Ion Chromatography Standards
THERMO SCI 3P AIG PARTS & ACCESSORIES AMMONIUM AS NH4 STD 984728
NC2590194 AMMONIUM AS NH4 STD 984728
Apexbio Technology LLC Etravirine (TMC125) 269055-15-4 1g
Etravirine (TMC125) (CAS 269055-15-4) is a small-molecule inhibitor targeting HIV-1 reverse transcriptase It is designed to block the activity of this enzyme thereby preventing HIV-1 viral replication Etravirine exerts its biological activity primarily through direct binding to HIV-1 reverse transcriptase as a non-nucleoside reverse transcriptase inhibitor (NNRTI) inducing conformational changes that reduce the enzyme s catalytic efficiency In cell-based assays Etravirine demonstrates potent inhibition of HIV-1 replication with reported IC50 values typically in the low nanomolar to sub-nanomolar range Based on these pharmacological properties Etravirine holds research potential in antiviral activity profiling resistance mutation analysis and mechanistic studies of reverse transcriptase function and HIV replication pathways
Waters Corp Waters Chlorate Ion Calibration Standard, 1000 mg/L, 125 mL, H2O
Waters Chlorate Ion Calibration Standard, 1000 mg/L, 125 mL, H2O
Apexbio Technology LLC Enoxolone 471-53-4 1g
Enoxolone (CAS 471-53-4) also known as glycyrrhetinic acid is a principal component of licorice with reported antiviral and antifungal activities It modulates corticosteroid signaling by inhibiting 11 -hydroxysteroid dehydrogenase (11 -HSD) isoenzymes in hepatic and renal tissues In rats the IC50 values for 18 -enoxolone-mediated inhibition of 11 -HSD activity are 0 09 M in liver and 0 36 M in kidney homogenates Enoxolone also suppresses 11 -HSD activity in human JEG-3 choriocarcinoma cells This compound is used in biomedical research to study glucocorticoid metabolism mineralocorticoid receptor specificity and enzyme regulation in steroidogenesis