Drug Standards
Medchemexpress LLC Deshydroxyethoxy-2,3-O-(dimethylmethylene) ticagrelor | 274693-49-1 | 10 MG
Ticagrelor impurity 22 is an analytical reference standard used as a drug impurity reference for analytical and research applications. It is characterized by CAS 274693-49-1 and molecular formula C24H28F2N6O3S, with a molecular weight of 518.58 g/mol. The manufacturer provides a datasheet and certificate of analysis with recommended storage and handling instructions.
- Intended for analytical and research use only.
- Provides a defined reference for impurity profiling and method validation.
- Characterized by CAS 274693-49-1 and molecular formula C24H28F2N6O3S.
- Supplied in small laboratory quantities for analytical workflows.
- Store per certificate of analysis; check CoA for exact conditions.
U.S. Pharmacopeia Gemcitabine hydrochloride, 122111-03-9, MFCD01735988, 200 mg
Empirical Formula (Hill Notation): C9H11F2N3O4 · HCl, Molecular Weight: 299.66, Synonym: 2′-Deoxy-2′,2′-difluorocytidine; dFdC, Gemzar (Lilly), LY-188011, dFdC, dFdCyd.
Medchemexpress LLC Lenalidomide-5-br | 1010100-26-1 | MFCD32263142 | 99.9% | 323.15 g/mol | C13H11BrN2O3 | 25 G
Lenalidomide-5-br is a brominated derivative of lenalidomide that acts as a cereblon (CRBN) ligand and is used to recruit CRBN in targeted protein degradation workflows such as PROTAC development. The compound is supplied as a solid with high stated purity and is available in multiple laboratory-scale package sizes.
- CRBN ligand suitable for PROTAC development and targeted protein degradation studies.
- Supplied as a solid with high stated purity for research use.
- Available in multiple package sizes for laboratory needs.
- Molecular formula C13H11BrN2O3 and molecular weight 323.15 g/mol.
- CAS number 1010100-26-1 for unambiguous identification.
Medchemexpress LLC Celecoxib (Standard) | 169590-42-5 | 99.97% | C17H14F3N3O2S | 50 MG
Celecoxib (Standard) is the analytical standard of Celecoxib, intended for research and analytical applications. Celecoxib itself is a selective non-steroidal anti-inflammatory drug (NSAID) and a selective COX-2 inhibitor with an IC50 of 40 nM. The compound is of analytical standard grade, serving as a reference standard for assays and commonly utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for Celecoxib
- Intended for research and analytical applications
- Used as a reference standard supplied assay
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Sigma Aldrich Fine Chemicals Biosciences Famotidine for system suitability European Pharmacopoeia (EP) Reference Standard | 76824-35-6 | MFCD00079297 |
Famotidine for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 337.45 | 76824-35-6 | MFCD00079297 |
Medchemexpress LLC Citalopram (hydrobromide) | 59729-32-7 | 99.9% | 100 MG
Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI), with blood-brain barrier permeability. It inhibits 5-HT uptake into synaptosomes and in rabbit blood platelets, exhibiting an antidepressant effect. It also demonstrates concentration-dependent cytotoxicity on the viability of various rat and human neuroblastoma cell lines and human primary Schwann cells.
- Selective serotonin reuptake inhibitor (SSRI)
- Blood-brain barrier permeability
- Inhibits 5-HT uptake
- Antidepressant effect
Medchemexpress LLC Tenofovir Disoproxil fumarate | 202138-50-9 | 99.5% | 635.51 | 50 MG
Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. It is for research use only.
- Used to treat HIV and chronic Hepatitis B
- Functions as a nucleotide reverse transcriptase inhibitor
- Shows cytotoxic effects on HK-2 cells with IC50 values of 9.21 and 2.77 μM at 48 and 72 hours
- Diminishes ATP levels and increases oxidative stress in HK-2 cells
- Induces apoptosis in HK-2 cells via mitochondrial damage
- Inhibits replication of R5-tropic HIV-1BaL and X4-tropic HIV-1IIIb in activated PBMCs
- Significantly reduces HIV transmission in BLT mice
- Induces dose-dependent decline in serum viremia in woodchucks chronically infected with WHV
- Demonstrated as safe and effective in the woodchuck model of chronic HBV infection
Medchemexpress LLC Iodixanol | 92339-11-2 | MFCD00867965 | 100.0% | 1 G
Iodixanol is an iodine-containing non-ionic radiocontrast agent used for research purposes. It is noted for exhibiting less kidney toxicity.
- Iodine-containing non-ionic radiocontrast agent
- Exhibits less kidney toxicity
- For research use only
Medchemexpress LLC Berberine hemisulfate | 316-41-6 | 384.40 | 5 G
Berberine hemisulfate is the hemisulfate form of Berberine. It is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective, and neuroprotective activity.
- Exhibits antimicrobial activity by inhibiting cell division protein FtsZ, or through DNA/RNA binding causing DNA/RNA damage.
- Exhibits anti-inflammatory activity by inhibiting TNF-α and the activation of its downstream pathway AP-1 and NF-kB.
- Exhibits neuroprotective efficacy by inhibiting reactive oxygen species (ROS) production and caspase activation, and activating the PI3K/Akt signaling pathway and heme oxygenase-1 (HO-1) expression.
- Attenuates metabolic diseases through regulations of lipid composition and inhibition of insulin resistance.
Medchemexpress LLC Curcumin-β-d-glucuronide | 227466-72-0 | MFCD28963761 | 98.0% | 544.50 | 1 ML
Curcumin-β-d-glucuronide is a major metabolite after oral intake of Curcumin, found in hepatic tissue and portal blood. It is used for research on colon cancer and has demonstrated anticancer properties in mouse tumor models and human metastatic colorectal cancer cell lines by promoting apoptosis. It also shows potential as a colon cancer prevention agent and possesses anti-inflammatory attributes by inhibiting prostaglandin E2 (PGE2) levels.
- Major metabolite of curcumin
- Exhibits anticancer properties
- Promotes apoptosis in cancer cells
- Potential colon cancer prevention agent
- Possesses anti-inflammatory attributes
- Inhibits prostaglandin E2 (PGE2) levels
Sigma Aldrich Fine Chemicals Biosciences Sodium ascorbate European Pharmacopoeia (EP) Reference Standard | 134-03-2 | MFCD00082340 |
Sodium ascorbate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 198.11 | 134-03-2 | MFCD00082340 |
TARGETMOL CHEMICALS INC RUXOLITINIB PHOSPHATE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ruxolitinib phosphate (INCB018424)(INCB018424 phosphate) is the first potent selective JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM >130-fold selectivity for JAK1/2 versus JAK3. purity: 99%
Medchemexpress LLC Bromfenac (sodium) | 91714-93-1 | 99.9% | 5MG
Bromfenac (sodium) | 91714-93-1 | 99.9% | 5MG