Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Nateglinide European Pharmacopoeia (EP) Reference Standard | 105816-04-4 | MFCD00875706 |
Nateglinide European Pharmacopoeia (EP) Reference Standard | Mol Wt: 317.42 | 105816-04-4 | MFCD00875706 |
Medchemexpress LLC Tivantinib | 905854-02-6 | 99.6% | C23H19N3O2 | 100 MG
Tivantinib is a highly selective c-Met tyrosine kinase inhibitor, notable for its low molecular weight and as the first orally available selective inhibitor of c-Met. It selectively inhibits c-Met activity in cell-free and cell-based assays, leading to dose-dependent loss of proliferative capacity or caspase-dependent apoptosis in c-Met-expressing cancer cell lines.
- Highly selective c-Met tyrosine kinase inhibitor
- First orally available selective inhibitor of c-Met
- Inhibits c-Met activity in cell-free and cell-based assays
- Induces dose-dependent loss of proliferative capacity or caspase-dependent apoptosis in c-Met-expressing cancer cell lines
- Inhibits human recombinant c-Met with a Ki of approximately 355 nM
TARGETMOL CHEMICALS INC Naftifine hydrochloride 1G
Also available in 1 mL, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its effect is unknown, it appears to selectively inhibit the enzyme squalene 2, 3-epoxidase, thereby inhibiting the biosynthesis of sterol. This results in a decreased amount of sterols, especially ergosterol which is the primary fungal membrane sterol, and a corresponding accumulation of squalene in fungal cells. Naftifine hydrochloride (Naftifine HCl) can be fungicidal as well as fungistatic to yeasts depending on the concentration and the organisms involved. Purity 99.76%
Sigma Aldrich Fine Chemicals Biosciences Cefdinir Related Compound B United States Pharmacopeia (USP) Reference Standard | 79350-10-0 | 10MG
Cefdinir Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 366.42 | 79350-10-0 | 10MG
Cayman Chemical SynthetIc OuabaIn-d3 1mg
An internal standard for the quantification of ouabain by GC- or LC-MS
U.S. Pharmacopeia Lorazepam Related Compound D, 54643-79-7, MFCD06203519, 25 mg
Empirical Formula (Hill Notation): C15H8Cl2N2O2, Molecular Weight: 319.14, Synonym: 6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxylic acid.
Med Vet International Levofloxacin Tablets (levaquin) 750mg 20ct
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Levofloxacin Tablets (levaquin) 750mg 20ct
Medchemexpress LLC Isradipine | 75695-93-1 | MFCD00153820 | >98.0% | 371.39 | C19H21N3O5 | 10 MG
Isradipine is a dihydropyridine L-type calcium channel blocker used in research to modulate Cav1 family channels and study calcium-dependent cellular processes. Supplied as a research-grade solid in small pack sizes, it has molecular formula C19H21N3O5 and molecular weight 371.39 g/mol. Purity is specified per lot on the Certificate of Analysis; commercial grades are commonly ≥98% (HPLC).
- Dihydropyridine L-type calcium channel blocker for research use.
- Suitable for studies of calcium-dependent signaling and neuroprotection.
- Available in small pack sizes including 10 mg for screening and assay work.
- Molecular formula C19H21N3O5, molecular weight 371.39 g/mol.
- CAS number 75695-93-1 for unambiguous identification.
- Purity specified per lot; commercial grades typically ≥98% (HPLC).
- Supplied as a solid; follow the Certificate of Analysis for storage instructions.
Apexbio Technology LLC Boceprevir 394730-60-0 100mg
Boceprevir is an oral inhibitor targeting hepatitis C virus (HCV) NS3 protease an enzyme essential for processing viral polyproteins during HCV replication The compound binds directly and reversibly to the NS3 enzyme s active site forming a covalent adduct through its ketoamide functionality Cell-based replicon assays demonstrated that boceprevir inhibits HCV replication in cultured hepatocytes with an IC90 of approximately 350 nM In preclinical studies boceprevir exhibited favorable selectivity towards HCV NS3 relative to human neutrophil elastase Commonly boceprevir is used in research investigating HCV replication mechanisms and NS3 enzyme function as well as in antiviral combination assays involving interferon-based regimens
Apexbio Technology LLC Methylprednisolone(Synonyms: Medrol, Depo-Medrol, Solu-Medrol, Advantan, Urbason, Metipred, Medrate, Metilprednisolone), 10mM (in 1mL DMSO), CAS: 83-43-2.
Methylprednisolone (CAS 83-43-2) is a synthetic glucocorticoid receptor agonist that exerts anti-inflammatory effects by inhibiting pro-inflammatory cytokines notably TNF- and modulating NF- B signaling pathways In vitro studies demonstrate that methylprednisolone reduces TNF production and enhances IL-10 synthesis in mouse macrophages upon LPS stimulation suppresses chemokine secretion from human peripheral blood mononuclear cells and inhibits acantholysis in skin cultures Animal models indicate that intravenous methylprednisolone administration attenuates inflammation decreases macrophage infiltration and tissue damage post-spinal cord injury Clinically methylprednisolone is investigated for therapeutic use in acute spinal cord injury severe vasculitis and lupus nephritis
Medchemexpress LLC Diphenhydramine hydrochloride | 147-24-0 | 99.93%
Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist exhibiting anti-cholinergic effects. This compound is capable of crossing the ovine blood-brain barrier.
- Inhibits cisplatin-induced cell death in kidney proximal tubular cells.
- Inhibits cell viability in CCRF-CEM and Jurkat cells.
- Induces apoptosis in CCRF-CEM and Jurkat cells.
- Increases expression of Bad and Bax, and decreases BCL-2 level in PANC-1 cells.
- Decreases expression of various phosphorylated proteins (p-AKT, p-mTOR, p-FoxO1, p-MDM2, p-NF-ĸB p65, and p-GSK-3) in PANC-1 cells.
- Inhibits cisplatin-induced kidney toxicity in mice.
- Reduces mortality in rats with acute, severe dichlorvos exposure.
Sigma Aldrich Fine Chemicals Biosciences Atomoxetine for impurity A identification European Pharmacopoeia (EP) Reference Standard | 82248-59-7 | MFCD06410992 |
Atomoxetine for impurity A identification European Pharmacopoeia (EP) Reference Standard | Mol Wt: 291.82 | 82248-59-7 | MFCD06410992 |
Sigma Aldrich Fine Chemicals Biosciences Losartan impurity D European Pharmacopoeia (EP) Reference Standard | 83857-96-9 | MFCD01934396 |
Losartan impurity D European Pharmacopoeia (EP) Reference Standard | Mol Wt: 186.64 | 83857-96-9 | MFCD01934396 |
Sigma Aldrich Fine Chemicals Biosciences Letrozole United States Pharmacopeia (USP) Reference Standard | 112809-51-5 | MFCD00866241 | 200MG
Letrozole United States Pharmacopeia (USP) Reference Standard | Mol Wt: 285.3 | 112809-51-5 | MFCD00866241 | 200MG
Sigma Aldrich Fine Chemicals Biosciences Schisandrin United States Pharmacopeia (USP) Reference Standard | 7432-28-2 | MFCD00905761 | 15MG
Schisandrin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 432.51 | 7432-28-2 | MFCD00905761 | 15MG