Drug Standards
Selleck Chemical LLC Itraconazole S2476-200mg
Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6 1 nM used as a triazole antifungal agent Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway Itraconazole suppresses the growth of glioblastoma through induction of autophagy
Selleck Chemical LLC Haloperidol 5mg 52-86-8
Haloperidol (Haldol) is an antipsychotic and butyrophenone. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Ranolazine Related Compound C United States Pharmacopeia (USP) Reference Standard | 5294-61-1 | 50MG
Ranolazine Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 247.34 | 5294-61-1 | 50MG
Sigma Aldrich Fine Chemicals Biosciences Misoprostol European Pharmacopoeia (EP) Reference Standard | 59122-46-2 | MFCD00274550 |
Misoprostol European Pharmacopoeia (EP) Reference Standard | Mol Wt: 382.53 | 59122-46-2 | MFCD00274550 |
Apexbio Technology LLC Fluconazole hydrate 155347-36-7 10mM (in 1mL DMSO)
Fluconazole hydrate (CAS 155347-36-7) is a small-molecule inhibitor targeting the fungal enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and arresting fungal growth Fluconazole hydrate exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies fluconazole hydrate demonstrates inhibitory activity with documented IC50 values typically ranging from 0 1 to 10 g/mL depending on fungal strain and experimental conditions Based on these pharmacological properties fluconazole hydrate holds research potential in antifungal pharmacology assays fungal infection model studies and evaluation of combinational antifungal therapies
Apexbio Technology LLC Dibucaine 85-79-0 500mg
Dibucaine (CAS 85-79-0) is an aminoamide local anesthetic known to inhibit rapid axonal transport of proteins In in vitro assays Dibucaine at 0 5 mM exhibited a level of transport blockade comparable to 1 mM tetracaine while 1 mM Dibucaine reduced radiolabeled protein accumulation at ligation sites by 92% and 0 5 mM by 72% These properties underline its utility in studies investigating the mechanisms underlying axonal transport and the effects of local anesthetics on neuronal function
Cayman Chemical 6-AmInocaproIc AcId 50g
An inhibitor of the plasmin activating enzymes streptokinase, fibrinokinase, and urokinase (IC50s = ~8 μM for all in an enzyme assay); selective for plasmin activating enzymes over trypsin (IC50 = >500 μM); inhibits in vitro plasmin activation and fibrinolysis in a dose-dependent manner; reduces ex vivo fibrinolysis in dog plasma following i.p. administration at doses ranging from 20-100 mg/kg
Apexbio Technology LLC Salinomycin 53003-10-4 10mg
Salinomycin is a polyether ionophore antibiotic derived from Streptomyces albus with demonstrated antitumor activities against various cancer cell types It is proposed to function by disrupting multiple signaling pathways including Wnt/ -catenin signaling and interference with ABC drug transport proteins In vitro research on human hepatocellular carcinoma (HCC) cell lines HepG2 SMMC-7721 and BEL-7402 indicates antiproliferative effects with IC50 values of 7 7 M 13 7 M and 10 4 M respectively after 24-hour treatment Studies show that salinomycin induces cell cycle arrest apoptosis via increased Bax/Bcl-2 ratio reduces -catenin expression and elevates intracellular calcium concentrations In vivo assays using orthotopic liver cancer models corroborate its antiproliferative and pro-apoptotic activities suggesting utility in oncology research
Cambridge Isotope Laboratories IN VIVO ILVA METHYL LABELING KIT, EA
IN VIVO ILVA METHYL LABELING KIT, EA
Medchemexpress LLC 3,5-bis(2-cyanoprop-2-yl)benzyl bromide | 120511-84-4 | MFCD07782114 | 5g
Anastrozole impurity 1 is an impurity of Anastrozole (HY-14274)
Medchemexpress LLC Tyloxapol | 25301-02-4 | 10 G
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, functioning as a surface active stabilizer. It is utilized to induce hyperlipidemia in animals, characterized by high levels of plasma triglycerides and LDL-cholesterol, and reduced HDL-cholesterol. It can increase plasma cholesterol levels by promoting hepatic cholesterol synthesis and disturbing lipolytic enzymes, blocking lipid uptake from circulation.
- Used to induce hyperlipidemia in animals
- Triggers detachment of HEK293 cells
- Induces nuclear fragmentation and apoptotic nuclei
- Increases risk of pulmonary hemorrhage and causes cytotoxicity
- Reduces AChE and MAO enzyme activities in rat plasma and brain
- Leads to reduction in plasma urea, creatinine, and bilirubin
- Appearance: liquid
- Color: colorless to light yellow
Apexbio Technology LLC Econazole nitrate 24169-02-6 5g
Econazole nitrate (24169-02-6) is a small-molecule inhibitor targeting the enzyme 14 -demethylase It is designed to disrupt ergosterol synthesis in fungal membrane sterol biosynthesis thereby decreasing membrane integrity altering permeability and attenuating fungal cellular growth Econazole nitrate exerts its biological activity primarily through inhibition of 14 -demethylase In vitro studies demonstrate antifungal activity with reported IC50 values against various fungal isolates typically ranging from approximately 0 05 to 1 g/mL depending on experimental parameters and organism specificity Based on these pharmacological properties econazole nitrate holds research potential in antifungal susceptibility testing exploration of drug resistance mechanisms in fungal strains characterization of dermatopathogenic microorganisms and drug target identification studies
Selleck Chemical LLC Lenalidomide S1029-1g
Lenalidomide is a TNF- secretion inhibitor with IC50 of 13 nM in PBMCs Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) and it causes selective ubiquitination and degradation of two lymphoid transcription factors IKZF1 and IKZF3 by the CRBN-CRL4 ubiquitin ligase Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis
Med Vet International Levofloxacin Tablets (levaquin) 750mg 20ct
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Levofloxacin Tablets (levaquin) 750mg 20ct
![eMolecules 58207-97-9 | Tributyl[(1E)-2-(trimethylsilyl)ethenyl]stannane | Synthonix - Stock389.286 | C17H38SiSn | 97.000 | CCCC[Sn](CCCC)(CCCC)\C=C\[Si](C)(C)C | 1g | 525923828](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696588.jpg-250.jpg)
eMolecules 58207-97-9 | Tributyl[(1E)-2-(trimethylsilyl)ethenyl]stannane | Synthonix - Stock389.286 | C17H38SiSn | 97.000 | CCCC[Sn](CCCC)(CCCC)\C=C\[Si](C)(C)C | 1g | 525923828
Tributyl[(1E)-2-(trimethylsilyl)ethenyl]stannane | Synthonix - Stock | 58207-97-9389.286 | C17H38SiSn | 97.000 | CCCC[Sn](CCCC)(CCCC)\C=C\[Si](C)(C)C | 1g | 525923828