Drug Standards
Cayman Chemical HarpagosIde 25mg
An iridoid glycoside with diverse biological activities; inhibits LPS-induced increases in COX-2 and NO levels, as well as TNF mRNA expression in HepG2 cells from 50-200 µM; reduces synovial inflammation, joint destruction, and bone erosion in a mouse model of collagen-induced arthritis at 10 mg/kg; decreases substantia nigra pars compacta neuronal cell death and increases time spent on the rod in a rotarod test in a mouse model of MPTP-induced Parkinson’s disease
Sigma Aldrich Fine Chemicals Biosciences Plastic additive 14 European Pharmacopoeia (EP) Reference Standard | 3806-34-6 | MFCD00071522 |
Plastic additive 14 European Pharmacopoeia (EP) Reference Standard | Mol Wt: 733.03 | 3806-34-6 | MFCD00071522 |
Medchemexpress LLC Tiamulin fumarate | 55297-96-6 | 99.3% | 1 ML
Tiamulin fumarate is a diterpenic antibiotic commonly used in pigs and poultry to control infectious diseases, including airsacculitis caused by Mycoplasma spp. This semisynthetic derivative of the diterpene antibiotic Pleuromutilin binds to rRNA, preventing protein production, and is highly effective against various Mycoplasma strains, Spirochaetes, and gram-positive bacteria.
- Highly active against Mycoplasma strains (M. gallisepticum, M. synoviae, M. meleagridis, and M. iowae).
- Effective against Spirochaetes (Brachyspira hyodysenteriae, Brachyspira innocens, B. pilosicoli, B. intermedia).
- Active against gram-positive bacteria such as staphylococci, streptococci, Clostridia, and Arcanobacterium spp.
- Mechanism of action involves binding to the peptidyl transferase slot on the ribosome, inhibiting protein synthesis.
- Effective in treating avian intestinal spirochaetosis.
- For research use only.
Medchemexpress LLC Neratinib (Standard) | 698387-09-6 | 99.3% | 557.04 | 25 MG
Neratinib (Standard) is the analytical standard of Neratinib, intended for research and analytical applications. Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively.
- Analytical standard for Neratinib
- Used for research and analytical applications
- Orally available
- Irreversible
- Highly selective HER2 and EGFR inhibitor
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
Apexbio Technology LLC Capecitabine(Synonyms: Xeloda, Ro 09-1978, N4-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine), 5g, CAS: 154361-50-9.
Capecitabine (CAS 154361-50-9) chemically defined as N4-pentyloxycarbonyl-5 -deoxy-5-fluorocytidine is an anticancer fluoropyrimidine prodrug that enzymatically converts into the cytotoxic agent 5-fluorouracil (5-FU) through sequential activation by enzymes predominantly expressed in tumors and liver tissues Mechanistically Capecitabine induces apoptosis via Fas-dependent pathways particularly in cells with elevated thymidine phosphorylase (TP) activity as observed in engineered LS174T colon cancer cell lines In mouse xenograft models of colon carcinoma and hepatocellular carcinoma Capecitabine administration reduced tumor growth metastasis and recurrence correlating to PD-ECGF expression These characteristics make Capecitabine relevant in preclinical oncology studies investigating chemotherapy selectivity and tumor-targeted drug delivery
Apexbio Technology LLC Minocycline HCl(Synonyms: Minocycline hydrochloride, Minocin, Dynacin, Solodyn, Minomycin, Akamin, Arestin, Minostad), 100mg, CAS: 13614-98-7.
Minocycline HCl (CAS 13614-98-7) is a semisynthetic tetracycline derivative known for its broad-spectrum antimicrobial properties and biological activity beyond antibacterial effects It acts primarily by inhibiting bacterial protein synthesis through reversible binding to the 30S ribosomal subunit thus preventing aminoacyl-tRNA from attaching to the ribosome-mRNA complex Independent of its antibiotic activity minocycline exhibits anti-inflammatory neuroprotective and antiapoptotic effects potentially mediated by suppression of cellular inflammatory pathways reduction of microglial activation and modulation of apoptotic signaling These properties make minocycline a compound of considerable interest in preclinical research for studying inflammation-related pathologies and neurodegenerative disorders
Apexbio Technology LLC Isradipine (Dynacirc)(Synonyms: Dynacirc, Prescal, Lomir, PN 200-110, Isrodipine, (+/-)-Isradipine, Isradipex), 50mg, CAS: 75695-93-1.
Isradipine (Dynacirc CAS 75695-93-1) is a small molecule antagonist belonging to the dihydropyridine class of calcium channel blockers It functions primarily by inhibiting L-type voltage-gated calcium channels thereby decreasing intracellular calcium influx into cardiac and vascular smooth muscle cells This inhibitory effect relaxes vascular smooth muscle tissue leading to vasodilation and subsequent reduction in systemic blood pressure In biomedical research isradipine is studied for its potential neuroprotective properties related to calcium-mediated excitotoxicity offering implications for conditions associated with neuronal calcium imbalance
Medchemexpress LLC Eupatilin | 22368-21-4 | 344.32 | 100 MG
Eupatilin is a lipophilic flavonoid isolated from *Artemisia argyi Lévl. et Van.*, functioning as a PPARα agonist and possessing anti-apoptotic, anti-oxidative, and anti-inflammatory properties.
- PPARα agonist
- Anti-apoptotic activity
- Anti-oxidative activity
- Anti-inflammatory activity
Medchemexpress LLC Berberine sulfate (Natural Yellow 18 sulfate) | 633-66-9 | 433.43 | 1 ML
Berberine sulfate (Natural Yellow 18 sulfate) | 633-66-9 | 433.43 | 1 ML
TARGETMOL CHEMICALS INC BOCEPREVIR 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Boceprevir (SCH 503034) is a novel potent highly selective orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay. purity: 99%
Medchemexpress LLC Salbutamol (Standard) | 18559-94-9 | 99.9% | 100 MG
Salbutamol (Standard) is the analytical standard of Salbutamol, intended for research and analytical applications. Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. It promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway and is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD).
- Analytical standard, suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Appearance: Solid, white to off-white.
- Shipping: Room temperature in continental US; may vary elsewhere.
Medchemexpress LLC Dacomitinib impurity 16 | 2803456-91-7 | 25mg
Dacomitinib impurity 16 is an impurity of Dacomitinib (HY-13272)
Medchemexpress LLC Berberine (sulfate) | 633-66-9 | 433.43 | 50 MG
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, functioning as an antibiotic. It induces reactive oxygen species (ROS) generation, inhibits DNA topoisomerase, and possesses antineoplastic properties. The sulfate form of berberine is noted to improve its bioavailability.
- An alkaloid isolated from the Chinese herbal medicine Huanglian.
- Functions as an antibiotic.
- Induces reactive oxygen species (ROS) generation.
- Exhibits antineoplastic properties.
- Inhibits DNA topoisomerase.
- Sulfate form improves bioavailability.
Medchemexpress LLC Methyl gallate | 99-24-1 | 184.15 | 1 ML
Methyl gallate is a plant phenolic compound that exhibits antioxidant, anticancer, and anti-inflammatory activities. It also demonstrates bacterial inhibition, anti-HIV-1, and HIV-1 enzyme inhibitory activities.
- Plant phenolic with antioxidant activity.
- Possesses anticancer activities.
- Demonstrates anti-inflammatory activities.
- Shows activity in inhibiting bacteria.
- Found to have anti-HIV-1 and HIV-1 enzyme inhibitory activities.
- High purity.
- Intended for research use only.
Medchemexpress LLC Racemic voriconazole | 188416-29-7 | MFCD09263753 | 99.1% | 349.31 g/mol | C16H14F3N5O | 50 MG
(±)-Voriconazole is the racemic form of voriconazole, a triazole antifungal agent supplied as a white to off-white solid for laboratory research. It has molecular formula C16H14F3N5O, a molecular weight of 349.31 g/mol, and CAS number 188416-29-7. The material is provided in small milligram packaging for analytical and experimental use.
- High purity (99.06%) for reliable experimental results.
- White to off-white solid, easy to weigh and handle.
- Well-characterized chemical identifiers for accurate substance identification.
- Suitable for antifungal mechanism and biochemical studies.
- Provided in small, controlled quantities for research workflows.