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Filtered Search Results
eMolecules AstaTech / 3-METHYLSULFONYLBENZOIC ACID / 1g / 233625254 / 34446 / 95.000 / 5345-27-7 / MFCD00216488 / 200.210 / C8H8O4S
AstaTech / 3-METHYLSULFONYLBENZOIC ACID / 1g / 233625254 / 34446 / 95.000 / 5345-27-7 / MFCD00216488 / 200.210 / C8H8O4S
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eMolecules Ambeed / Boc-Dap(Fmoc)-OH / 250mg / 525050267 / A141078 / / 122235-70-5 / MFCD00235897 / 426.469 / C23H26N2O6
Ambeed / Boc-Dap(Fmoc)-OH / 250mg / 525050267 / A141078 / / 122235-70-5 / MFCD00235897 / 426.469 / C23H26N2O6
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eMolecules Ambeed / 2-Chloro-6-methylisonicotinic acid / 250mg / 524998239 / A108650 / / 25462-85-5 / MFCD00052830 / 171.580 / C7H6ClNO2
Ambeed / 2-Chloro-6-methylisonicotinic acid / 250mg / 524998239 / A108650 / / 25462-85-5 / MFCD00052830 / 171.580 / C7H6ClNO2
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eMolecules Ambeed / 4-Hydroxybenzaldehyde / 25g / 552573906 / A138562 / / 123-08-0 / MFCD00006939 / 122.123 / C7H6O2
Ambeed / 4-Hydroxybenzaldehyde / 25g / 552573906 / A138562 / / 123-08-0 / MFCD00006939 / 122.123 / C7H6O2
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eMolecules Synthonix / 2-[(tert-butyldiphenylsilyl)oxy]ethanol / 250mg / 786491816 / AC80300 / / 138499-16-8 / MFCD28404092 / 300.473 / C18H24O2Si
Synthonix / 2-[(tert-butyldiphenylsilyl)oxy]ethanol / 250mg / 786491816 / AC80300 / / 138499-16-8 / MFCD28404092 / 300.473 / C18H24O2Si
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Sigma Aldrich Fine Chemicals Biosciences Dibenzo[a,e]fluoranthene BCR(R), certified reference material | 5385-75-1 | MFCD00215892 | 20MG
Dibenzo[a,e]fluoranthene BCR(R), certified reference material | Mol Wt: 302.37 | 5385-75-1 | MFCD00215892 | 20MG
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Medchemexpress LLC Metaproterenol (hemisulfate) | 5874-97-5 | 99.4% | 100 MG
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Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. It also exhibits anti-inflammatory activity.
- Functions as a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM.
- Possesses anti-inflammatory activity.
- Enhances β-arrestin2 and its interaction with IκBα in high glucose-induced THP-1 cells and bone marrow macrophages.
- Downregulates NF-κB in high glucose-induced THP-1 cells and bone marrow macrophages.
- Attenuates monocyte activation and pro-inflammatory and pro-fibrotic responses in the kidneys and heart of Zucker diabetic fatty rats, potentially offering protective effects against diabetic renal and cardiovascular complications.
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Medchemexpress LLC 1-(2-Chlorophenyl)-2-((2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)amino)ethan-1-ol hydrochloride | 1325559-14-5 | 99.0% | 1 MG
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Tulobuterol-d9 (hydrochloride) is the deuterium labeled Tulobuterol, a long-acting β2-adrenoceptor agonist. It is known to reduce the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. This compound also functions as a sympathomimetic agent when used as a transdermal patch, enhancing normal diaphragm muscle strength. It is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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eMolecules Ambeed / 35-Dimethylisoxazole-4-carbonyl chloride / 1g / 625594467 / A718537 / / 31301-45-8 / MFCD00052555 / 159.570 / C6H6ClNO2
Ambeed / 35-Dimethylisoxazole-4-carbonyl chloride / 1g / 625594467 / A718537 / / 31301-45-8 / MFCD00052555 / 159.570 / C6H6ClNO2
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eMolecules Ambeed / 34-Dimethylbenzoic acid / 250mg / 490540611 / A235591 / / 619-04-5 / MFCD00002524 / 150.177 / C9H10O2
Ambeed / 34-Dimethylbenzoic acid / 250mg / 490540611 / A235591 / / 619-04-5 / MFCD00002524 / 150.177 / C9H10O2
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Medchemexpress LLC UNC10217938A | 1347749-97-6 | 99.75% | 456.54 | 50 MG
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UNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. It enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes, and also enhances the effects of antisense and siRNA oligonucleotides.
- 3-deazapteridine analog with strong oligonucleotide enhancing effects.
- Enhances oligonucleotide effects by modulating intracellular trafficking and release from endosomes.
- Enhances the effects of antisense and siRNA oligonucleotides.
- Strongly enhances luciferase induction in HelaLuc705 cells.
- Can substantially enhance effects of receptor targeted oligonucleotide conjugates.
- Can enhance effects of uncharged morpholino oligonucleotides as well as negatively charged oligonucleotides.
- Causes partial release of oligonucleotide from late endosomes to the cytosol followed by nuclear accumulation.
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Medchemexpress LLC TL-895 | 1415823-49-2 | 99.9% | 447.50 | 50 MG
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TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor. It shows activity against recombinant BTK and effectively inhibits the production of inflammatory factors. This compound is used in studies of chronic lymphocytic leukemia (CLL), myelofibrosis (MF), and B-cell malignancies.
- Potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor
- Inhibits recombinant BTK (average IC50: 1.5 nM)
- Inhibits BLK, BMX, and TXK kinases
- Inhibits BTK auto-phosphorylation at the Y223 site (IC50: 1-10 nM)
- Effectively inhibits the production of inflammatory factors including IL-8, IL-1β, MCP-1, and TNF-α
- Reduces chemotactic migration of myelofibrosis cells towards SDF-1
- Used for studies of chronic lymphocytic leukemia, myelofibrosis, and B-cell malignancies
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Medchemexpress LLC Carubicin hydrochloride | 52794-97-5 | 98.3% | 50 MG
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Carubicin hydrochloride is a microbially-derived compound with potential for research related to cancer diseases.
- Inhibits VHL-defective CCRCC cell proliferation.
- Induces apoptosis independent of p53 or HIF2.
- Derived from microorganisms (bacterium Actinomadura carminata).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / 3-(Pyridin-4-yl)benzoic acid / 250mg / 570995642 / A239991 / / 4385-78-8 / MFCD05864808 / 199.209 / C12H9NO2
Ambeed / 3-(Pyridin-4-yl)benzoic acid / 250mg / 570995642 / A239991 / / 4385-78-8 / MFCD05864808 / 199.209 / C12H9NO2
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / 4-Methylpicolinic acid / 250mg / 525073840 / A159299 / / 4021-08-3 / MFCD03731175 / 137.138 / C7H7NO2
Ambeed / 4-Methylpicolinic acid / 250mg / 525073840 / A159299 / / 4021-08-3 / MFCD03731175 / 137.138 / C7H7NO2
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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