Ion Chromatography Standards
Apexbio Technology LLC Nikethamide 59-26-7 1g
Nikethamide is a small-molecule respiratory stimulant designed to modulate the respiratory center in the medulla oblongata thereby regulating central respiratory sensitivity Nikethamide exerts its biological activity primarily through modulation of neural pathways within the central nervous system potentially involving nicotinic receptors and neurotransmitter signaling cascades Based on these pharmacological properties Nikethamide holds research potential in investigating respiratory dysfunction respiratory failure and the signaling mechanisms governing respiratory neural control
Apexbio Technology LLC Chondroitin sulfate 9007-28-7 1g
Chondroitin sulfate (9007-28-7) is a glycosaminoglycan designed to modulate inflammatory and apoptotic processes thereby regulating extracellular matrix homeostasis Chondroitin sulfate exerts its biological activity primarily by inhibiting inflammatory mediators and reducing cell apoptosis through interactions with various biological molecules Based on these pharmacological properties chondroitin sulfate holds research potential in investigating cartilage degradation inflammatory response mechanisms and therapeutic targets related to joint degeneration and tissue remodeling
Apexbio Technology LLC MCPA 94-74-6 1g
MCPA (CAS nan) is a small-molecule herbicide that modulates plant growth-regulating enzymes thereby disrupting physiological processes necessary for weed proliferation MCPA exerts its biological activity primarily through targeted enzymatic regulation involved in plant growth Experimental studies have demonstrated herbicidal activity of MCPA against various broadleaf species such as poppy thistle and reed plants Based on these pharmacological properties MCPA holds research potential in plant physiological investigations crop management research and the exploration of herbicide mechanisms at biochemical and molecular levels
Apexbio Technology LLC Fluocinonide 356-12-7 1g
Fluocinonide (CAS 356-12-7) is a synthetic glucocorticoid steroid targeting intracellular glucocorticoid receptors (GR) It is designed to modulate gene transcriptional activity thereby regulating the production and release of inflammatory cytokines and mediators in the inflammatory response pathway Fluocinonide exerts its biological activity primarily through binding to glucocorticoid receptors and forming receptor-ligand complexes which influence cellular and molecular inflammatory signaling cascades Based on these pharmacological properties fluocinonide holds research potential in studying pathophysiological mechanisms of inflammatory skin conditions evaluating topical corticosteroid metabolism and absorption and facilitating investigations focused on dermatological inflammatory responses
Apexbio Technology LLC EDTA 60-00-4 1g
EDTA (60-00-4) is a chelating agent targeting polyvalent metal ions such as calcium magnesium and iron It is designed to sequester metal ion cofactors thereby inhibiting metal-dependent enzymatic reactions and stabilizing proteins EDTA exerts its biological activity primarily through the formation of stable coordination complexes with metal ions preventing their participation in biochemical processes In biochemical and cell culture studies EDTA demonstrates inhibition of metal-dependent enzymes and preservation of reagent stability Based on these pharmacological properties EDTA holds research potential in protein purification nucleic acid isolation enzyme assays chromatography coronary artery disease and neurological disease studies
Apexbio Technology LLC Enoxolone 471-53-4 1g
Enoxolone (CAS 471-53-4) also known as glycyrrhetinic acid is a principal component of licorice with reported antiviral and antifungal activities It modulates corticosteroid signaling by inhibiting 11 -hydroxysteroid dehydrogenase (11 -HSD) isoenzymes in hepatic and renal tissues In rats the IC50 values for 18 -enoxolone-mediated inhibition of 11 -HSD activity are 0 09 M in liver and 0 36 M in kidney homogenates Enoxolone also suppresses 11 -HSD activity in human JEG-3 choriocarcinoma cells This compound is used in biomedical research to study glucocorticoid metabolism mineralocorticoid receptor specificity and enzyme regulation in steroidogenesis
Apexbio Technology LLC Perindopril 82834-16-0 1g
Perindopril (CAS 82834-16-0) is an inhibitor of angiotensin I-converting enzyme (ACE) widely used in biomedical research By blocking ACE activity Perindopril suppresses the formation of angiotensin II a peptide involved in vasoconstriction and angiogenesis In cancer studies Perindopril has demonstrated the ability to inhibit tumor growth and angiogenesis in head and neck squamous cell carcinoma models While it does not significantly affect cell proliferation in vitro it reduces VEGF mRNA expression and promoter activity at concentrations as low as 1 M In vivo Perindopril has been shown to suppress tumor growth and lower blood pressure without altering heart rate supporting its application in oncology and cardiovascular research
Apexbio Technology LLC Pasiniazid 2066-89-9 1g
Pasiniazid (CAS 2066-89-9) is a small-molecule inhibitor targeting enzymes essential for mycolic acid biosynthesis in mycobacteria It is designed to disrupt cell wall synthesis thereby inhibiting the growth of Mycobacterium tuberculosis and Mycobacterium leprae Pasiniazid exerts its biological activity primarily through inhibition of mycolic acid biosynthesis In in vitro antimicrobial assays and animal infection models Pasiniazid demonstrates inhibitory activity with reported IC50 values against mycobacterial targets typically within micromolar concentrations Based on these pharmacological properties Pasiniazid holds research potential in the investigation of tuberculosis and leprosy pathogenesis including studies on drug-response relationships resistance mechanisms and pharmacokinetics
Apexbio Technology LLC Rhodamine B 81-88-9 1g
Rhodamine B (81-88-9) is a synthetic fluorescent dye Its molecular structure enables excitation at specific wavelengths and emission of detectable fluorescence signals Rhodamine B is widely applied as a labeling agent in microscopy-based analyses facilitating visualization for intracellular labeling and tracking Researchers use Rhodamine B to stain cellular structures assess membrane permeability and monitor interactions of biomolecules such as proteins and nucleic acids Fluorescence intensity changes also support assays investigating enzyme activity apoptotic processes and intracellular uptake Based on these properties Rhodamine B holds research potential in cellular imaging biomolecular tracking and pharmaceutical distribution studies
Thermo Scientific Dionex™ Retention Time Standards for Ion Chromatography
Standard Components: Lithium 2 mg/L, Sodium 9 mg/L, Ammonium 3 mg/L, Potassium 21 mg/L, Magnesium 9 mg/L, Calcium 17 mg/L | For use with Routine Cation Determinations
Med Vet International Clonidine Hcl, .2mg, 100 Tablets
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clonidine hydrochloride
Apexbio Technology LLC Nizatidine 76963-41-2 1g
Nizatidine (CAS 76963-41-2) is a small molecule inhibitor primarily characterized as a potent histamine H2 receptor antagonist exhibiting an IC50 of 0 9 nM for this target In addition to its H2 receptor antagonism nizatidine also demonstrates inhibition of acetylcholinesterase (AChE) activity with an IC50 of 6 7 M These dual inhibitory properties make nizatidine a useful tool for investigating pathways involving gastric acid secretion and cholinergic neurotransmission in biomedical research settings