing & Availability
Specifications

PubChem CID	53393457
CAS	108321-07-9
Molecular Weight (g/mol)	406.376
MDL Number	MFCD00070005
SMILES	C1CN(CCN1CC(CS(=O)(=O)[O-])O)CC(CS(=O)(=O)[O-])O.[Na+].[Na+]
IUPAC Name	disodium;2-hydroxy-3-[4-(2-hydroxy-3-sulfonatopropyl)piperazin-1-yl]propane-1-sulfonate
InChI Key	XMRCLLXGMGEVHS-UHFFFAOYSA-L
Molecular Formula	C10H20N2Na2O8S2

434

MOPS-EDTA-sodium acetate buffer (MESA), Thermo Scientific™

Pricing & Availability
Specifications

MDL Number	MFCD00131625
Physical Form	Liquid
Health Hazard 1	H335
Chemical Name or Material	MOPS-EDTA-sodium acetate buffer (MESA)
TSCA	Yes
Recommended Storage	Ambient temperatures

435

Thermo Scientific Chemicals Potassium phosphate, 0.5M buffer soln., pH 7.2

CAS: 7778-77-0 Molecular Formula: H2KO4P Molecular Weight (g/mol): 136.08 MDL Number: MFCD00011401 MFCD00147253 InChI Key: GNSKLFRGEWLPPA-UHFFFAOYSA-M IUPAC Name: potassium dihydrogen phosphate SMILES: [K+].OP(O)([O-])=O

Pricing & Availability
Specifications

CAS	7778-77-0
Molecular Weight (g/mol)	136.08
MDL Number	MFCD00011401 MFCD00147253
SMILES	[K+].OP(O)([O-])=O
IUPAC Name	potassium dihydrogen phosphate
InChI Key	GNSKLFRGEWLPPA-UHFFFAOYSA-M
Molecular Formula	H2KO4P

Life Science Buffers

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